GEO DataSets

(Submitter supplied) In more than 70% of families with a strong history of breast and ovarian cancers, pathogenic mutation in BRCA1 or BRCA2 cannot be identified, even though hereditary factors are expected to be involved. It has been proposed that tumors with similar molecular phenotypes also share similar pathophysiological mechanisms. Grouping into molecularly homogeneous subsets may therefore be of potential value for further genetic analysis in order to identify new high penetrance breast cancer genes. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL15931

253 Samples

Download data: TXT

(Submitter supplied) Microarray is a powerful technique that has been used extensively for genome-wide gene expression analysis. Several different microarray technologies are available, but lack of standardization makes it challenging to compare and integrate data from different platforms. Furthermore, batch related biases within datasets are common, but are often not tackled prior to the data analysis, potentially affecting the end results. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platforms:

GPL15932 GPL15931

486 Samples

Download data: GPR, TXT

(Submitter supplied) Pathogenic germline mutations in BRCA1 or BRCA2 are detected in less than one third of families with a strong history of breast cancer. It is therefore expected that mutations still remain undetected by currently used screening methods. In addition, a growing number of BRCA1/2 sequence variants of unclear pathogen significance are found in the families, constituting an increasing clinical challenge. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platforms:

GPL15932 GPL15931

275 Samples

Download data: GPR, TXT

(Submitter supplied) Custom SurePrint G3 Human GE 8x60K Microarray Arrays of this design have barcodes that begin with 16029949 or 2529949. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. Rows and columns are numbered as scanned by an Axon Scanner (barcode on the bottom, DNA on the front surface). more...

Organism:

Homo sapiens

4 Series

417 Samples

Download data: TXT