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Items: 3

1.

Transcriptome-scale RNA-targeting CRISPR screens reveal essential lncRNAs in human cells

(Submitter supplied) Mammalian genomes host a diverse array of RNA that includes protein-coding and noncoding transcripts. However, the functional roles of most long noncoding RNAs (lncRNAs) remain elusive. Using massively parallel RNA-targeting CRISPR Cas13 screens, we probed how loss of ~6,200 lncRNAs impacts cell fitness across five human cell lines and identified 778 lncRNAs with either context-specific or broad essentiality. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL18573 GPL24676
12 Samples
Download data: TXT
Series
Accession:
GSE281460
ID:
200281460
2.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
3.

RfxCas13d expressing K562 cells, pooled lncRNA library, before, 7 days after, or 14 days after dox induction, rep2

Organism:
Homo sapiens
Source name:
bone marrow
Platform:
GPL18573
Series:
GSE281460
Download data
Sample
Accession:
GSM8621116
ID:
308621116
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