GSM863372[Accession] - GEO DataSets

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Items: 4

Select item 2000355091.

Lack of hepatic response of microRNA in mice following DB[a,h]A exposure

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Non-coding RNA profiling by array; Expression profiling by array

Platforms:: GPL13912 GPL14972
38 Samples

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Series

Accession:: GSE35509

ID:: 200035509

Select item 2000351952.

Lack of hepatic response of microRNA in mice following DB[a,h]A exposure (Agilent miRNA)

(Submitter supplied) Dibenzo[a,h]anthracene DB[a,h]A is a polycyclic aromatic hydrocarbon potent carcinogen. Few studies have investigated the role of DB[a,h]A on mRNA and miRNA expression. In this study a 10-week old male MutaTM Mouse were exposed to 6.25, 12.5, and 25 mg/kg/day DB[a,h]A by oral gavage for 28 consecutive days. DNA adducts were detected in the livers at each DB[a,h]A dose tested, and a dose-dependent increase in lacZ mutants was observed in the same samples. more...