GSM985442[Accession] - GEO DataSets - NCBI

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Items: 3

Select item 2000401171.

Analyses of transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models

(Submitter supplied) For assessing the cancer-causing potential for humans of a chemical compound, the conventional approach is the use of the 2-year rodent carcinogenicity bioassay, thus alternatives such as in vitro toxicogenomics are highly desired. In the present study, the transcriptomics responses following exposure to genotoxic (GTX) and non-genotoxic (NGTX) hepatocarcinogens and non-carcinogens (NC) in five liver-based in vitro models, namely conventional and epigenetically-stabilized cultures of primary rat hepatocytes, the human hepatoma-derived HepaRG and HepG2 cell lines and the human embryonic stem cell-derived hepatocyte-like cells hES-Heps are examined and compared.

Organism:: Homo sapiens; Rattus norvegicus

Type:: Expression profiling by array

Platforms:: GPL13916 GPL15933
548 Samples

Download data: CEL

Series

Accession:: GSE40117

ID:: 200040117

PubMed Similar studies Analyze with GEO2R

Select item 1000139162.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array [CDF: Brainarray ENSG Version 14.1]

(Submitter supplied) see manufacturer's protocol

Organism:: Homo sapiens

4 Series
1 Related Platform
725 Samples

Download data: TAR

Platform

Accession:: GPL13916

ID:: 100013916

Select item 3009854423.

hES-Heps-MAN control-72h rep3

Organism:: Homo sapiens

Source name:: human embryonic stem cell derived hepatocyte like cells

Platform:: GPL13916
Series:: GSE40117

Download data: CEL

Sample

Accession:: GSM985442

ID:: 300985442

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