GEO DataSets

(Submitter supplied) Hypothalami from Fat (FL) and Lean lines (LL) of juvenile broiler chickens were obtained by divergent selection for high or low levels of abdominal fat at SRA-INRA, France. Gene expression patterns were measured during the development of adiposity at 1 to 7 weeks of age. Differentially expressed genes associated with line, age, or line-by-age were identified. Various phenotypic and metabolic alterations are present between the lines (i.e., abdominal fat, T3 levels and glycemia), however there are no alterations in ad libitum food intake between the lines. more...

Organism:

Gallus gallus

Type:

Expression profiling by array

Platform:

GPL1731

8 Samples

Download data: TXT

(Submitter supplied) Chickens divergently selected for either high abdominal fat content (fat genotype) or low abdominal fat content (lean genotype) at Station Recherches Avicoles, Institut National de la Recherche Agronomique Nouzilly, France were used to profile abdominal fat gene expression at 7 weeks of age. The fat line (FL) and lean line (LL) chickens differ in various phenotypic and metabolic measurements, including abdominal fatness, plasma glycemia and triiodothyronine (T3). more...

Organism:

Gallus gallus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL16133

24 Samples

Download data: TXT

(Submitter supplied) Chickens divergently selected for either high abdominal fat content (fat genotype) or low abdominal fat content (lean genotype) at SRA-INRA, France were used to profile hepatic gene expression during juvenile development (1 to 11 weeks of age) and to identify differentially expressed genes associated with genotype and age. The fat line (FL) and lean line (LL) chickens are different in various phenotypic and metabolic measurements, including abdominal fatness, plasma glycemia and T3. more...

Organism:

Gallus gallus

Type:

Expression profiling by array

Platform:

GPL1731

24 Samples

Download data: GPR

(Submitter supplied) Chickens divergently selected for either high growth (HG genotype) or low growth (LG genotype) at SRA-INRA, France were used to profile abdominal adipose gene expression at 7 wk of age. The HG and LG chickens are different in various phenotypic and metabolic measurements, including growth rate, abdominal fat, plasma glycemia, insulinemia, T4, T3, triglyceride and NEFA. The HG and LG chickens are valuable as a model for biomedical and agricultural traits. more...

Organism:

Gallus gallus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL16133

16 Samples

Download data: DIFF, TXT

(Submitter supplied) Chickens divergently selected for either high growth (HG genotype) or low growth (LG genotype) by F.H. Ricard at SRA-INRA, Nouzilly France were used for time-course transcriptional profiling of abdominal fat during juvenile development (1 to 11 weeks of age) to identify differentially expressed genes. The HG and LG chickens are different in various phenotypic and metabolic measurements, including growth rate, abdominal fat, plasma glycemia, insulinemia, T4, T3, triglyceride and NEFA. more...

Organism:

Gallus gallus

Type:

Expression profiling by array

Platform:

GPL1731

24 Samples

Download data: GPR

(Submitter supplied) Fourty RNA samples from the liver of lean and fat line chickens were organized in 10 pools, 4 by 4 and in the order of chicken adiposity. Expression in these pools were compared Keywords: animals with different genetic background comparison

Organism:

Gallus gallus

Type:

Expression profiling by array

Platform:

GPL3265

28 Samples

Download data

(Submitter supplied) Excessive accumulation of lipids in the adipose tissue is a major problem in the present-day broiler industry. However, few studies have analyzed the expression of adipose tissue genes that are involved in pathways and mechanisms leading to adiposity in chickens. Gene expression profiling of chicken adipose tissue could provide key information about the ontogenesis of fatness and clarify the molecular mechanisms underlying obesity. more...

Organism:

Gallus gallus

Type:

Expression profiling by array

Platform:

GPL3213

10 Samples

Download data: CEL, EXP

(Submitter supplied) Several processes governing growth and metabolism are regulated by the neuroendocrine system, particularly the trophic hormones produced in the anterior pituitary gland. However, many of the differences that exist in pituitary gene expression and functional gene networks associated with divergent growth characteristics are still largely unknown. Using the Del-Mar 14K Chicken Integrated Systems microarray, this experiment evaluated global gene expression in the anterior pituitary gland during the first 7 weeks of post-hatch growth in two lines of chickens genetically selected for high growth (HG) or low growth (LG) at SRA-INRA, France. more...

Organism:

Gallus gallus

Type:

Expression profiling by array

Platform:

GPL1731

31 Samples

Download data: TXT

(Submitter supplied) Gene expression microarray profiling in adult (P180) small litter vs control mice.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL6887

12 Samples

Download data: TXT

(Submitter supplied) Investigate the persistent effects of early postnatal overnutrition on the developmental establishment of the DNA methylation in the mouse hypothalamus.

Organism:

Mus musculus

Type:

Methylation profiling by genome tiling array

Platform:

GPL14637

2 Samples

Download data: TXT

(Submitter supplied) Investigate the genome-wide DNA methylation changes in the mouse hypothalamus during the suckling period.

Organism:

Mus musculus

Type:

Methylation profiling by genome tiling array

Platform:

GPL14637

2 Samples

Download data: TXT

(Submitter supplied) Sprague Dawley rats rendered hypothyroid with 22 days of MMI treatment with half the receiving T3 injection on day 21. Rats killed 24h later and hypothalamic tissue recovered.

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL7294

4 Samples

Download data: TXT

(Submitter supplied) Delayed access to feed following hatching has been associated with reduction in growth performance in chicks. However, the gene networks within the hypothalamus that regulate feed intake and metabolism, and the effects of fasting on those pathways are not well understood. The present experiment evaluated global hypothalamic gene expression in neonatal chicks using the Arizona Gallus gallus 20.7K Oligo Array v1.0 to elucidate genes and pathways regulated by feeding, fasting, and refeeding. more...

Organism:

Gallus gallus

Type:

Expression profiling by array

Platform:

GPL6049

40 Samples

Download data: GPR, TXT

(Submitter supplied) To identify genes selectively expressed in the DMH, we collected RNA samples from four hypothalamic nuclei, namely the Arc, VMH, DMH and LH, using laser microdissection and conducted microarray analysis to compare their gene expression profiles.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL10787

8 Samples

Download data: TXT