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Links from GEO DataSets

Items: 20

1.

Assessment of CcpA-mediated catabolite control of metabolism and enterotoxin production in Bacillus cereus ATCC 14579

(Submitter supplied) In Bacillus cereus the catabolite control protein CcpA was shown to be involved in optimizing the efficiency of glucose catabolism by activating genes encoding glycolytic enzymes including a non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase that mediates conversion of D-glyceraldehyde 3-phosphate to 3-phospho-D-glycerate in one single step, and by repressing genes encoding the citric acid cycle and gluconeogenic enzymes. more...
Organism:
Bacillus cereus ATCC 14579
Type:
Expression profiling by array
Platform:
GPL5161
8 Samples
Download data: TXT
Series
Accession:
GSE7843
ID:
200007843
2.

MGAS5005 vs MGAS5005∆ccpA

(Submitter supplied) The aim of this study was to determine the extent of the CcpA regulon in the M1 serotype MGAS5005. Kinkel and McIver, 2008 Infection and Immunity Keywords: group A streptococcus, CcpA
Organism:
Streptococcus pyogenes
Type:
Expression profiling by array
Platform:
GPL1482
6 Samples
Download data: GPR
Series
Accession:
GSE11328
ID:
200011328
3.

Analysis of the CcpA regulon in Staphylococcus aureus

(Submitter supplied) Background The catabolite control protein A (CcpA) is a member of the LacI/GalR family of transcriptional regulators controlling carbon-metabolism pathways in low-GC Gram positive bacteria. It functions as a catabolite repressor or activator, allowing the bacteria to utilize the preferred carbon source over secondary carbon sources. This study is the first CcpA-dependent transcriptome and proteome analysis in S. more...
Organism:
Staphylococcus aureus subsp. aureus str. Newman; Staphylococcus aureus
Type:
Expression profiling by array
Platform:
GPL3931
6 Samples
Download data
Series
Accession:
GSE12614
ID:
200012614
4.

The Role of CcpA in Gene Regulation in Streptococcus mutans

(Submitter supplied) CcpA is a global regulator of transcription in Gram-positive bacteria that controls gene expression in response to carbohydrate availability. Using the fructan hydrolase (fruA) gene of S. mutans as a model, we demonstrate that CcpA does indeed play a major role in carbohydrate catabolite repression. Using DNA microarrays, the expression of at least 170 genes differed in CcpA-deficient cells compared to the parental strains when cells are grown in the presence of glucose, but only 90 genes showed altered expression when cells were cultivated in the poorly-repressing substrate galactose. more...
Organism:
Streptococcus mutans
Type:
Expression profiling by array
Platform:
GPL4340
16 Samples
Download data: MEV
Series
Accession:
GSE8850
ID:
200008850
5.

Transcriptome comparison between Bacillus cereus ATCC 14579 wildtype (WT), RpoN (Sigma 54) deletion mutant and the complemented strain.

(Submitter supplied) RpoN was shown to have a pleiotropic role in different microorganisms. This study was performed to elucidate role in B. cereus. In this study we compared the transcriptomic profiles of the WT, rpoN mutant and the complemented strain in aerated and static growth conditions.
Organism:
Bacillus cereus ATCC 14579
Type:
Expression profiling by array
Platform:
GPL19768
24 Samples
Download data: TXT
Series
Accession:
GSE65894
ID:
200065894
6.

Comparison of the expression profiles of 630E JIR8094 strain and a ccpA mutant

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Clostridioides difficile
Type:
Expression profiling by array
Platform:
GPL10556
16 Samples
Download data: GPR
Series
Accession:
GSE35152
ID:
200035152
7.

Clostridium difficile mutant ccpA CD630E JIR8094: growth 10h with 0.5% glucose in TY vs growth 10h in TY

(Submitter supplied) transcriptionnal profiling of a ccpA mutant of C. difficile strain JIR8094 comparing growth 10h in 0.5% TY medium with growth 10h in TY medium
Organism:
Clostridioides difficile
Type:
Expression profiling by array
Platform:
GPL10556
8 Samples
Download data: GPR
Series
Accession:
GSE35073
ID:
200035073
8.

Clostridium difficile CD630E JIR8094: growth 10h with 0.5% glucose in TY vs growth 10h in TY

(Submitter supplied) transcriptionnal profiling of a C. difficile strain JIR8094 comparing growth 10h in 0.5% TY medium with growth 10h in TY medium
Organism:
Clostridioides difficile
Type:
Expression profiling by array
Platform:
GPL10556
8 Samples
Download data: GPR
Series
Accession:
GSE35072
ID:
200035072
9.

Comparison of the expression profiles of 630E JIR8094 strain and a ccpA mutant after 10h of growth in TY.

(Submitter supplied) Transcriptionnal profiling of C. difficile 630E JIR8094 strain vs a ccpA mutant after 10h of growth in TY
Organism:
Clostridioides difficile
Type:
Expression profiling by array
Platform:
GPL10556
8 Samples
Download data: GPR
Series
Accession:
GSE35071
ID:
200035071
10.

Comparison of the expression profiles of 630E JIR8094 strain and a ccpA mutant after 10h of growth in TY with 0.5% glucose.

(Submitter supplied) Transcriptionnal profiling of C. difficile 630E JIR8094 strain vs a ccpA mutant after 10h of growth in TY with 0.5% glucose
Organism:
Clostridioides difficile
Type:
Expression profiling by array
Platform:
GPL10556
16 Samples
Download data: GPR
Series
Accession:
GSE35070
ID:
200035070
11.

ccpA Chromatin immunoprecipitation on chip of JIR8094 (CD630E) WT strain and a ccpA mutant after 6h of growth in TY

(Submitter supplied) Comparison of ccpA Chromatine immunoprecipitation on chip using 2 strains : JIR8094 (CD630E) wild type strain and a ccpA mutant after 6h of growth in TYG. This experimental procedure was designed to investigate the consensus binding site, CRE, of pleiotropic regulator ccpA.
Organism:
Clostridioides difficile 630; Clostridioides difficile
Type:
Genome binding/occupancy profiling by array
Platform:
GPL15104
3 Samples
Download data: GPR
Series
Accession:
GSE34971
ID:
200034971
12.

CcpA, a Pleiotropic Key Regulator in Butanol-producing Clostridium acetobutylicum ATCC 824

(Submitter supplied) Clostridium acetobutylicum is a typical bacterium of major importance to industrial butanol production. In order to dissect the regulatory network pertaining to the industrial application of this bacterium, catabolite control protein A (CcpA) was investigated for its global function by DNA microarray.It showed that CcpA of C. acetobutylicum controls hundreds of genes, not only carbon metabolism, but also solvent production and sporulation in the life cycle.The results here demonstrated that CcpA is an important pleiotropic regulator related to some specific physiological and biochemical process in butanol-producing C. more...
Organism:
Clostridium acetobutylicum
Type:
Expression profiling by array
Platform:
GPL14821
8 Samples
Download data: TXT
Series
Accession:
GSE33364
ID:
200033364
13.

High- and low-affinity cre boxes for CcpA binding in Bacillus subtilis revealed by genome-wide analysis

(Submitter supplied) In Bacillus subtilis and its relatives carbon catabolite control, a mechanism enabling to reach maximal efficiency of carbon and energy sources metabolism, is achieved by the global regulator CcpA (carbon catabolite protein A). CcpA in a complex with HPr-Ser-P (seryl-phosphorylated form of histidine-containing protein, HPr) binds to operator sites called catabolite responsive elements, cre. Depending on the cre box position relative to the promoter, the CcpA/HPr-Ser-P complex can either act as a positive or a negative regulator. more...
Organism:
Bacillus subtilis
Type:
Expression profiling by array
Platform:
GPL15025
10 Samples
Download data: TXT
Series
Accession:
GSE35154
ID:
200035154
14.

Analysis of the group A Streptococcus CcpA Transcriptome

(Submitter supplied) This study evaluate how catabolite control protein A (CcpA) inactivation affected gene transcript levels in the group A Streptococcus serotype M1 strain MGAS5005 during growth in standard laboratory medium. Keywords: transcriptome analysis
Organism:
Streptococcus pyogenes; Streptococcus sp. 'group A'
Type:
Expression profiling by array
Platform:
GPL6186
16 Samples
Download data: CEL
Series
Accession:
GSE10156
ID:
200010156
15.

Bacillus subtilis 168 cells: ccpN mutant and ccpN-yqfL double mutant analysis

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Bacillus subtilis; Bacillus subtilis subsp. subtilis str. 168
Type:
Expression profiling by array
Platform:
GPL188
12 Samples
Download data: TXT
Series
Accession:
GSE11937
ID:
200011937
16.

Bacillus subtilis 168 cells: wild-type vs. (ccpN-yqfL) double mutant

(Submitter supplied) Global transcriptional profiling of Bacillus subtilis cells comparing wild-type to a (ccpN-yqfL) double mutant. Abstract of the associated publication (article accepted): The transcriptional regulator CcpN of Bacillus subtilis has been recently characterized as a repressor of two gluconeogenic genes, gapB and pckA, and of a small non-coding regulatory RNA, sr1, involved in arginine catabolism. Deletion of ccpN impairs growth on glucose and strongly alters the distribution of intracellular fluxes, rerouting the main glucose catabolism from glycolysis to the pentose phosphate (PP) pathway. more...
Organism:
Bacillus subtilis; Bacillus subtilis subsp. subtilis str. 168
Type:
Expression profiling by array
Platform:
GPL188
4 Samples
Download data: TXT
Series
Accession:
GSE11876
ID:
200011876
17.

Bacillus subtilis 168 cells: wild-type vs. ccpN (non polar)

(Submitter supplied) Global transcriptional profiling of Bacillus subtilis cells comparing wild-type to a ccpN (yqzB) non polar mutant. Abstract of associated publication (article accepted): The transcriptional regulator CcpN of Bacillus subtilis has been recently characterized as a repressor of two gluconeogenic genes, gapB and pckA, and of a small non-coding regulatory RNA, sr1, involved in arginine catabolism. Deletion of ccpN impairs growth on glucose and strongly alters the distribution of intracellular fluxes, rerouting the main glucose catabolism from glycolysis to the pentose phosphate (PP) pathway. more...
Organism:
Bacillus subtilis; Bacillus subtilis subsp. subtilis str. 168
Type:
Expression profiling by array
Platform:
GPL188
8 Samples
Download data: TXT
Series
Accession:
GSE11873
ID:
200011873
18.

Characterization of PlcRa, a new PlcR-like regulator involved in oxidative stress response and cysteine metabolism during early stationary phase in Bacillus cereus

(Submitter supplied) PlcR, the major virulence transcriptional regulator in the Bacillus cereus group belongs to the RNPP quorum sensor family and is activated through interaction with the secreted heptapeptide PapR7 used as a signalling molecule. We identified using modeling analysis a structural homologue of PlcR, PlcRa, in B. cereus. Whole-genome comparative microarrays identified 119 genes (threshold >3) differentially expressed at the onset of stationary phase in a plcRa mutant. more...
Organism:
Bacillus cereus ATCC 14579
Type:
Expression profiling by array
Platform:
GPL9493
8 Samples
Download data: TXT
Series
Accession:
GSE30514
ID:
200030514
19.

Insight into the response of Bacillus cereus towards the polysaccharide chitosan

(Submitter supplied) Comparison of chitosan-treated B. cereus ATCC 14579 cells with non-treated B. cereus ATCC 14579 cells. 2 chitosans with similar molecular weight (Mw) but different degrees of acetylation (Fa) were used: chitosan B (Mw: 28.4 kDa, Fa: 0.16) (samples 1-3) and chitosan A (Mw: 36.0 kDa, Fa: 0.01) (samples 4-6).
Organism:
Bacillus cereus ATCC 14579; Bacillus cereus
Type:
Expression profiling by array
Platform:
GPL13146
6 Samples
Download data: TXT
Series
Accession:
GSE29024
ID:
200029024
20.

CcpA Ensures Optimal Metabolic Fitness of Streptococcus pneumoniae

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Streptococcus pneumoniae D39
Type:
Expression profiling by array
Platform:
GPL11484
11 Samples
Download data: TXT
Series
Accession:
GSE31819
ID:
200031819
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