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Items: 4

1.

Discovery of genes regulated by the metastasis suppressor gene, RhoGDI2

(Submitter supplied) A number of studies find that metastasis suppressor proteins, including RhoGDI2, may function in part though controlling expression of genes regulating metastasis (reviewed in Smith and Theodorescu, Nature Reviews Cancer, 2009, PMID: 19242414). To uncover systematically gene expression patterns dependent on RhoGDI2 expression, we profiled gene expression in stably transfected control (GFP empty vector) UM-UC-3 bladder carcinoma cells (which have lost endogenous expression of RhoGDI2, as occurs commonly in the progression of bladder cancer PMID: 15173088), as well as stably transfected GFP-tagged RhoGDI2 expressing UM-UC-3 cells. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4455
Platform:
GPL570
4 Samples
Download data: CEL
Series
Accession:
GSE35014
ID:
200035014
2.
Full record GDS4455

RhoGTP dissociation inhibitor 2 effect on UM-UC-3 bladder cancer cells

Analysis of UM-UC-3 bladder carcinoma cells (low RhoGDI2-expressing and highly metastatic) stably transfected with GFP-RhoGDI2. RhoGDI2 is a metastasis suppressor protein. Results provide insight into the molecular basis of RhoGD12-mediated blockage of prometastatic inflammatory host response.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 genotype/variation sets
Platform:
GPL570
Series:
GSE35014
4 Samples
Download data: CEL
3.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...
Organism:
Homo sapiens
602 DataSets
5674 Series
61 Related Platforms
175720 Samples
Download data
Platform
Accession:
GPL570
ID:
100000570
4.

GFP Replicate B

Organism:
Homo sapiens
Source name:
UM-UC-3 bladder cancer cells, stably transfected with GFP (control), biological replicate B
Platform:
GPL570
Series:
GSE35014
Dataset:
GDS4455
Download data: CEL
Sample
Accession:
GSM860662
ID:
300860662
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