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Links from GEO DataSets

Items: 1 to 20 of 98

1.
Full record GDS1074

AML1-ETO fusion protein effect on CD34+ hematopoietic cells

Analysis of CD34+ hematopoietic cells expressing the AML1-ETO fusion protein which is formed in acute myeloid leukemia (AML) from translocation t(8;21). CD34+ cells isolated from peripheral blood progenitor and cord blood cells. Results provide insight into the role of AML1-ETO in leukemogenesis.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 2 cell type sets
Platform:
GPL8300
Series:
GSE2049
4 Samples
Download data
2.
Full record GDS5208

Dexamethasone effect on epidermal keratinocytes in vitro: time course

Analysis of cultured epidermal keratinocytes treated with the synthetic glucocorticoid (GC) dexamethasone for up to 72 hours. GCs are used as therapeutic agents for skin conditions. Results provide insight into the molecular response of the epidermis to GCs.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 agent, 5 time sets
Platform:
GPL8300
Series:
GSE26487
20 Samples
Download data: CEL
DataSet
Accession:
GDS5208
ID:
5208
3.
Full record GDS4859

Prolactinoma

Analysis of prolactinomas and normal pituitary tissues. Prolactinoma is a benign pituitary tumor that produces excessive prolactin resulting in hyperprolactinemia. Results provide insight into molecular mechanisms underlying the pathogenesis of this pituitary condition.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state sets
Platform:
GPL8300
Series:
GSE36314
7 Samples
Download data: CEL
4.
Full record GDS4417

Inhaled corticotherapy effect on allergic asthma: bronchial biopsies

Analysis of bronchial biopsies from allergic asthma (AA) subjects following inhaled corticosteroids (ICS) therapy. ICS represent potent anti-inflammatory controller medications for the treatment of asthma. Results provide insight into molecular mechanisms underlying the pathophysiology of AA.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 agent, 2 disease state, 2 specimen sets
Platform:
GPL8300
Series:
GSE15823
12 Samples
Download data: CEL
5.
Full record GDS4356

Zaire ebolavirus infection of macrophage: time course

Analysis of primary macrophages from three donors (D1, D2, D3) up to 6 hrs after in vitro exposure to purified Zaire ebolavirus (ZEBOV) virions. ZEBOV is the etiological agent of Ebola Hemorrhagic Fever (EHF). Results provide insight into the initial response of macrophages exposed to Ebola virions.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 individual, 2 infection, 2 time sets
Platform:
GPL8300
Series:
GSE31747
12 Samples
Download data: CEL, CHP
6.
Full record GDS3681

Type 2 diabetes: myotube

Analysis of myotube cell lines established from type 2 diabetes (T2D) subjects. Insulin resistance and reduced mitochondrial biogenesis coexist early in T2D pathogenesis independent of hyperglycemia and obesity. Results provide insight into the effect of T2D on developing skeletal muscle cells.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state sets
Platform:
GPL8300
Series:
GSE12643
20 Samples
Download data: CEL
DataSet
Accession:
GDS3681
ID:
3681
7.
Full record GDS3604

Tamoxifen effect on endometrioid carcinomas

Analysis of endometrial epithelial cells from stage I or II endometrioid carcinomas after treatment with oestrogen or tamoxifen (TMX). Results provide insight into the molecular basis of the association of TMX treatment of breast cancer with an increased incidence of endometrial cancer.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 agent, 2 disease state sets
Platform:
GPL8300
Series:
GSE3013
7 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS3604
ID:
3604
8.
Full record GDS3603

Renal cancer response to rapamycin analog CCI-779 treatment: time course

Expression profiling of peripheral blood mononuclear cells (PBMC) from patients with advanced renal cancer following treatment with the rapamycin analog CCI-779. Gene expression examined 8 and 16 weeks after treatment. Results identify potential gene markers of CCI-779 exposure.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 time sets
Platform:
GPL8300
Series:
GSE1982
79 Samples
Download data
DataSet
Accession:
GDS3603
ID:
3603
9.
Full record GDS3602

Obesity: adipocyte expression profile (HG-U95Av2)

Analysis of cultured abdominal subcutaneous mature adipocytes from 5 male and 5 female non-diabetic obese Pima Indians. The prevalence of obesity in Pima Indians is among the highest of any population. Results provide insight into the role of adipocytes in obesity and obesity-related inflammation.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 disease state, 2 gender sets
Platform:
GPL8300
Series:
GSE2508
20 Samples
Download data
10.
Full record GDS3511

HIV-1 infection effect on macrophages in vitro: time course

Analysis of cultured macrophages for up to 7 days after HIV-1 infection. Macrophages are targets of HIV-1 infection and constitute a viral reservoir that facilitates the spread of HIV-1 to other cells. Results provide insight into the signaling networks affected by HIV-1 infection in macrophages.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 infection, 3 time sets
Platform:
GPL8300
Series:
GSE13395
16 Samples
Download data: CEL
11.
Full record GDS3384

Cyclooxygenase-2 inhibitor celecoxib effect on colorectal adenocarcinoma

Analysis of colorectal adenocarcinomas resected from patients treated with celecoxib for 7 days. Celecoxib is a cycooxygenase-2 inibitor that exhibits anti-cancer activity. Results provide insight into the mechanism of action of celecoxib in vivo.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 agent sets
Platform:
GPL8300
Series:
GSE11237
23 Samples
Download data: CEL
12.
Full record GDS3345

Various mental disorders: postmortem brains

Analysis of postmortem prefrontal cortices from subjects with bipolar disorder, depression, and schizophrenia. Results provide insight into the molecular pathophysiology of these mental disorders.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 4 disease state sets
Platform:
GPL8300
Series:
GSE12654
50 Samples
Download data: CEL
DataSet
Accession:
GDS3345
ID:
3345
13.
Full record GDS3215

13-cis retinoic acid effect on SEB-1 sebocyte cell line

Analysis of cultured sebaceous gland cells (SEB-1 sebocytes) treated with 13-cis retinoic acid (13-cis RA, isotretinoin), a potent acne treatment agent that reduces the size and secretion of sebaceous glands. Results provide insight into the molecular basis for 13-cis RA's acne-clearing effect.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 agent sets
Platform:
GPL8300
Series:
GSE10432
6 Samples
Download data: CEL
14.
Full record GDS3192

Rheumatoid arthritis: synovial macrophages

Analysis of synovial fluid macrophages from 5 patients with rheumatoid arthritis (RA). The chronic inflammation and progressive joint destruction observed in RA are mediated in part by macrophages. Results provide insight into the molecular mechanisms underlying RA pathogenesis.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 disease state sets
Platform:
GPL8300
Series:
GSE10500
8 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS3192
ID:
3192
15.
Full record GDS3175

NF-kappaB and phosphotidylinositol 3-kinase inhibitor treated monocytes infected with the human cytomegalovirus

Analysis of monocytes treated with an NF-kappaB or a phosphatidylinositol 3-kinase (PI3K) inhibitor and then infected with the human cytomegalovirus (HCMV). Results provide insight into the role of NF-kappaB and PI3K in the activation of monocytes to a proinflammatory state after an HCMV infection.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 agent sets
Platform:
GPL8300
Series:
GSE9601
12 Samples
Download data: CEL, CHP
16.
Full record GDS3004

Heat stress effect on an epithelial cell line

Analysis of HEp2 epithelial cells subjected to heat stress at temperatures of 37 to 40 degrees C. Results provide insight into the regulatory pathways that control the response to heat stress.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 5 temperature sets
Platform:
GPL8300
Series:
GSE7458
13 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS3004
ID:
3004
17.
Full record GDS2940

Dendritic cell response to TGF-beta1: time course

Analysis of dendritic cells (DCs) at various time points up to 36 hours following treatment with TGF-beta1. DCs derived from CD34+ hematopoietic progenitor cells induced to differentiate in vitro. Results provide insight into the role of TGF-beta1 in DC development.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 2 cell type, 5 time sets
Platform:
GPL8300
Series:
GSE5178
8 Samples
Download data: CEL
DataSet
Accession:
GDS2940
ID:
2940
18.
Full record GDS2931

Rheumatoid arthritis and osteoarthritis: synovial fibroblasts

Comparison of synovial fibroblasts from patients with rheumatoid arthritis (RA) to those with osteoarthritis (OA). RA is characterized by chronic inflammation and destruction of multiple joints. OA is a degenerative disease resulting from the breakdown of cartilage.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 other sets
Platform:
GPL8300
Series:
GSE7669
12 Samples
Download data: CEL, CHP
19.
Full record GDS2858

Myeloid-related protein 8 and 14 effect on microvascular endothelial cells

Analysis of microvascular endothelial cells (ECs) treated with the myeloid-related protein 8 (MRP8) and 14 (MRP14), proteins that form heterodimers secreted by phagocytes at inflammatory sites. Results provide insight into the role of MRP8 and MRP14 in EC cell death during inflammation.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL8300
Series:
GSE5474
8 Samples
Download data
DataSet
Accession:
GDS2858
ID:
2858
20.
Full record GDS2853

Low and high grade astrocytomas

Comparison of low and high grade astrocytoma brain tumors. Results provide insight into the molecular differences between the two types of tumors.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 disease state, 2 other sets
Platform:
GPL8300
Series:
GSE3185
16 Samples
Download data: CEL
DataSet
Accession:
GDS2853
ID:
2853
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