GEO DataSets

Analysis of pulmonary adenocarcinomas (AC). Carcinogen exposure is responsible for the majority of ACs. Results compared with those obtained from a urethane-induced lung tumor model in the mouse (GDS1649), and provide insight into the conserved pathways underlying the development of AC.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 tissue sets

Platform:

GPL8300

Series:

GSE2514

39 Samples

Download data: CEL, EXP

(Submitter supplied) Lung tumors Keywords: other

Organism:

Homo sapiens; Mus musculus

Type:

Expression profiling by array

Datasets:

GDS1649 GDS1650

Platforms:

GPL81 GPL8300

83 Samples

Download data: CEL, EXP

Analysis of lung tumors that develop following treatment with urethane. Urethane-induced lung tumors exhibit similar histological appearance and molecular changes to human pulmonary adenocarcinoma (AC). Results compared with those from human AC (GDS1650).

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 time, 2 tissue sets

Platform:

GPL81

Series:

GSE2514

44 Samples

Download data: CEL, EXP

(Submitter supplied) To identify gene expression biomarkers associated with asbestos-related lung adenocarcinoma, we analyzed primary tumour gene expression for a total of 36 primary lung adenocarcinomas on 22,323 element microarrays, comparing 12 patients with lung asbestos body counts above levels associated with urban dwelling (ARLC-AC: asbestos-related lung cancer-adenocarcinoma) with 24 patients with no asbestos bodies (NARLC-AC: non-asbestos related lung cancer-adenocarcinoma).

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL3877

36 Samples

Download data: TXT

(Submitter supplied) To identify molecular changes that occur during prostate tumor progression, we have characterized a series of prostate cancer cell lines isolated at different stages of tumorigenesis from C3(1)/Tag transgenic mice.

Organism:

Mus musculus; Homo sapiens

Type:

Expression profiling by array

Platform:

GPL20562

19 Samples

Download data: GPR

(Submitter supplied) Gene expression profile of Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP) reveals murine targets for preclinical development of human prostate cancer therapy In this study, we have generated an open source TRAMP microarray dataset to identify differentially expressed genes from human prostate cancer that have concordant expression in TRAMP tumors, and thereby represent lead targets for preclinical therapy development. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

18 Samples

Download data: CEL

(Submitter supplied) Lung cancers are a heterogeneous group of diseases with respect to biology and clinical behavior. So far, diagnosis and classification are based on histological morphology and immunohistological methods for discrimination between two main histologic groups: small cell lung cancer (SCLC) and non-small cell lung cancer which account for 20% and 80% of lung carcinomas, respectively. While SCLCs express properties of neuroendocrine cells, NSCLCs, which are divided into the three major subtypes adenocarcinoma, squamous cell carcinoma and dedifferentiated large cell carcinoma, show different characteristics such as the expression of certain keratins or production of mucin and lack neuroedocrine differentiation. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL201

47 Samples

Download data: CEL

(Submitter supplied) unmatched samples

Organism:

Homo sapiens

Type:

Expression profiling by RT-PCR

Platform:

GPL2845

4 Samples

Download data

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Expression profiling by RT-PCR

Platform:

GPL2845

105 Samples

Download data: TXT

(Submitter supplied) Gene expression differences between between matched tumor and normal samples were analyzed using paired t-test. Keywords: disease state analysis

Organism:

Homo sapiens

Type:

Expression profiling by RT-PCR

Platform:

GPL2845

90 Samples

Download data: TXT

(Submitter supplied) Gene expression differences between the tumor subtypes AC and SCC were analyzed using t-test. Keywords: disease subtype analysis

Organism:

Homo sapiens

Type:

Expression profiling by RT-PCR

Platform:

GPL2845

56 Samples

Download data: TXT

(Submitter supplied) Non-small cell lung cancer (NSCLC) can be classified into the major subtypes adenocarcinoma (AC) and squamous cell carcinoma (SCC) subtypes. Although explicit molecular, histological and clinical characteristics have been reported for both subtypes, no specific therapy exists so far. However, the characterization of suitable molecular targets holds great promises to develop novel therapies in NSCLC. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS3627

Platform:

GPL570

58 Samples

Download data: CEL

Comparison of two non-small cell lung cancer histological subtypes: adenocarcinomas (AC) and squamous cell carcinomas (SCC). Results provide insight into the molecular differences between AC and SCC.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state sets

Platform:

GPL570

Series:

GSE10245

58 Samples

Download data: CEL

(Submitter supplied) It is gradually becoming a new aspect in research to search and explore embryo development for malignant information hidden in tumor cells. In this study, the gene expression profiles for human lungs at four developmental stages and lung adenocarcinoma (ADC) were depicted, respectively. The molecular dynamics was compared for development and lung ADC, and it was proposed that primary lung ADC may hijack part of the molecular mechanisms of lung development to down-regulate homeostasis-associated genes and up-regulate stemness-associated genes; and it was revealed that the genes with monotonely decreasing expression trend during lung development process are enriched with lung ADC prognostic information.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6480

113 Samples

Download data: TXT