GSM877055[Accession] - GEO DataSets

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Items: 3

Select item 2000358881.

Mapping Clinical and Expression QTL in a Sex-Dependent Effect of Host Susceptibility to Influenza H3N2/HK/1/68-MA20

(Submitter supplied) Seasonal influenza outbreaks and recurrent influenza pandemics present major challenges to public health. By studying immunological responses to influenza in different host species, it may be possible to discover common mechanisms of susceptibility in response to various influenza strains. This could lead to novel therapeutic targets with wide clinical application. Using a mouse-adapted strain of influenza (A/HK/1/68-MA20 [H3N2]), we produced a mouse model of severe influenza (p-flu) that reproduces the hallmark high viral load and overexpression of cytokines associated with susceptibility to p-flu in humans. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL81
54 Samples

Download data: CEL

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Accession:: GSE35888

ID:: 200035888

Select item 1000000812.

[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 24, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The MG-U74 set includes 3 arrays with a total of 36899 entries and was indexed 29-Jan-2002. more...