GEO DataSets

(Submitter supplied) Human volunteers were exposed to endotoxin by bronchoscopic instillation, airspace and circulating neutrophils were isolated 16 hours later and compared to circulating neutrophils obtained prior to endotoxin exposure, and to circulating neutrophils exposed to endotoxin in vitro. Keywords = pulmonary inflammantion Keywords = acute lung injury Keywords = acute respiratory distress syndrome Keywords: parallel sample

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS2255

Platform:

GPL96

58 Samples

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Analysis of neutrophils that transmigrate to the alveolar space. Transmigration induced by bronchoscopic instillation of volunteers with endotoxin (LPS). Results identify differences between pulmonary and circulating neutrophils that occur early in endotoxin-induced lung inflammation.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 agent, 3 cell type, 18 individual sets

Platform:

GPL96

Series:

GSE2322

58 Samples

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(Submitter supplied) Neutrophil gene transcription following lipopolysaccharide exposure. Microarray analysis of lipopolysaccharide-treated human neutrophils. Neutrophils respond to infection by degranulation, release of reactive oxygen intermediates, and secretion of chemokines and cytokines; however, activation of neutrophil transcriptional machinery has been little appreciated. Recent findings suggest that gene expression may represent an additional neutrophil function after exposure to lipopolysaccharide (LPS). more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL222

6 Samples

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(Submitter supplied) Gene-expression microarray datasets generated as part of the Immunological Genome Project (ImmGen). Primary cells from multiple immune lineages are isolated ex-vivo, primarily from young adult B6 male mice, and double-sorted to >99% purity. RNA is extracted from cells in a centralized manner, amplified and hybridized to Affymetrix 1.0 ST MuGene arrays. Protocols are rigorously standardized for all sorting and RNA preparation. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL6246

653 Samples

Download data: CEL