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Links from GEO DataSets

Items: 9

1.
Full record GDS4319

Conventionalization of germ-free C57BL/6 males: time course

Temporal analysis of colon, ileum, and jejunum from conventionalized males (i.e., germfree mice colonized with total fecal microbiota of their conventionally born and raised siblings). Results provide insight into molecular basis of innate and adaptive immune responses during conventionalization.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 protocol, 7 time, 3 tissue sets
Platform:
GPL11533
Series:
GSE32513
144 Samples
Download data: CEL
2.
Full record GDS6176

Caspase-1 deficiency effect on lipid-loaded intestines

Analysis of the epithelial layer of intestine from Casp1-null, C57BL/6 males 2 hours after an oral lipid bolus. Caspase-1 activates the proinflammatory cytokines IL-1β and IL-18. These results, together with those from GDS4922, provide insight into the role of caspase-1 in lipid metabolism.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 genotype/variation, 3 tissue sets
Platform:
GPL11533
Series:
GSE32515
18 Samples
Download data: CEL
3.
Full record GDS5661

Interleukin 7 and FLT-3 ligand effect on EML1 HSPC line expressing acute lymphoblastic leukemia TEL-AML1 fusion protein: time course

Analysis of TEL-AML1 oncogene-expressing hematopoietic stem/progenitor cell line EML1 treated with interleukin 7 (IL7) and FLT3 ligand (FLT3L) for up to 7 days. IL7 and FLT3L treatment induces B-cell differentiation. Results provide insight into the role of TEL-AML1 in early B-cell differentiation.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation, 2 protocol, 3 time sets
Platform:
GPL11533
Series:
GSE64919
12 Samples
Download data: CEL
DataSet
Accession:
GDS5661
ID:
5661
4.
Full record GDS4922

Caspase-1 deficiency effect on fasted liver

Analysis of liver from Casp1-null, C57BL/6 males in a fasted state. Caspase-1 is a cysteine protease that activates the proinflammatory cytokines IL-1β and IL-18. These results, together with those from GDS6176, provide insight into the role of caspase-1 in lipid metabolism.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 genotype/variation sets
Platform:
GPL11533
Series:
GSE32515
6 Samples
Download data: CEL
5.
Full record GDS4918

Fasting effect on white adipose tissue, liver and skeletal muscle

Analysis of white adipose tissue, liver and skeletal muscle in 24h fasted C57Bl/6J males. Results provide insight into the molecular mechanisms underlying metabolic adaption to food deprivation in various tissues.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 protocol, 3 tissue sets
Platform:
GPL11533
Series:
GSE46495
30 Samples
Download data: CEL
6.
Full record GDS4905

Sparsely or densely ionizing radiation effect on mammary gland: dose response and time course

Analysis of mammary gland from females irradiated at 10 wks of age with varying doses of sparsely or densely ionizing radiation (IR). Mammary tissue collected up to 12 wks post-IR. Results provide insight into molecular response of mammary tissue exposed to different radiation qualities and doses.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 4 dose, 3 stress, 3 time sets
Platform:
GPL11533
Series:
GSE48392
37 Samples
Download data: CEL
DataSet
Accession:
GDS4905
ID:
4905
7.
Full record GDS4878

c-Jun N-terminal kinase-1 deletion effect on bile duct ligation model of liver fibrosis: time course

Analysis of liver from c-Jun N-terminal kinase-1 null (Jnk1-/-) and hepatocyte-specific, JNK1 null (Jnk1Δhepa) males subjected to BDL for up to 28 days to induce liver fibrosis. Liver injury activates Jnk members of the MAPK family. Results provide insight into the role of Jnk1 in liver fibrosis.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 3 genotype/variation, 2 protocol, 2 time sets
Platform:
GPL11533
Series:
GSE40041
24 Samples
Download data: CEL
DataSet
Accession:
GDS4878
ID:
4878
8.
Full record GDS4872

Fasting effect on vanin-1 depleted liver

Analysis of liver from vanin-1 KOs fasted for 24 hrs. Vanin-1 is highly expressed in liver compared to other tissues. In the fasted state, liver switches to fatty acid oxidation and glucose production. Results provide insight into the role of vanin-1 in hepatic lipid metabolism during starvation.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 genotype/variation, 2 protocol sets
Platform:
GPL11533
Series:
GSE51712
16 Samples
Download data: CEL
DataSet
Accession:
GDS4872
ID:
4872
9.
Full record GDS4865

P81S von Hippel-Lindau mutation effect on embryonic stem cell teratomas

Analysis of teratomas from nude mice injected with von Hippel-Lindau (VHL)-deficient mouse ES cells stably expressing human P81S VHL protein. P81S teratomas are resistant to ionizing radiation-induced apoptosis. Results provide insight into molecular mechanisms underlying this adaptive response.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 3 genotype/variation, 2 other sets
Platform:
GPL11533
Series:
GSE37464
10 Samples
Download data: CEL
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