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Links from GEO DataSets

Items: 1 to 20 of 97

1.
Full record GDS4253

Lung epithelial cells response to lipopolysaccharide exposure

Analysis of laser-microdissected airway epithelial cells from snap-frozen lung 0 and 2 days after lipopolysaccharide (LPS) exposure. Inhalation of LPS can lead to chronic lung diseases like cystic fibrosis and asthma. Results provide insight into inflammatory mediators modulated by LPS exposure.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 time sets
Platform:
GPL85
Series:
GSE36174
6 Samples
Download data: CEL, CHP, TXT
2.
Full record GDS5049

Chronic ethanol ingestion effect on lung alveolar type 2 cell

Analysis of lung alveolar type 2 cells from Sprague-Dawley males following 6 weeks of chronic ingestion of alcohol. The lungs can be irreversibly damaged from chronic alcohol consumption. Results provide insight into the molecular changes in the lung associated with chronic alcohol consumption.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 2 agent sets
Platform:
GPL85
Series:
GSE55243
7 Samples
Download data: CEL
3.
Full record GDS4757

Corticosterone effect on hippocampus: dose response

Analysis of hippocampal CA1 from adrenalectomized F344 males maintained for 3 months with implanted corticosterone (CORT) pellets to produce low or intermediate (glucocorticoid receptor-activating) blood levels of CORT. Results provide insight into the effects of chronic CORT on the hippocampus.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 4 agent, 4 dose, 2 protocol sets
Platform:
GPL85
Series:
GSE37618
39 Samples
Download data: CEL
4.
Full record GDS4625

Dorsal root ganglion in three peripheral neuropathic pain models: time course

Analysis of L4 and L5 dorsal root ganglion (DRGs) up to 40 days post-injury in three distinct peripheral neuropathic pain models: spared nerve injury (SNI), chronic constriction injury (CCI), and spinal nerve ligation injury (SNL). Results provide insight into putative pain modulating genes.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 6 protocol, 5 time sets
Platform:
GPL85
Series:
GSE30691
56 Samples
Download data: CEL
5.
Full record GDS3930

Bone morphogenic protein effect on cultured sympathetic neurons: time course

Analysis of superior cervical ganglia (SCG) cultured neurons treated with bone morphogenic protein-7 (BMP-7) for 6 or 24h. Addition of BMPs triggers these neurons to extend multiple dendrites. Results provide insight into molecular mechanisms underlying initial formation of primary dendrites.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 2 agent, 2 time sets
Platform:
GPL85
Series:
GSE28150
9 Samples
Download data: CEL
6.
Full record GDS3699

Night and day effects on pineal gland (Expt. A)

Analysis of pineal glands from Sprague-Dawley rats at mid-day (Zeitgeber time ZT7) or midnight (ZT19). Rats were kept on a 14:10 light-dark (LD) cycle. The pineal gland plays a vital role in vertebrate chronobiology. Results provide insight into night/day changes in pineal gene expression.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 time sets
Platform:
GPL85
Series:
GSE12341
6 Samples
Download data: CEL
7.
Full record GDS3507

Spinal cord injury effect on the urinary bladder: time course

Analysis of bladders from Sprague-Dawley females for up to 25 days following spinal cord injury (SCI). Bladder wall tissue compliance increases within 2 weeks after SCI in this animal model. Results provide insight into the molecular basis of the changes that the bladder undergoes after SCI.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 disease state, 4 time sets
Platform:
GPL85
Series:
GSE14096
4 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS3507
ID:
3507
8.
Full record GDS3431

Non-alcoholic steatohepatitis model

Analysis of livers from males fed a high polyunsaturated diet containing 70% corn oil to induce the development of non-alcoholic steatohepatitis (NASH). In NASH, steatosis is accompanied by inflammation, necrosis, apoptosis, and fibrosis. Results provide insight into the pathogenesis of NASH.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 disease state sets
Platform:
GPL85
Series:
GSE8253
6 Samples
Download data: CEL, CHP, EXP
DataSet
Accession:
GDS3431
ID:
3431
9.
Full record GDS3189

Follicle stimulating hormone suppression effect on the maturing testis

Analysis of maturing testes from animals suppressed for follicle stimulating hormone (FSH) activity from age 14 to 18 days. FSH activity suppressed by treatment with an antibody to FSH (FSHAb). Results provide insight into the role of FSH in Sertoli and male germ cell development.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL85
Series:
GSE10293
4 Samples
Download data: CEL
DataSet
Accession:
GDS3189
ID:
3189
10.
Full record GDS3180

Estrogen effect on myometrium of ovariectomized females: time course

Analysis of myometria of ovariectomized animals following treatment with estradiol for 6 or 24 hours. Estrogen reduces the increased uterine sympathetic nerve density induced by ovariectomy. Results provide insight into the molecular mechanisms underlying estrogen-modulated sympathetic innervation.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent, 2 time sets
Platform:
GPL85
Series:
GSE9117
4 Samples
Download data: CEL, EXP
11.
Full record GDS3077

Age-related aortic vasculopathy model

Analysis of thoracic aortas (TAs) of Fischer 344/Brown Norway F1 hybrids (F344xBN) at 3 to 28 months of age. Age is a risk factor for vascular disease. The TAs of F344xBN animals exhibit age-related pathologies. Results provide insight into the mechanisms underlying age-mediated vascular pathology.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 4 age sets
Platform:
GPL85
Series:
GSE7281
16 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS3077
ID:
3077
12.
Full record GDS3006

Primordial ovarian follicle development

Analysis of ovaries with unassembled, primordial, and primary follicles. Abnormal primordial follicle development can cause pathologies such as premature ovarian failure. Results provide insight into molecular mechanisms underlying primordial follicle assembly and transition to primary follicles.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 3 development stage, 3 protocol sets
Platform:
GPL85
Series:
GSE9300
6 Samples
Download data: CEL
DataSet
Accession:
GDS3006
ID:
3006
13.
Full record GDS2851

Brain trauma model: time course (RG-U34A)

Analysis of brain at various time points up to 21 days following lateral fluid percussion-induced brain injury. Delayed cell death following trauma results in brain damage. Results provide insight into the mechanisms underlying brain damage after traumatic injury.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 protocol, 7 time sets
Platform:
GPL85
Series:
GSE2392
39 Samples
Download data: CEL
DataSet
Accession:
GDS2851
ID:
2851
14.
Full record GDS2841

Alcohol-preferring inbred strain: brain

Analysis of various CNS regions of inbred alcohol-preferring and non-alcohol preferring animals that have not been exposed to alcohol. Results provide insight into the molecular basis of the difference in alcohol preference between the two strains.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 strain, 5 tissue sets
Platform:
GPL85
Series:
GSE4494
59 Samples
Download data: CEL
15.
Full record GDS2664

Peripheral nerve injury effect on dorsal root ganglion: time course

Analysis of lumbar dorsal root ganglia at various time points up to 50 days following peripheral nerve injury inflicted by either partial sciatic nerve ligation or chronic constriction. Results provide insight into the molecular mechanisms underlying neuropathic pain.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 3 protocol, 3 time sets
Platform:
GPL85
Series:
GSE2636
20 Samples
Download data
DataSet
Accession:
GDS2664
ID:
2664
16.
Full record GDS2468

Soy and whey protein diets effect on colon tumorigenesis

Analysis of colons of soy or whey protein fed Sprague Dawley males 40 weeks after azoxymethane (AOM) injection to induce tumor formation. Lifetime consumption of soy or whey proteins reduces the incidence of AOM-induced colon tumors in rats.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 3 protocol sets
Platform:
GPL85
Series:
GSE6102
9 Samples
Download data: CEL, EXP
17.
Full record GDS2437

L5 spinal nerve ligation model of neuropathic pain: dorsal root ganglion (RG-U34A)

Analysis of L4 and L5 dorsal root ganglia (DRG) from animals 28 and 50 days following L5 spinal nerve ligation. L5 spinal nerve ligation is a model of neuropathic pain.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 protocol, 2 time, 3 tissue sets
Platform:
GPL85
Series:
GSE2884
12 Samples
Download data
DataSet
Accession:
GDS2437
ID:
2437
18.
Full record GDS2385

Targretin, 9-cis retinoic acid, and 4-hydroxyphenylretinamide effect on various organs

Analysis of normal livers, lungs, and mammary glands from Sprague Dawleys treated with targretin (TGR), 9-cis retinoic acid (9cRA), or 4-hydroxyphenylretinamide (4HPR). Results provide insight into the molecular basis of the varying chemopreventive anti-cancer effects of these agents.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 4 agent, 3 tissue sets
Platform:
GPL85
Series:
GSE3952
43 Samples
Download data
DataSet
Accession:
GDS2385
ID:
2385
19.
Full record GDS2311

Estradiol effect on the ischemic brain

Analysis of ischemic cerebral cortices of ovariectomized animals on a regimen of 1 subcutaneous 17beta-estradiol pellet for 1 week. Ischemia was induced by middle cerebral artery occlusion. Results provide insight into the basis of estrogen's protective effect in experimental cerebral ischemia.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL85
Series:
GSE5315
4 Samples
Download data
20.
Full record GDS2268

Ductus arteriosus response to birth and oxygen (RG-U34A)

Analysis of ductus arteriosus (DA) from normoxic and hyperoxic fetuses, and normoxic newborns. Aorta from normoxic fetuses and newborns also examined. Results provide insight into the role of oxygen and the birth process on the initial functional and subsequent permanent closure of DA.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 development stage, 2 protocol, 2 tissue sets
Platform:
GPL85
Series:
GSE3290
5 Samples
Download data
DataSet
Accession:
GDS2268
ID:
2268
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