GEO DataSet Links for BioProject (Select 103479) - GEO DataSets

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Items: 2

Select item 2000096291.

Comparison of normal and beta catenin deficient kidney gene expression profiles at E12.5

(Submitter supplied) We generated a murine genetic model of beta-catenin deficiency targeted to the ureteric bud cell lineage to study the role of beta-catenin mediated Wnt signaling during ureteric morphogenesis. Keywords: mutation

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS3322
Platform:: GPL1261
6 Samples

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Accession:: GSE9629

ID:: 200009629

Select item 33222.

Beta-catenin deficiency model: kidney

Analysis of embryonic (E12.5) kidneys with beta-catenin deficiency targeted to the ureteric bud cell lineage. Inactivation of beta-catenin leads to abnormal ureteric branching and causes renal aplasia or dysplasia. Results provide insight into the role of beta-catenin during ureteric morphogenesis.