GEO DataSets

(Submitter supplied) The mammalian neocortex develops layer organizations with regional differences represented by expression of multiple genes at embryonic stages. These genes could play important roles in the formation of areal cyto-architecture, yet, the number of genes identified so far is not sufficient to explain such intricate processes. Here we collected five regions; the medial, dorsal, lateral, rostral, and occipital, from the dissected E16.5 mouse cerebral cortex and performed extensive gene expression analysis using the Affymetrix U74Av2 array. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS615

Platform:

GPL81

12 Samples

Download data

Analysis of medial, dorsal, lateral, rostral, and occipital regions from strain ICR embryo day 16.5 cerebral cortex provides insight into molecular mechanisms of neocortical area and layer formation.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 6 tissue sets

Platform:

GPL81

Series:

GSE929

12 Samples

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(Submitter supplied) Developmental gene expression profiling of mammalian, fetal orofacial tissue Keywords = orofacial Keywords = embryo Keywords = development Keywords: time-course

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS739

Platform:

GPL81

9 Samples

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Developmental gene expression profiling of fetal orofacial tissue from gestation day (GD) 12-14 embryos.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 3 development stage sets

Platform:

GPL81

Series:

GSE1624

9 Samples

Download data

(Submitter supplied) The cerebral cortex underwent a rapid expansion and complexification during recent primate evolution, but the underlying developmental mechanisms remain essentially unknown. In order to uncover genetic networks underlying the development of the human cerebral cortex, we profiled the transcriptome of human fetal cortical domains containing language areas of Broca and Wernicke, as well as associative areas. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS4532

Platform:

GPL570

8 Samples

Download data: CEL

Analysis of prefrontal/orbito-frontal and parieto-temporal cortex at 17 and 19 gestational weeks. These cortical regions contain presumptive Broca and Wernicke language areas. Results provide insight into molecular mechanisms underlying development of human-specific features of the cerebral cortex.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 development stage, 2 other, 2 tissue sets

Platform:

GPL570

Series:

GSE21858

8 Samples

Download data: CEL

(Submitter supplied) To identify genes heretofore undiscovered as critical players in the biogenesis of teeth, we have used microarray gene expression analysis of the developing mouse molar tooth (DMT) between 1 and 10 days postnatal to identify genes differentially expressed when compared to 16 control tissues (GEO accession # GSE1986). Of the top 100 genes exhibiting increased expression in the DMT, 29 were found to have been previously associated with tooth development. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

4 Samples

Download data: CEL, CHP

(Submitter supplied) The 5HT system is organized into rostral and caudal populations with discrete anatomical locations and opposite axonal trajectories in the developing hindbrain. 5HT neuron cell bodies in the rostral subdivision migrate to the midbrain and pons and extend ascending projections throughout the forebrain. 5HT cell bodies in the caudal subdivision migrate to the ventral medulla and caudal half of the pons and provide descending projections to the brainstem and spinal cord.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

12 Samples

Download data: CEL

(Submitter supplied) Despite the well-established role of the frontal and posterior peri-sylvian cortices in many facets of human-cognitive specializations, including language, little is known about the developmental patterning of these regions in human brain. We performed a genome-wide analysis of human cerebral patterning during mid-gestation, a critical epoch in cortical regionalization. A total of 345 genes were identified as differentially expressed (DE) between superior temporal gyrus (STG) and the remaining cerebral cortex (CTX). more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platforms:

GPL885 GPL96

25 Samples

Download data: CEL, EXP, TXT

(Submitter supplied) The adult mammalian brain is composed of distinct regions that have specialized roles. To dissect molecularly this complex structure, we conducted a project, named the BrainStars (B*) project, in which we sampled ~50 small brain regions, including sensory centers and centers for motion, time, memory, fear, and feeding. To avoid confusion from temporal differences in gene expression, we sampled each region every 4 hours for 24 hours, and pooled the sample sets for DNA-microarray assays. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS3917

Platform:

GPL1261

102 Samples

Download data: CEL

Analysis of 51 regions with distinct functions in the central nervous system (CNS) microdissected from 7 to 8 week-old Balb/c males. Each region sampled every 4 h for 24 h then pooled. Results provide insight into molecular mechanisms underlying distinct functional regions in the adult brain.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 51 tissue sets

Platform:

GPL1261

Series:

GSE16496

102 Samples

Download data: CEL

(Submitter supplied) Many studies have been launched to investigate cellular and molecular regulation regarding human neural system development, yet there is hardly any regional characterization on the whole developmental human cerebral cortex. We found that inhibitory neuron subtypes possibly originated from MGE and CGE. The molecular regulation of excitatory neuron maturation in vivo showed differences to that in rodent. more...

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL20301

51 Samples

Download data: TXT, XLSX

(Submitter supplied) Japanese macaques learn to use rakes to acquire food, and this learning is associated with rapid electrophysiological and morphological changes in the brain. To examine the molecular mechanisms of these plastic changes, we performed comprehensive gene expression analysis with a cDNA microarray and identified many candidate genes.

Organism:

Macaca mulatta; Macaca fuscata

Type:

Expression profiling by array

Platform:

GPL3535

12 Samples

Download data: CEL, CHP

(Submitter supplied) In this study we examined brain gyration using the pig brain as model. Pig cortical tissue from two time points in development representing a non-folded, lissencephalic, brain (embryonic day 60) and primary-folded, gyrencephalic, brain (embryonic day 80) were examined by whole genome expression microarray studies.

Organism:

Sus scrofa

Type:

Expression profiling by array

Platform:

GPL3533

6 Samples

Download data: CEL, CHP