GEO DataSets

(Submitter supplied) Objective. Colchicine is an alkaloid that is used to alleviate acute gout and to prevent acute attacks of familial Mediterranean fever (FMF). However, it is not beneficial when given during the occurrence of an acute episode of FMF. It is believed that colchicine exerts its anti-inflammatory effect through direct interaction with microtubules. We aim to study the molecular basis of colchicine action by analysing the effect of this drug on global gene expression of HUVEC (human umbilical vein endothelial cell line) cells. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS1753

Platform:

GPL3386

16 Samples

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Analysis of umbilical vein endothelial cell line HUVEC at various time points up to 24 hours following treatment with 100 ng/ml or 1 ug/ml of colchicine. Colchicine is an alkaloid used to alleviate rheumatic complaints like gout and to prevent acute attacks of familial Mediterranean fever.

Organism:

Homo sapiens

Type:

Expression profiling by array, log2 ratio, 3 dose, 5 time sets

Platform:

GPL3386

Series:

GSE4090

16 Samples

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(Submitter supplied) Material is transferred from microtiter plate wells to the slide surface by an automated print head

Organism:

Homo sapiens

1 DataSet

2 Series

19 Samples

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