GEO DataSets

Study of alveolar septation using the Mg-delta strain of fibrillin-1 deficient mice which display an early defect in alveolar septation, and serve as a model for Marfan syndrome and emphysema.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 development stage, 2 genotype/variation sets

Platform:

GPL83

Series:

GSE479

8 Samples

Download data: CEL

Analysis of FACS-sorted, GFP-positive endothelial cells from retinas of postnatal day 8 (P8) homozygous Tie2-GFP transgenics. Deregulated retinal angiogenesis causes vision loss in many ocular diseases. Results provide insight into the molecular mechanisms underlying intraretinal angiogenesis.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 cell type sets

Platform:

GPL83

Series:

GSE27238

6 Samples

Download data: CEL

Analysis of cultured embryonic stem (ES) cells overexpressing the transcription factor STAT3. STAT3 is a downstream target of the LIF signaling cascade. LIF activation maintains ES cells in a pluripotent state. Results provide insight into the role of STAT3 in maintenance of ES cell pluripotency.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 protocol sets

Platform:

GPL83

Series:

GSE11398

6 Samples

Download data: CEL, CHP

Analysis of visual cortices before the critical period for ocular dominance plasticity opens [postnatal day 14 (P14)], at the peak sensitivity of the critical period (P28), and after the critical period (P60). Results provide insight into the molecular mechanisms associated with the critical period.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 3 age sets

Platform:

GPL83

Series:

GSE11764

10 Samples

Download data: CEL, CHP

Analysis of STAT5A and STAT5B depleted pro-B Ba/F3-beta cells stimulated with IL-3 for 0.5 or 2 hours. STAT5A and STAT5B are members of the family of signal transducers and activators of transcription. Results identify IL-3 inducible STAT5 target genes.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 agent, 2 protocol, 3 time sets

Platform:

GPL83

Series:

GSE10389

5 Samples

Download data: CEL, CHP

Analysis of pancreatic tissues from NMRI animals from embryonic day E12.5 to E16.5. Results provide insight into the molecular mechanisms underlying the development of the pancreas.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 5 age sets

Platform:

GPL83

Series:

GSE8070

10 Samples

Download data: CEL

Analysis of left heart ventricles (LV) at various time points up to 48 hours following surgically induced acute myocardial infarction (AMI). Ischemic/infarcted tissue, surviving free wall, and the interventricular septum of LV examined. Results provide insight into the molecular pathogenesis of AMI.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 3 disease state, 7 time, 4 tissue sets

Platform:

GPL83

Series:

GSE4648

66 Samples

Download data: CEL

Analysis of various tissues from animals bearing maternal or paternal uniparental duplications (UpDps) of chromosome 7 regions. Translocation used to produce UpDps proximal and distal to the breakpoint. Results provide insight into the extent and distribution of imprinted genes.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 4 genotype/variation, 4 tissue sets

Platform:

GPL83

Series:

GSE4870

11 Samples

Download data: CEL, EXP

Analysis of embryonic day 14.5 humeri of runt-related transcription factor 2 (Runx2) deficient animals. Runx2 is an essential factor for skeletogenesis and heterozygous loss causes cleidocranial dysplasia. Results provide insight into the molecular mechanisms underlying skeletogenesis.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 genotype/variation sets

Platform:

GPL83

Series:

GSE4911

4 Samples

Download data: CEL, EXP

Analysis of pancreata and submandibular and lacrimal glands from 6-, 9-, and 15-week-old NOD/scid animals, respectively, before the onset of autoimmune destruction of the tissues. The NOD/scid animal is a model for type 1 diabetes. The three organs examined are autoimmune targets in type 1 diabetes.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 3 age, 2 strain, 3 tissue sets

Platform:

GPL83

Series:

GSE4953

39 Samples

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Analysis of spleens from 4-month-old pre-lupus male and female BWF1 animals. The BWF1 strain is a model for systemic lupus erythematosus. BWF1 females are more prone to lupus than BWF1 males.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 gender sets

Platform:

GPL83

Series:

GSE2336

8 Samples

Download data: CEL, EXP

Analysis of lungs of animals exhibiting extremes in airway hyperreactivity, goblet cell metaplasia, or both. Animals were derived from an intercross of an F1 hybrid strain, generated by crossing C57Bl/6J and Balb/cJ strains. Results provide insight into the pathogenesis of complex airway diseases.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 disease state, 2 other sets

Platform:

GPL83

Series:

GSE3925

12 Samples

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Analysis of primary visual cortex (V1) under conditions of binocular deprivation by dark-rearing (DR) or monocular deprivation (MD). Animals subjected to DR from birth till postnatal day (P) 27 or to MD from P11-12 to P27. Results provide insight into the role of visual activity in V1 development.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 3 other, 3 protocol sets

Platform:

GPL83

Series:

GSE4537

12 Samples

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Analysis of positively selected T cell receptor (TCR) transgenic thymocytes from H-2b animals. T lymphocyte development involves TCR-mediated positive selection that ensures the survival of potentially useful T cells. Results provide insight into T lymphocyte development and selection.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 2 genotype/variation sets

Platform:

GPL83

Series:

GSE3909

4 Samples

Download data: CEL, EXP

Analysis of C2C12 myoblast-derived myotubes transduced with transcriptional coactivator PGC-1alpha to induce mitochondrial proliferation in the muscle cells. Cells examined up to 3 days post-transduction. Results combined with other genome-scale datasets to identify mitochondrial proteins.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 3 agent, 4 time sets

Platform:

GPL83

Series:

GSE4330

21 Samples

Download data: CEL

Analysis of three dendritic cell (DC) subpopulations from BALB/c spleens: interferon-producing killer DCs (IKDCs), plasmacytoid DCs (PDCs), and conventional DCs (cDCs). Results identify IKDCs as a distinct DC lineage and provide insight into the role of IKDCs in linking innate and adaptive immunity.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 3 cell type sets

Platform:

GPL83

Series:

GSE3691

6 Samples

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Analysis of FACS-sorted bone cells 7 and 17 days following induction of differentiation. Cells sorted based on GFP expression from a promoter that becomes active in the preosteoblastic stage between days 5 and 7 or from one that remains inactive until the osteoblastic stage between days 15 and 17.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 3 protocol, 2 time sets

Platform:

GPL83

Series:

GSE2332

13 Samples

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Analysis of follicular dendritic cell (FDCs) enriched splenocytes. FDCs are important in the formation of lymphoid germinal centers (GCs), where rapid B-cell proliferation and differentiation occur. Results identify transcripts that are overrepresented in cells associated with FDC networks in GCs.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 cell type sets

Platform:

GPL83

Series:

GSE2123

5 Samples

Download data: CEL

Analysis of pooled mRNA (2, 4, 6 hours) from A.E7 T cell clones activated in conditions that promote (anti-TCR) or inhibit (anti-TCR + CsA or PKCi or Combo) anergy induction. Results identify the early growth response gene 2 (Egr-2) and Egr-3 as key positive regulators of T cell anergy induction.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 5 agent, 3 protocol sets

Platform:

GPL83

Series:

GSE2323

5 Samples

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Expression analysis of spermatogonia, mitotic germ cells of the testis, in 1 week old wild type or Zfp145 (Plzf) knockout. PLZF plays role in maintenance of spermatogonial stem cells.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 genotype/variation sets

Platform:

GPL83

Series:

GSE1399

2 Samples

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