GEO DataSets

(Submitter supplied) The uncovering of genes involved in susceptibility to the sporadic cancer types is a great challenge. It is well established that the way in which an individual deals with DNA damage is related to the chance to develop cancer. Mutagen sensitivity is a phenotype that reflects an individual’s susceptibility to the major sporadic cancer types, including colon, lung and head and neck cancer. A standard test for mutagen sensitivity is measuring the number of chromatid breaks in lymphocytes after exposure to bleomycin. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS1714

Platform:

GPL2902

28 Samples

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Analysis of mutagen-sensitive lymphoblastoid cell lines after exposure to bleomycin. Mutagen-sensitive cells exhibit a high number of bleomycin-induced chromatid breaks. Mutagen sensitivity (MS) reflects an individual's susceptibility to sporadic cancers. Results identify genes involved in MS.

Organism:

Homo sapiens

Type:

Expression profiling by array, log2 ratio, 2 agent, 2 cell line sets

Platform:

GPL2902

Series:

GSE3598

28 Samples

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(Submitter supplied) - oligonucleotide sequences are available via www.ensemble.org after agreeing to Compugen's conditions - oligonucleotides were mapped by Ensembl to the NCBI35 version of the human genome Protocol: The Human Release 1.0 oligonucleotide library, containing 18861 60-mer oligonucleotides representing 17260 unique genes as designed by Compugen (San Jose, CA, USA) was obtained from Sigma-Genosys (Zwijndrecht, The Netherlands). more...

Organism:

Homo sapiens

1 DataSet

2 Series

45 Samples

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