GEO DataSets

Analysis of A549 lung carcinoma and M059K glioblastoma cells treated with dichloroacetate (DCA), an inhibitor of the mitochondrial pyruvate dehydrogenase kinase. DCA shifts metabolism from glycolysis to glucose oxidation and decreases mitochondrial membrane potential in cancer cells.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 agent, 2 cell type sets

Platform:

GPL96

Series:

GSE6014

4 Samples

Download data: CEL

Analysis of peripheral blood-purified CD19-positive B cells activated with CD40. CD40 is a potent activation stimulus for the induction of B cell-mediated antigen presentation and cytokine production. Results provide insight into molecular mechanisms underlying B cell activation via CD40.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 4 individual, 2 protocol sets

Platform:

GPL96

Series:

GSE54017

8 Samples

Download data: CEL

Analysis of synovial tissues from patients with rheumatoid arthritis or osteoarthritis. Results used to generate rule-based classifiers to distinguish patients with rheumatoid arthritis from those with osteoarthritis.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 3 disease state sets

Platform:

GPL96

Series:

GSE55457

33 Samples

Download data: CEL

Analysis of synovial tissues from patients with rheumatoid arthritis or osteoarthritis. Results used to generate rule-based classifiers to distinguish patients with rheumatoid arthritis from those with osteoarthritis.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 disease state sets

Platform:

GPL96

Series:

GSE55584

16 Samples

Download data: CEL

Analysis of synovial tissues from patients with rheumatoid arthritis or osteoarthritis. Results used to generate rule-based classifiers to distinguish patients with rheumatoid arthritis from those with osteoarthritis.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 3 disease state sets

Platform:

GPL96

Series:

GSE55235

30 Samples

Download data: CEL

Comparison of alvelolar macrophages (AMs) of allergic asthma (AA) patients and healthy subjects. AMs are the main immune cells in the airway lumen and are in direct contact with exogenous agents. Results provide insight into the differences between the AMs of AA patients and healthy individuals.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state sets

Platform:

GPL96

Series:

GSE22528

10 Samples

Download data: CEL

Analysis of MCF-7 breast cancer (BC) cells depleted for ERK5 then treated with 17β-estradiol. Increased kinase activity is associated with a poorer outcome for BC patients. Results provide insight into the interplay between estrogen receptor and protein kinase pathways to regulate BC aggressiveness

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 agent, 2 genotype/variation sets

Platform:

GPL96

Series:

GSE53394

8 Samples

Download data: CEL

Analysis of lung fibroblasts isolated from biopsies, taken at the time of diagnosis, from patients with well-defined pulmonary fibrosis associated with systemic sclerosis (SSc-ILD). Results provide insight into the molecular mechanisms underlying the fibrotic fibroblast phenotype in SSc-ILD.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 3 disease state sets

Platform:

GPL96

Series:

GSE40839

21 Samples

Download data: CEL

Analysis of rectal mucosal epithelia from cystic fibrosis patients homozygous for the three-base-pair deletion c.1521_1523delCTT (p.Phe508del, F508del) in the cystic fibrosis transmembrane conductance regulator (CFTR). Results provide insight into molecular mechanisms underlying CF.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 disease state sets

Platform:

GPL96

Series:

GSE15568

29 Samples

Download data: CEL

Analysis of oral squamous cell carcinoma (OSCC)-derived cell lines. OSCC is a lethal disease with early death typically occurring as a result of local invasion and regional lymph node metastases. Results provide insight the molecular mechanisms underlying OSCC.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 9 cell line sets

Platform:

GPL96

Series:

GSE31853

9 Samples

Download data: CEL, CHP

Analysis of whole blood from Huntington’s disease (HD) patients and age- and sex-matched healthy controls. To date, a robust and clinically useful blood test for HD has not been developed. Results provide insight into blood biomarkers for HD activity.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 12 age, 2 disease state, 2 gender, 14 individual sets

Platform:

GPL96

Series:

GSE24250

14 Samples

Download data: CEL

Analysis of colorectal adenocarcinomas with microsatellite instability (MSI CRCs). MSI, caused by defects in the mismatch repair system, is observed in a subset of CRCs. Results provide insight into molecular mechanisms contributing to MSI CRC development.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state sets

Platform:

GPL96

Series:

GSE24514

49 Samples

Download data: CEL, CHP

Analysis of AML blasts displaying aberrant cytoplasmic localization of nucleophosmin (NPMc+ AML) but negative for AML-associated chromosomal translocations. Results provide insight into the validity of the putative predictors of NPM status identified by the training set.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 genotype/variation sets

Platform:

GPL96

Series:

GSE34860

39 Samples

Download data: CEL

Analysis of AML blasts displaying aberrant cytoplasmic localization of nucleophosmin (NPMc+ AML) but negative for AML-associated chromosomal translocations. Results provide insight into putative predictors of NPM status.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 genotype/variation sets

Platform:

GPL96

Series:

GSE34860

39 Samples

Download data: CEL

Analysis of bronchial biopsies from allergic asthma (AA) subjects. These results, together with those from GDS4417 (a study with similar specimen collection procedures, but different subjects, GeneChips, data processing), provide insight into molecular mechanisms underlying AA pathophysiology.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state sets

Platform:

GPL96

Series:

GSE41649

8 Samples

Download data: CEL

Temporal analysis of MOLT-4 leukemia cells treated with 10 ug/mL anti-CD47 dimer MABL (S-S diabody). Cell surface antigen CD47 ligation induces apoptosis in B-chronic lymphocytic leukemia. Results provide insight into the molecular mechanism of CD47-mediated apoptosis in lymphoid malignant cells.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 5 time sets

Platform:

GPL96

Series:

GSE16494

10 Samples

Download data: CEL

Analysis of freshly isolated lymphocyte (CD4+ T cells and CD19+ B cells) and CD33+ myeloid subsets from the blood of Systemic Lupus Erythematosus (SLE) patients. Results provide insight into the molecular mechanisms underlying SLE pathogenesis.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 3 cell type, 2 disease state sets

Platform:

GPL96

Series:

GSE10325

67 Samples

Download data: CEL

Analysis of peripheral blood B cells isolated from 41 untreated chronic lymphocytic leukemia (CLL) patients and 11 age-matched control subjects. B-cell CLL is the most common type of leukemia, mainly affecting adults. Results provide insight into molecular mechanisms underlying CLL pathogenesis.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state sets

Platform:

GPL96

Series:

GSE22529

52 Samples

Download data: CEL

Temporal analysis of PBMCs collected from 25 German relapsing-remitting multiple sclerosis patients treated with recombinant interferon-beta-1b (rIFN-β-1b, 250 µg every other day) for 2 years. Results provide insight into molecular mechanisms of IFN-b action.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 gender, 5 time sets

Platform:

GPL96

Series:

GSE24427

125 Samples

Download data: CEL

Analysis of prostate cancer primary tumors of known disease recurrence status. Results provide insight into the molecular mechanisms underlying recurrent and non-recurrent prostate cancer primary tumors.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 disease state sets

Platform:

GPL96

Series:

GSE25136

79 Samples

Download data: CEL