GEO DataSets

(Submitter supplied) Transcriptional profiling of Lactobacillus reuteri ATCC 55730 mid-log cultures before vs after exposure to 0.5% bovine bile (oxgall). Two sets of array experiments were performed. One set compared the expression profiles of L. reuteri ATCC 55730 cells before bile exposure vs cells that had been exposed to 0.5% bile for 15 minutes (bile shock). The other set compared the expression profiles of L. reuteri ATCC 55730 cells before bile exposure vs cells that had begun growing again in the presence of 0.5% bile (bile adaptation). more...

Organism:

Limosilactobacillus reuteri

Type:

Expression profiling by array

Platform:

GPL6366

20 Samples

Download data: GPR

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Limosilactobacillus reuteri

Type:

Expression profiling by array

Platforms:

GPL7541 GPL6366

36 Samples

Download data: GPR

(Submitter supplied) Comparison of gene expression between L. reuteri ATCC 55730 in LDMIII between early log phase (T8), late log phase (T12) or early stationary phase phase (T16) or late stationary phase (T24)

Organism:

Limosilactobacillus reuteri

Type:

Expression profiling by array

Platform:

GPL6366

18 Samples

Download data: GPR

(Submitter supplied) Comparison of gene expression between L. reuteri ATCC PTA 6475 in LDMIII between early log phase (T8), late log phase (T12) or early stationary phase phase (T16) or late stationary phase (T24)

Organism:

Limosilactobacillus reuteri

Type:

Expression profiling by array

Platform:

GPL7541

18 Samples

Download data: GPR

(Submitter supplied) Lactobacillus acidophilus NCFM is an industrially important strain used extensively as a probiotic culture. Tolerance of the presence of bile is an attribute important to microbial survival in the intestinal tract. A whole-genome microarray was employed to examine the effects of bile on the global transcriptional profile of this strain, with the intention of elucidating genes contributing to bile tolerance. more...

Organism:

Lactobacillus acidophilus NCFM; Lactobacillus acidophilus

Type:

Expression profiling by array

Platform:

GPL1401

2 Samples

Download data: TXT

(Submitter supplied) Enteric pathogens have developed several resistance mechanisms to survive the antimicrobial action of bile. We investigated the transcriptional profile of Vibrio cholerae O1 El Tor strain C6706 under virulence gene inducing conditions, in the presence and absence of bile. Microarray analysis revealed that the expression of 119 genes was affected by bile. The mRNA levels of genes encoding proteins involved in transport was increased in the presence of bile, whereas mRNA levels of genes encoding proteins involved in pathogenesis and chemotaxis was decreased. more...

Organism:

Vibrio cholerae

Type:

Expression profiling by array

Platform:

GPL4621

12 Samples

Download data: TXT

(Submitter supplied) Comparison of gene expression between L. reuteri DSM 17938 and L. reuteri DSM 17938::pocR mutant grown in semi-defined medium after 24h of growth at 37C in anaerobic condition. PocR is an AraC-like transcriptional regulator, and changes in gene expression between mutant and wild-type strains would indicate genes involved in the PocR regulon.

Organism:

Limosilactobacillus reuteri

Type:

Expression profiling by array

Platform:

GPL6366

6 Samples

Download data: GPR, TXT

(Submitter supplied) The response to bile of Lactobacillus casei BL23 was investigated.

Organism:

Lacticaseibacillus casei; Lacticaseibacillus paracasei ATCC 334

Type:

Expression profiling by array

Platform:

GPL11074

6 Samples

Download data: TXT

(Submitter supplied) The response to bile of Lactobacillus casei BL23 and its derivative strain TC01 was investigated. TC01 strain carries a complete deletion of gene LCABL_02080 which encodes a two component signal transduction response regulator.

Organism:

Lacticaseibacillus paracasei ATCC 334; Lacticaseibacillus casei

Type:

Expression profiling by array

Platform:

GPL11074

12 Samples

Download data: TXT

(Submitter supplied) Bifidobacterium longum is one of the natural inhabitants in human gastrointestinal tract. In order to colonize and exert particular functions in the gut, it has to be tolerant to the physiological concentrations of bile salts. In this work, we used RNA-Seq transcriptomics based on the Next-Generation Sequencing to investigate the global response to bile in B. longum BBMN68, a potential probiotic strain isolated from a healthy centenarian. more...

Organism:

Bifidobacterium longum

Type:

Expression profiling by high throughput sequencing

Platform:

GPL17084

2 Samples

Download data: TXT

(Submitter supplied) Lactobacillus reuteri 100-23 is an autochthonous inhabitant of the rodent gastrointestinal system that adheres to the non-secretory epithelium of the forestomach and forms biofilms. Microarray analysis of the expression profile of L. reuteri 100-23 cells harvested from the stomach of ex-Lactobacillus-free mice, compared to those of L. reuteri 100-23 in laboratory culture, revealed an in vivo upregulation of a urease gene cluster by greater than 50-fold. more...

Organism:

Limosilactobacillus reuteri subsp. rodentium

Type:

Expression profiling by array

Platform:

GPL10986

6 Samples

Download data: TXT

(Submitter supplied) Commensal (symbiont) bacteria form communities in various regions of the bodies of vertebrates. Phylogenetic analysis of gut communities is advanced, but the relationships, especially at the trophic level, between commensals that share gut habitats of monogastric animals have not been investigated to any extent. Lactobacillus reuteri strain 100-23 and Lactobacillus johnsonii strain 100-33 cohabit in the forestomach of mice. more...

Organism:

Limosilactobacillus reuteri subsp. rodentium

Type:

Expression profiling by array

Platform:

GPL10986

4 Samples

Download data: TXT

(Submitter supplied) Recent functional genomics and genome-scale modeling approaches indicated that B12 production in Lactobacillus reuteri could be improved by medium optimization. Here we show that a series of systematic single amino acid omissions could significantly modulate the production of B12 from nearly undetectable levels (by isoleucine omission) to 20-fold higher than previously reported through omission of cysteine. more...

Organism:

Limosilactobacillus reuteri subsp. reuteri F275

Type:

Expression profiling by array

Platform:

GPL7505

13 Samples

Download data: TXT