GEO DataSets

(Submitter supplied) Differences in the selective pressures experienced by males and females are believed to be ubiquitous in dioecious organisms and are expected to result in the evolution of sexually antagonistic alleles, thereby driving the evolution of sexual dimorphism. Negative genetic correlation for fitness between the sexes has been documented, however, the identity, number and location of loci causing this relationship are unknown. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL1322

120 Samples

Download data: CEL

(Submitter supplied) Five different mitochondrial strains were introgressed in male and female fruit flies with identical (w1118) nuclear genetic background.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL1322

40 Samples

Download data: CEL, CSV, TXT

(Submitter supplied) Intralocus sexual conflict, where males and females have different fitness optima for the same trait, has been suggested to potentially be resolved by genomic imprinting, whereby expression in offspring is altered according to parent-of-origin. However, this idea has not yet been empirically tested. Here, we designed an experimental evolution protocol in Drosophila melanogaster which enabled us to look for imprinting effects on the X-chromosome. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL1322

18 Samples

Download data: CEL

(Submitter supplied) A number of genes associated with sexual traits and reproduction evolve at the sequence level faster than the majority of genes coding for non-sex-related traits. Whole genome analyses allow this observation to be extended beyond the limited set of genes that have been studied thus far. We use cDNA microarrays to demonstrate that this pattern holds in Drosophila for the phenotype of gene expression as well, but in one sex only. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Datasets:

GDS438 GDS439 GDS440 GDS441

Platform:

GPL356

23 Samples

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(Submitter supplied) 5928 cDNAs from the Drosophila Gene Collection version 1.0 were amplified by PCR with universal primers and PCR products were confirmed by gel electrophoresis. Added to these was a set of 177 separately amplified controls, each of which was replicated from one to 16 times on the array. Clones for which the PCR product was absent, faint, the incorrect size, or showed multiple bands failed PCR quality control. more...

Organism:

Drosophila melanogaster

4 DataSets

3 Series

56 Samples

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Analysis of intraspecific expression differentiation shows that gene expression in males evolves more rapidly than in females. Canton S, Oregon R, Hikone R, a St. Louis-derived isofemale strain and four Zimbabwe-derived lines examined.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, log ratio, 5 strain sets

Platform:

GPL356

Series:

GSE539

5 Samples

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Analysis of intraspecific expression differentiation shows that gene expression in males evolves more rapidly than in females. Canton S, Oregon R, Hikone R, a St. Louis-derived isofemale strain and four Zimbabwe-derived lines examined.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, log ratio, 6 strain sets

Platform:

GPL356

Series:

GSE539

6 Samples

Download data

Analysis of intraspecific expression differentiation shows that gene expression in males evolves more rapidly than in females. Canton S, Oregon R, Hikone R, a St. Louis-derived isofemale strain and four Zimbabwe-derived lines examined.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, log ratio, 7 strain sets

Platform:

GPL356

Series:

GSE539

7 Samples

Download data

Analysis of intraspecific expression differentiation shows that gene expression in males evolves more rapidly than in females. Canton S, Oregon R, Hikone R, a St. Louis-derived isofemale strain and four Zimbabwe-derived lines examined.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, log ratio, 6 strain sets

Platform:

GPL356

Series:

GSE539

6 Samples

Download data

(Submitter supplied) Many multi-exon genes are subject to alternative splicing, which is thought to increase phenotypic complexity by allowing a single locus to produce multiple functionally distinct proteins. However, genetic and developmental variation in alternative splicing has never been examined systematically. We therefore undertook a genome-wide analysis of sex- and genotypic-specific splicing in Drosophila in conjunction with sex- and line-specific transcription. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL3809

50 Samples

Download data: TXT

(Submitter supplied) Species-specific regulation of gene expression contributes to the development and maintenance of reproductive isolation and to species differences in ecologically important traits. A better understanding of the evolutionary forces which shape regulatory variation and divergence can be developed by comparing expression differences among species and interspecific hybrids. Once expression differences are identified, the underlying genetics of regulatory variation or divergence can be explored. more...

Organism:

Drosophila simulans; Drosophila melanogaster; Drosophila sp. (in: flies)

Type:

Expression profiling by genome tiling array

Platform:

GPL5919

24 Samples

Download data: BAR, CEL

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL6799

88 Samples

Download data: GPR

(Submitter supplied) Drosophila melanogaster undergoes a complete metamorphosis, during which time the larval male and female forms transition into sexually dimorphic, reproductive adult forms. To understand this complex morphogenetic process at a molecular-genetic level, we performed whole genome microarray analyses. Genes were identified that were expressed during metamorphosis in both somatic and germline tissues of males and females. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL6799

60 Samples

Download data: GPR

(Submitter supplied) Drosophila melanogaster undergoes a complete metamorphosis, during which time the larval male and female forms transition into sexually dimorphic, reproductive adult forms. To understand this complex morphogenetic process at a molecular-genetic level, we performed whole genome microarray analyses. In somatic tissues at 48 hour After Puparium Formation (APF), 173 sex-biased transcripts that likely function downstream of the doublesex (dsx) branch of the sex determination hierarchy were identified. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL6799

28 Samples

Download data: GPR

(Submitter supplied) Genes with sex-biased expression often show rapid molecular evolution between species. Previous population genetic and comparative genomic studies of Drosophila melanogaster and D. simulans revealed that male-biased genes have especially high rates of adaptive evolution. To test if this is also the case for other lineages within the melanogaster group, we investigated gene expression in D. ananassae, a species that occurs in structured populations in tropical and subtropical regions. more...

Organism:

Drosophila ananassae

Type:

Expression profiling by array

Platform:

GPL9699

12 Samples

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(Submitter supplied) Wild-type laboratory strains of model organisms are typically kept in isolation for many years, with the action of genetic drift and selection on mutational variation causing lineages to diverge with time. Natural populations from which such strains are established, show that gender-specific interactions in particular drive many aspects of sequence level and transcriptional level variation. Here, our goal was to identify genes that display transcriptional variation between laboratory strains of Drosophila melanogaster, and to explore evidence of gender-biased interactions underlying that variability. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Dataset:

GDS3639

Platform:

GPL72

29 Samples

Download data: CEL

Analysis of male and female flies of 5 wild-type laboratory strains. Results provide insight into the extent to which transcriptional variation is inherent in commonly used laboratory strains and the relationship of variation in gene expression to sexual dimorphism.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array, transformed count, 2 gender, 5 strain sets

Platform:

GPL72

Series:

GSE9149

29 Samples

Download data: CEL

(Submitter supplied) Investigatation into how genes with sex-differential expression profiles are distributed among the chromosomes in Drosophila. Assayed the expression of 14,142 predicted transcripts in competitive hybridizations and found a dramatic underrepresentation of X-chromosome genes showing high relative expression in male. This is the first report of sex-biased expression of the full (predicted) genome. Findings indicate that there is significant sex-biased expression, especially in gonads. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL20

46 Samples

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(Submitter supplied) In Drosophila melanogaster, mating radically transforms female physiology and behavior. Post-mating responses include an increase in the oviposition rate, a reduction in female receptivity, and an activation of the immune system . The fitness consequences of mating are similarly dramatic – females must mate once in order to produce fertile eggs, but additional matings have a clear negative effect. Previously, microarrays have been used to examine gene expression of females differing in their reproductive status with the aim of identifying genes influenced by mating. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL1322

12 Samples

Download data: CEL

(Submitter supplied) We used RNA-seq to investigate gene expression variation in Malpighian tubules, which have a function analogous to that of human kidneys. In order to characterize population differentiation, we sequenced the Malpighian tubule transcriptomes of flies derived from two populations, one from sub-Saharan Africa (Zimbabwe) and one from Europe (the Netherlands). Males and females were examined separately. Overall, we found a high amount of differential expression between sexes (2,308 genes) and populations (2,474 genes). Although most of the differentially expressed genes were consistent between sexes and populations, there were 615 genes showed sex-biased expression in only one population and 557 genes showed population-biased expression in only one sex.

Organism:

Drosophila melanogaster

Type:

Expression profiling by high throughput sequencing

Platform:

GPL13304

8 Samples

Download data: TXT