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Items: 4

1.

Hypoxic changes in gene expression: effect of vhl and p53 genotype

(Submitter supplied) Microarrray experiments were performed in order to identify genes whose expression is altered under hypoxic conditions and to determine whether these changes are dependant on the p53 and HIF tanscription factors. In order to determine HIF dependance, isogenic RCC4 cell lines were used that were either wildtype of null for vhl, the gene responsible for degrading HIF under normoxic conditions. In order to determine p53 dependance, isogenic HCT116 and H1299 cell lines that were wildtype or null for p53 were used. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS1772
Platform:
GPL3423
30 Samples
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Series
Accession:
GSE4186
ID:
200004186
2.
Full record GDS1772

Hypoxia effect on vhl and p53 null mutants

Analysis of cell lines lacking VHL or p53 following exposure to hypoxia. VHL is the gene responsible for degrading transcription factor HIF-1. p53 null mutants examined to identify genes whose expression under hypoxia depends on p53. Results identify genes regulated by HIF-1.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 cell line, 4 genotype/variation, 4 stress, 8 time sets
Platform:
GPL3423
Series:
GSE4186
30 Samples
Download data
DataSet
Accession:
GDS1772
ID:
1772
3.

Stanford Denko EOS Human 35K Genechip v1.1

(Submitter supplied) see manufacturer's website
Organism:
Homo sapiens
1 DataSet
1 Series
30 Samples
Download data
Platform
Accession:
GPL3423
ID:
100003423
4.

RCC4vhl+ hypoxia 6hrs rep1

Organism:
Homo sapiens
Source name:
RCC4 vhl wildtype cells exposed to hypoxia 6hrs
Platform:
GPL3423
Series:
GSE4186
Dataset:
GDS1772
Download data
Sample
Accession:
GSM95561
ID:
300095561
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Supplemental Content

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