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Items: 4

1.

Acquired resistance to lapatinib

(Submitter supplied) These studies are aimed at understanding gene expression chnages in a Her2 positive breast cancer cell line that has developed acquired resistance to lapatinib. Samples include SKBR3 parental and resistant (SKBR3-R) under basal conditions and in response to 0.1 and 1uM lapatinib treatment after 24 hours.
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4979
Platform:
GPL6947
18 Samples
Download data: TXT
Series
Accession:
GSE38376
ID:
200038376
2.
Full record GDS4979

Lapatinib effect on lapatinib-resistant ErbB2-positive cell line: dose response

Analysis of lapatinib-resistant ErbB2-positive cells treated with 0.1 or 1 uM lapatinib. Lapatinib is an EGFR/ErbB2 inhibitor used to treat ErbB2‐positive advanced or metastatic breast cancer. Results provide insight into the mechanisms underlying the development of resistance to lapatinib.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 cell type, 3 dose sets
Platform:
GPL6947
Series:
GSE38376
18 Samples
Download data
3.

Illumina HumanHT-12 V3.0 expression beadchip

(Submitter supplied) The HumanHT-12 V3.0 Expression BeadChip features up-to-date content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36.2, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. These should be submitted as part of a GEOarchive. more...
Organism:
Homo sapiens
13 DataSets
542 Series
1 Related Platform
26115 Samples
Download data: BGX
Platform
Accession:
GPL6947
ID:
100006947
4.

SKBR3_Control_1

Organism:
Homo sapiens
Source name:
human breast cancer cell line
Platform:
GPL6947
Series:
GSE38376
Dataset:
GDS4979
Download data
Sample
Accession:
GSM940873
ID:
300940873
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