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Links from GEO DataSets

Items: 20

1.

Sex- and gonad-biased gene expression in zebrafish

(Submitter supplied) A microarray study of sex- and gonad-biased gene expression was conducted to determine whether zebrafish demonstrate male-specific patterns consistent with those observed in other animals. We identified a large number of genes (5899) demonstrating statistical differences in transcript abundance between male and female Danio rerio. All sex-biases in gene expression were due to differences between testis and ovary, although differences between male and female body likely went undetected due to constraints imposed by study design and statistical criteria. more...
Organism:
Danio rerio
Type:
Expression profiling by array
Platform:
GPL1319
12 Samples
Download data: CEL
Series
Accession:
GSE14979
ID:
200014979
2.

Molecular basis of gender and reproductive status in breeding zebrafish

(Submitter supplied) Sexual reproduction is a complex process involving multiple pathways. In this study, we aimed at investigating gene expression profiles underlying gender specificity in the zebrafish. To do so, we analyzed the transcriptome of the gonads of breeding fish and queried the gene expression profiles for significant differences between the genders and also between stages of gonad development. Major differences in gene expression profiles between genders were encountered at the level of the gonads. more...
Organism:
Danio rerio
Type:
Expression profiling by array
Platform:
GPL4375
11 Samples
Download data: TXT
Series
Accession:
GSE6063
ID:
200006063
3.

Comparative transcriptome analysis of testes and ovaries reveals sex-biased genes and pathways in zebrafish

(Submitter supplied) The goals of this study are to compare the differentially expressed genes between testes and ovaries of zebrafish based on RNA-seq data and some of these genes were validated by qRT–PCR.Further, the differentially expressed genes were devided into up-regulated and down-regulated genes for GO and KEGG analysis.
Organism:
Danio rerio
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24776
2 Samples
Download data: XLS
Series
Accession:
GSE227389
ID:
200227389
4.

Identification of sexually dimorphic gene expression in the brain of adult zebrafish (Danio rerio)

(Submitter supplied) Sexual differentiation in vertebrates is initiated during embryogenesis and leads to the development of individuals into phenotypic males or females. The molecular pathways showing sexual dimorphic patterns have been principally investigated in the gonads. In other organs, much less is known about the gender-associated pattern of gene expression. The brain plays a coordinating role on sexual function in both genders including regulation of reproductive development and maturation through the synthesis of neuropeptide hormones and the regulation of sexual behavior in both males and females. more...
Organism:
Danio rerio
Type:
Expression profiling by array
Platform:
GPL4375
11 Samples
Download data: TXT
Series
Accession:
GSE6853
ID:
200006853
5.

Profiling and comparison of miRNA populations in male and female tissues from Drosophila melanogaster at various stages

(Submitter supplied) By surveying miRNA populations in each sex, we identified sets of miRNAs differentially expressed in male and female tissues across various stages of development.
Organism:
Drosophila melanogaster
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL11203
6 Samples
Download data: TXT
Series
Accession:
GSE57029
ID:
200057029
6.

Neurotranscriptome profiles of four zebrafish strains

(Submitter supplied) Zebrafish is a model system being used in a variety of basic research and biomedical studies. Understanding the neurotranscriptomic architecture will greatly facilitate and enhance interpretation of research projects. Studies have reported that there are strain and sex-specific behavioral variation particulary in response to stress and anxiety-inducing scenarios. Capitalizing on previously documented behavioral variation by strains and sex of zebrafish, this study seeks to understand the neurotranscriptomic mechanisms potentially underlying this variation. more...
Organism:
Danio rerio
Type:
Expression profiling by high throughput sequencing
Platform:
GPL15583
16 Samples
Download data: TXT
Series
Accession:
GSE61108
ID:
200061108
7.

Sexual dimorphic methylation patterns in IL1b and Casp9 in the zebrafish gonads

(Submitter supplied) Sexual dimorphic methylation patterns in IL1b and Casp9 in the zebrafish gonads
Organism:
Danio rerio
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL18413
19 Samples
Download data: CSV, TXT
Series
Accession:
GSE134291
ID:
200134291
8.

Sex-biased gene expression during head development in a sexually dimorphic stalk-eyed fly

(Submitter supplied) Stalk-eyed flies (family Diopsidae) are a model system for studying sexual selection due to the elongated and sexually dimorphic eye-stalks found in many species. These flies are of additional interest because their X chromosome is derived largely from an autosomal arm in other flies. To identify candidate genes required for development of dimorphic eyestalks and investigate how sex-biased expression arose on the novel X we compared gene expression between males and females using oligonucleotide microarrays and RNA from developing eyestalk tissue or adult heads in the dimorphic diopsid, Teleopsis dalmanni. more...
Organism:
Teleopsis dalmanni
Type:
Expression profiling by array
Platform:
GPL15419
42 Samples
Download data: TXT
Series
Accession:
GSE37121
ID:
200037121
9.

Gene expression in sexually differentiating gonads of Xenopus laevis

(Submitter supplied) The aim of this study was to study the gene expression profile in developing female and male gonads of Xenopus laevis at four stages: at the Nieuwkoop-Faber stage 50 (genital ridge), at NF53 (sex-determining period), NF56 (the onset of sexual differentiation), NF62 (gonads sexually differentiated).
Organism:
Xenopus laevis
Type:
Expression profiling by array
Platform:
GPL24136
24 Samples
Download data: TXT
Series
Accession:
GSE105103
ID:
200105103
10.

Dynamics of the transcriptional landscape during human gonad development during fetal life

(Submitter supplied) Fetal life is a crucial period for sexual reproduction when bipotential gonads differentiate into either a testis or an ovary. Gaining insights into the complex molecular events underlying this process is central to a better understanding of disorders of sexual development. The present work therefore intends to improve the knowledge on molecular pathways at play during gonad development in humans using RNA-Sequencing.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16791
48 Samples
Download data: BED, GTF, TXT, XLSX
Series
Accession:
GSE116278
ID:
200116278
11.

Zebrafish gonadal transcriptome analysis in response to heat

(Submitter supplied) High temperature can induce masculinization in many fish species including zebrafish (Ospina-Alvarez & Piferrer PLoS One 3:e2837). Juvenile zebrafish exposed to high temperature during gonad differentiation period will result in male bias adult sex ratio. This experiment compared the zebrafish gonadal transcriptome between fishes that were exposed to high (36 oC) and control (28 oC) temperatures. Gene expression analysis using microarray were performed at juvenile (37 dpf) and adult (90 dpf) stages.
Organism:
Danio rerio
Type:
Expression profiling by array
Platform:
GPL17795
46 Samples
Download data: PAIR
Series
Accession:
GSE51434
ID:
200051434
12.

Toxicogenomics and phenotypic characterization of adult female and zebrafish liver treated with cadmium (II)

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Danio rerio
Type:
Expression profiling by array
Platform:
GPL2715
44 Samples
Download data: TXT
Series
Accession:
GSE41625
ID:
200041625
13.

Toxicogenomics and phenotypic characterization of adult male zebrafish liver treated with cadmium (II)

(Submitter supplied) We performed microarray-based expression profiling on liver of male zebrafish exposed to 30 µg/L of cadmium (II) chloride for 8-96 h, to identify global transcriptional programs and biological pathways involved in cadmium-induced adaptive responses under in vivo environment.
Organism:
Danio rerio
Type:
Expression profiling by array
Platform:
GPL2715
22 Samples
Download data: TXT
Series
Accession:
GSE41623
ID:
200041623
14.

Toxicogenomics and phenotypic characterization of adult female zebrafish liver treated with cadmium (II)

(Submitter supplied) We performed microarray-based expression profiling on liver of female zebrafish exposed to 30 µg/L of cadmium (II) chloride for 8-96 h, to identify global transcriptional programs and biological pathways involved in cadmium-induced adaptive responses under in vivo environment.
Organism:
Danio rerio
Type:
Expression profiling by array
Platform:
GPL2715
22 Samples
Download data: TXT
Series
Accession:
GSE41622
ID:
200041622
15.

Toxicogenomics and phenotypic characterization of adult female zebrafish liver treated with arsenic [As(V)]

(Submitter supplied) We performed microarray-based expression profiling on liver of male zebrafish exposed to 15ppm (~ 192 µM) of arsenic [As(V)] for 8-96 h, to identify global transcriptional programs and biological pathways involved in chloroaniline-induced adaptive responses under in vivo environment.
Organism:
Danio rerio
Type:
Expression profiling by array
Platform:
GPL2715
24 Samples
Download data: TXT
Series
Accession:
GSE30062
ID:
200030062
16.

Toxicogenomics and phenotypic characterization of adult female zebrafish liver treated with nitrophenol

(Submitter supplied) We performed microarray-based expression profiling on liver of male zebrafish exposed to 7 mg/L of nitrophenol for 8-96 h, to identify global transcriptional programs and biological pathways involved in chloroaniline-induced adaptive responses under in vivo environment.
Organism:
Danio rerio
Type:
Expression profiling by array
Platform:
GPL2715
24 Samples
Download data: TXT
Series
Accession:
GSE30060
ID:
200030060
17.

Toxicogenomics and phenotypic characterization of adult male zebrafish liver treated with nitrophenol

(Submitter supplied) We performed microarray-based expression profiling on liver of male zebrafish exposed to 7 mg/L of nitrophenol for 8-96 h, to identify global transcriptional programs and biological pathways involved in chloroaniline-induced adaptive responses under in vivo environment.
Organism:
Danio rerio
Type:
Expression profiling by array
Platform:
GPL2715
24 Samples
Download data: TXT
Series
Accession:
GSE30058
ID:
200030058
18.

Toxicogenomics and phenotypic characterization of adult female zebrafish liver treated with chloroaniline

(Submitter supplied) We performed microarray-based expression profiling on liver of male zebrafish exposed to 30 µg/L of chloroaniline for 8-96 h, to identify global transcriptional programs and biological pathways involved in chloroaniline-induced adaptive responses under in vivo environment.
Organism:
Danio rerio
Type:
Expression profiling by array
Platform:
GPL2715
24 Samples
Download data: TXT
Series
Accession:
GSE30057
ID:
200030057
19.

Toxicogenomics and phenotypic characterization of adult male zebrafish liver treated with chloroaniline

(Submitter supplied) We performed microarray-based expression profiling on liver of male zebrafish exposed to 30 µg/L of chloroaniline for 8-96 h, to identify global transcriptional programs and biological pathways involved in chloroaniline-induced adaptive responses under in vivo environment.
Organism:
Danio rerio
Type:
Expression profiling by array
Platform:
GPL2715
24 Samples
Download data: TXT
Series
Accession:
GSE30055
ID:
200030055
20.

Trancriptome Kinetics of Arsenic-induced Adaptive Response in Zebrafish Liver.

(Submitter supplied) In this study, we performed microarray-based expression profiling on liver of zebrafish exposed to 60 mg/L (192?M) arsenic [As(V)] for 8-96 h, to identify global transcriptional programs and biological networks involved in arsenic-induced adaptive responses in vivo. We identified temporal differentially-expressed gene sets which we have grouped into early, late and all-time arsenic-responsive gene sets. more...
Organism:
Danio rerio
Type:
Expression profiling by array
Dataset:
GDS2249
Platform:
GPL2715
24 Samples
Download data
Series
Accession:
GSE3048
ID:
200003048
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