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Items: 2

1.

Microarray analysis to identify Egfr-responsive genes

(Submitter supplied) The highly conserved Epidermal Growth Factor-receptor (Egfr) pathway is required in all animals for normal development and homeostasis; consequently, aberrant Egfr signaling is implicated in a number of diseases. Genetic analysis of Drosophila melanogaster Egfr has contributed significantly to understanding this conserved pathway and has led to the discovery of new components and targets. Here we used microarray analysis of Drosophila third instar wing discs, in which Egfr signaling was perturbed, to identify new Egfr-responsive genes. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by array
Dataset:
GDS4496
Platform:
GPL72
6 Samples
Download data: CEL
Series
Accession:
GSE34872
ID:
200034872
2.
Full record GDS4496

Wing disc response to Epidermal Growth Factor Receptor signaling perturbations

Analysis of third instar wing disc from EGFR dominant negative (71B-Gal4; UAS EgfrDN) and EGFR activated (71B-GAL4; UAS EgfrACT) larvae. Aberrant signaling of highly conserved EGFR pathway is implicated in a number of diseases. Results provide insight into the identity of new EGFR-responsive genes.
Organism:
Drosophila melanogaster
Type:
Expression profiling by array, transformed count, 2 genotype/variation sets
Platform:
GPL72
Series:
GSE34872
6 Samples
Download data: CEL

Supplemental Content

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