GEO DataSet Links for BioProject (Select 84527) - GEO DataSets

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Items: 2

Select item 2000001381.

Effect of serotonergic hallucinogen in mouse somatosensory cortex

(Submitter supplied) To investigate the gene program activated by serotonergic hallucinogens in mouse somatosensory cortex, the effects of the 5-HT2A agonist (±)2,5-dimethoxy 4-iodoamphetamine (DOI) on gene expression was studied. The 5-HT2A serotonin receptor is a member of the 5-HT2 receptor subfamily of G protein–coupled receptors. The 5-HT2A receptor is thought to modulate processes related to cognition, appetite, mood, anxiety, sleep, and sexual behavior. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS346
Platform:: GPL226
7 Samples

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Accession:: GSE138

ID:: 200000138

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 3462.

Serotonergic hallucinogen effect in somatosensory cortex

Effect of 5-HT2A seratonin receptor agonist (±)2,5-dimethoxy 4-iodoamphetamine (DOI) in somatosensory cortex. 129Sv mice injected with DOI (2 mg/kg or 10 mg/kg), 1 hour. Abnormal 5-HT2A receptor function implicated in depression and schizophrenia.