GEO DataSet Links for BioProject (Select 128547) - GEO DataSets

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Items: 2

Select item 2000224341.

Expression data from Evi1-transduced primary bone marrow cells

(Submitter supplied) Evi1 is essential for proliferation of hematopoietic stem cells and implicated in the development of myeloid disorders. Particularly, high Evi1 expression defines one of the largest clusters in acute myeloid leukemia and is significantly associated with extremely poor prognosis. Improvement of the therapeutic outcome of leukemia with activated Evi1 is one of the most challenging issues. However, mechanistic basis of Evi1-mediated leukemogenesis has not been fully elucidated. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS3714
Platform:: GPL1261
8 Samples

Download data: CEL

Series

Accession:: GSE22434

ID:: 200022434

Select item 37142.

Ecotropic viral integration site-1 expression effect on primary bone marrow cells

Analysis of C57BL/6 mononuclear bone marrow cells transduced with ecotropic viral integration site-1 (EVI-1). EVI-1 is one of the dominant oncogenes associated with murine and human myeloid leukemia. Results provide insight into the mechanistic basis of Evi1-mediated leukemogenesis.