GEO DataSets

(Submitter supplied) Lactic acid bacteria have been used as starter strains in the production of fermented dairy products for centuries. Lactobacillus acidophilus is a widely recognized probiotic bacteria commonly added to yogurt and used in dietary supplements. In this study, a whole genome microarray was employed to monitor gene expression of L. acidophilus cells propagated in 11% skim milk (SM) during early, mid and late logarithmic phase, and stationary phase. more...

Organism:

Lactobacillus acidophilus; Lactobacillus acidophilus NCFM

Type:

Expression profiling by array

Platform:

GPL1401

6 Samples

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(Submitter supplied) A whole-genome microarray containing 97.4 % of the annotated genes of L. acidophilus was employed to compare genome-wide patterns of transcription at varying pHs between the wild type parent and a histidine protein kinase mutant Keywords: ordered

Organism:

Lactobacillus acidophilus

Type:

Expression profiling by array

Platform:

GPL1401

6 Samples

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(Submitter supplied) L. helveticus is used to modulate cheese flavor and as a starter organism in certain cheese varieties. Our group has compiled a draft (4x) sequence for the 2.4 Mb genome of an industrial strain L. helveticus CNRZ32. The primary aim was to investigate expression of 168 completely sequenced genes during growth in milk and MRS medium using microarrays. Oligonucleotide probes against each of the completely sequenced genes were compiled on maskless photolithography-based DNA microarrays. more...

Organism:

Lactobacillus helveticus; Lactobacillus helveticus CNRZ32

Type:

Expression profiling by array

Platform:

GPL4817

12 Samples

Download data: DATA, PAIR

(Submitter supplied) High-density microarrays based on Maskless Array Synthesizer technology.

Organism:

Lactobacillus helveticus CNRZ32

1 Series

12 Samples

Download data: TXT

(Submitter supplied) Lactobacillus acidophilus NCFM is an industrially important strain used extensively as a probiotic culture. Tolerance of the presence of bile is an attribute important to microbial survival in the intestinal tract. A whole-genome microarray was employed to examine the effects of bile on the global transcriptional profile of this strain, with the intention of elucidating genes contributing to bile tolerance. more...

Organism:

Lactobacillus acidophilus NCFM; Lactobacillus acidophilus

Type:

Expression profiling by array

Platform:

GPL1401

2 Samples

Download data: TXT

(Submitter supplied) L. acidophilus cells, transferred at least five times in modified MRS medium (Barrangou et al, 2003) containing the carbohydrate of interest, were grown to an OD600 of 0.6, harvested and processed for microarray experiments (Azcarate-Peril et al, 2005). Keywords: other

Organism:

Lactobacillus acidophilus

Type:

Expression profiling by array

Platform:

GPL1401

28 Samples

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(Submitter supplied) We used a whole genome array containing 97.4 % of the annotated genes of Lactobacillus acidophilus NCFM, a probiotic culture that belongs to the lactic acid bacteria group, to identify genes that are differentially expressed under several stress conditions. Keywords: Stress response

Organism:

Lactobacillus acidophilus

Type:

Expression profiling by array

Platform:

GPL1401

2 Samples

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(Submitter supplied) The microarray contains 97.4 % of the annotated genes of L. acidophilus NCFM

Organism:

Lactobacillus acidophilus

6 Series

48 Samples

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(Submitter supplied) The Caco-2 epithelial cell line was exposed to the probiotic bacterium L. acidophilus cells for a 1-, 4- or 8-hour exposure time or phosphate-buffered saline (PBS) for 1 hour to study the impact on gene expression levels. The results indicated the effect of exposure time on gene expression levels.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6884

12 Samples

Download data: TXT