GEO DataSets

(Submitter supplied) Species-specific regulation of gene expression contributes to the development and maintenance of reproductive isolation and to species differences in ecologically important traits. A better understanding of the evolutionary forces which shape regulatory variation and divergence can be developed by comparing expression differences among species and interspecific hybrids. Once expression differences are identified, the underlying genetics of regulatory variation or divergence can be explored. more...

Organism:

Drosophila melanogaster; Drosophila sp. (in: flies); Drosophila simulans

Type:

Expression profiling by genome tiling array

Platform:

GPL5919

24 Samples

Download data: BAR, CEL

(Submitter supplied) Expression profile comparison of females of D. melanogaster, D. simulans and their hybrid. RNA source: whole body. Keywords: other

Organism:

Drosophila melanogaster; Drosophila simulans

Type:

Expression profiling by array

Platform:

GPL356

21 Samples

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(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Drosophila melanogaster; Drosophila mauritiana; Drosophila sechellia; Drosophila simulans; Drosophila sechellia x Drosophila simulans; Drosophila simulans x Drosophila mauritiana

Type:

Expression profiling by array

Platforms:

GPL4022 GPL3829

128 Samples

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(Submitter supplied) Species often produce sterile hybrids early in their evolutionary divergence, and some evidence suggests that hybrid sterility may be associated with deviations or disruptions in gene expression. In support of this idea, many studies have shown that a high proportion of male-biased genes are underexpressed compared to non-sex-biased genes in sterile F1 male hybrids of Drosophila species. In this study, we examined and compared patterns of misexpression in 4 day old sterile male F1 hybrids of Drosophila simulans and its sibling species, D. more...

Organism:

Drosophila melanogaster; Drosophila sechellia; Drosophila simulans; Drosophila sechellia x Drosophila simulans

Type:

Expression profiling by array

Platform:

GPL3829

22 Samples

Download data

(Submitter supplied) Species often produce sterile hybrids early in their evolutionary divergence, and some evidence suggests that hybrid sterility may be associated with deviations or disruptions in gene expression. In support of this idea, many studies have shown that a high proportion of male-biased genes are underexpressed compared to non-sex-biased genes in sterile F1 male hybrids of Drosophila species. In this study, we examined and compared patterns of misexpression in 4 day old sterile male F1 hybrids of Drosophila simulans and its sibling species, D. more...

Organism:

Drosophila simulans x Drosophila mauritiana; Drosophila simulans; Drosophila melanogaster; Drosophila mauritiana

Type:

Expression profiling by array

Platform:

GPL3829

22 Samples

Download data

(Submitter supplied) Species often produce sterile hybrids early in their evolutionary divergence, and some evidence suggests that hybrid sterility may be associated with deviations or disruptions in gene expression. In support of this idea, many studies have shown that a high proportion of male-biased genes are underexpressed compared to non-sex-biased genes in sterile F1 male hybrids of Drosophila species. In this study, we examined and compared patterns of misexpression in 4 day old sterile male F1 hybrids of Drosophila simulans and its sibling species, D. more...

Organism:

Drosophila sechellia; Drosophila mauritiana; Drosophila simulans; Drosophila sechellia x Drosophila simulans

Type:

Expression profiling by array

Platform:

GPL4022

22 Samples

Download data

(Submitter supplied) Species often produce sterile hybrids early in their evolutionary divergence, and some evidence suggests that hybrid sterility may be associated with deviations or disruptions in gene expression. In support of this idea, many studies have shown that a high proportion of male-biased genes are underexpressed compared to non-sex-biased genes in sterile F1 male hybrids of Drosophila species. In this study, we examined and compared patterns of misexpression in 4 day old sterile male F1 hybrids of Drosophila simulans and its sibling species, D. more...

Organism:

Drosophila sechellia; Drosophila simulans x Drosophila mauritiana; Drosophila simulans; Drosophila mauritiana

Type:

Expression profiling by array

Platform:

GPL4022

22 Samples

Download data

(Submitter supplied) Species often produce sterile hybrids early in their evolutionary divergence, and some evidence suggests that hybrid sterility may be associated with deviations or disruptions in gene expression. In support of this idea, many studies have shown that a high proportion of male-biased genes are underexpressed compared to non-sex-biased genes in sterile F1 male hybrids of Drosophila species. In this study, we examined and compared patterns of misexpression in F1 hybrid male third instar larvae of Drosophila simulans and its sibling species, D. more...

Organism:

Drosophila sechellia; Drosophila simulans; Drosophila sechellia x Drosophila simulans; Drosophila mauritiana

Type:

Expression profiling by array

Platform:

GPL4022

22 Samples

Download data

(Submitter supplied) Species often produce sterile hybrids early in their evolutionary divergence, and some evidence suggests that hybrid sterility may be associated with deviations or disruptions in gene expression. In support of this idea, many studies have shown that a high proportion of male-biased genes are underexpressed compared to non-sex-biased genes in sterile F1 male hybrids of Drosophila species. In this study, we examined and compared patterns of misexpression in F1 hybrid male third instar larvae of Drosophila simulans and its sibling species, D. more...

Organism:

Drosophila sechellia; Drosophila simulans; Drosophila simulans x Drosophila mauritiana; Drosophila mauritiana

Type:

Expression profiling by array

Platform:

GPL4022

22 Samples

Download data

(Submitter supplied) In order to test the hypothesis that adult hybrid misexpression results from the cascading effect of earlier-expressed developmentally important improperly regulated genes, as well as address whether Von Baer’s 3rd law (suggesting that earlier stages of development should be more similar between species than later stages) holds at the level of gene expression, we conducted whole-transcriptome Drosophila melanogaster cDNA microarray-based expression profiling of males of D. more...

Organism:

Drosophila melanogaster; Drosophila sechellia; Drosophila simulans; Drosophila sechellia x Drosophila simulans

Type:

Expression profiling by array

Dataset:

GDS3835

Platform:

GPL3598

48 Samples

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Analysis of males of 3 species (melanogaster, sechellia, simulans) and D. sechellia x D. simulans F1 hybrids during 4 developmental stages. Results within and between pure species and hybrids provide insight into both the evolution of gene regulation in the context of development and speciation.

Organism:

Drosophila melanogaster; Drosophila sechellia; Drosophila simulans; Drosophila sechellia x Drosophila simulans

Type:

Expression profiling by array, log2 ratio, 4 development stage, 4 species sets

Platform:

GPL3598

Series:

GSE17535

48 Samples

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(Submitter supplied) RNA was extracted from adult male and adult female Drosophila simulans carrying small genomic segments introgressed from Drosophila mauritiana

Organism:

Drosophila melanogaster; Drosophila mauritiana; Drosophila simulans

Type:

Expression profiling by array

Platform:

GPL6056

64 Samples

Download data: GPR, TXT

(Submitter supplied) Using RNA-seq technology, a comprehensive assessment of cis regulatory divergence in interspecific hybrid female heads was conducted and patterns of sequence evolution (Begun et al. 2007) within causal loci were examined. Genotype specific references were shown to virtually eliminate the map bias plaguing this technology. A novel Bayesian model, which uses allele representation in F1 hybrid DNA sequence reads as a prior, was used to estimate allele frequencies in RNA sequences.

Organism:

Drosophila melanogaster x Drosophila simulans

Type:

Expression profiling by high throughput sequencing

Platform:

GPL15045

3 Samples

Download data: CSV

(Submitter supplied) These data were generated in a study to analyze the genetic causes of gene regulatory divergence. mRNA-seq libraies were prepared from poly(A)+ RNA prepared from whole F1 hybrids of D. melanogaster and D. sechellia (female 0-3d post eclosion, "D_mel_x_D_sec"). A mixed mRNA- seq library was prepared from D. melanogaster and D. sechellia poly(A) + RNA (mixed before library preparation, "D_mel_+_D_sec). more...

Organism:

Drosophila sechellia; Drosophila melanogaster x Drosophila sechellia; Drosophila melanogaster

Type:

Expression profiling by high throughput sequencing

4 related Platforms

4 Samples

Download data: BED

(Submitter supplied) http://www.nature.com/ng/journal/v33/n2/abs/ng1086.html. Little is known about broad patterns of variation and evolution of gene expression during any developmental process. Here we investigate variation in genome-wide gene expression among Drosophila simulans, Drosophila yakuba and four strains of Drosophila melanogaster during a major developmental transition?the start of metamorphosis. Differences in gene activity between these lineages follow a phylogenetic pattern, and 27% of all of the genes in these genomes differ in their developmental gene expression between at least two strains or species. more...

Organism:

Drosophila melanogaster; Drosophila simulans; Drosophila yakuba

Type:

Expression profiling by array

5 related Platforms

48 Samples

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(Submitter supplied) Little is known about broad patterns of variation and evolution of gene expression during any developmental process. Here we investigate variation in genome-wide gene expression among Drosophila simulans, Drosophila yakuba and four strains of Drosophila melanogaster during a major developmental transition-the start of metamorphosis. Differences in gene activity between these lineages follow a phylogenetic pattern, and 27% of all of the genes in these genomes differ in their developmental gene expression between at least two strains or species. more...

Organism:

Drosophila melanogaster; Drosophila simulans; Drosophila yakuba

Type:

Expression profiling by array

Platforms:

GPL227 GPL228

26 Samples

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(Submitter supplied) Drosophila simulans blue gut larvae vs. white prepupae Keywords: repeat sample

Organism:

Drosophila simulans; Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL228

4 Samples

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(Submitter supplied) Drosophila melanogaster Samarkand blue gut larvae vs. white prepupae Keywords: repeat sample

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL228

6 Samples

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(Submitter supplied) Drosophila melanogaster OregonR blue gut larvae vs. white prepupae Keywords: repeat sample

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL228

4 Samples

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(Submitter supplied) Drosophila melanogaster Netherlands2 blue gut larvae vs. white prepupae Keywords: repeat sample

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL228

4 Samples

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