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Items: 2

1.

Homocysteine induced alterations in gene expression in neural crest cells

(Submitter supplied) The amino acid homocysteine increases in the serum when there is insufficient folic acid or vitamin B12, or with certain mutations in enzymes important in methionine metabolism. Elevated homocysteine is related to increased risk for cardiovascular and other diseases in adults and elevated maternal homocysteine increases the risk for certain congenital defects, especially those that result from abnormal development of the neural crest and neural tube. more...
Organism:
Gallus gallus
Type:
Expression profiling by array
Dataset:
GDS2646
Platform:
GPL3213
6 Samples
Download data: CEL
Series
Accession:
GSE6868
ID:
200006868
2.
Full record GDS2646

Homocysteine effect on cardiac neural crest cells

Analysis of cultured cardiac neural crest cells treated with homocysteine (HC). Elevated maternal HC increases the risk for congenital defects that result from abnormal development of the neural crest and neural tube. Results provide insight into the molecular basis of HC-induced dysmorphogenesis.
Organism:
Gallus gallus
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL3213
Series:
GSE6868
6 Samples
Download data: CEL
DataSet
Accession:
GDS2646
ID:
2646

Supplemental Content

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