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Links from GEO DataSets

Items: 13

1.

B bifidum actively changes the gene expression profile induced by L acidophilus in murine dendritic cells

(Submitter supplied) Dendritic cells (DC) play a pivotal regulatory role in activation of the innate as well as the adaptive part of the immune system by responding to environmental microorganisms. We have previously shown that some lactobacilli strains induce a strong production of the pro-inflammatory and Th1 polarizing cytokine IL-12 in DC. Contrary, bifidobacteria do not induce IL-12, but are able to inhibit the IL-12 production induced by lactobacilli. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS3813
Platform:
GPL1261
12 Samples
Download data: CEL
Series
Accession:
GSE20302
ID:
200020302
2.
Full record GDS3813

Bifidobacterium bifidum and Lactobacillus acidophilus co-stimulation effect on bone-marrow derived dendritic cells

Analysis of dendritic cells (DC) co-stimulated with B. bifidum and L. acidophilus. DCs are involved in the initiation of both innate and adaptive immunity by responding to environmental microorganisms. Results provide insight into the immune response in DCs elicited by this co-stimulation.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 4 agent sets
Platform:
GPL1261
Series:
GSE20302
12 Samples
Download data: CEL
3.

Lactobacillus acidophilus induces virus immune defense genes in murine dendritic cells by a TLR-2 dependent mechanism

(Submitter supplied) Lactobacilli are probiotics that, among other health promoting effects, have been ascribed immunostimulating and virus preventive properties. Certain lactobacilli species have been shown to possess strong IL-12 inducing properties. As IL-12 production depends on the up-regulation of type I interferons, we hypothesized that the strong IL-12 inducing capacity of L. acidophilus NCFM in murine bone marrow derived DC is caused by an up-regulation of IFN-β, which subsequently stimulates the induction of IL-12 and the dsRNA binding toll like receptor (TLR)-3. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
16 Samples
Download data: CEL
Series
Accession:
GSE18460
ID:
200018460
4.

Lactobacillus acidophilus and Helicobacter pylori stimulation of bone marrow derived macrophage

(Submitter supplied) Helicobacter pylori causes chronic gastritis and avoids elimination by the immune system of the infected host. The commensal bacterium Lactobacillus acidophilus has been reported to exert beneficial effects as a supplement during H. pylori eradication therapy. In the present study, we applied whole genome microarray analysis to compare the immune response induced in murine bone marrow derived macrophages (BMDM) stimulated with L. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL4134
12 Samples
Download data: TXT
Series
Accession:
GSE42622
ID:
200042622
5.

Host response to Bifidobacterium bifidum PRL2010 treatment as determined through global transcription profiling

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL17385 GPL17386
12 Samples
Download data: TXT
Series
Accession:
GSE48533
ID:
200048533
6.

Bifidobacterium bifidum PRL2010 actively changes the expression profiles of mouse

(Submitter supplied) We studied the global transcription profiling of mouse upon colonization with Bifidobacterium bifidum PRL2010 by using DNA microarrays.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL17386
4 Samples
Download data: TXT
Series
Accession:
GSE48495
ID:
200048495
7.

Bifidobacterium bifidum PRL2010 actively changes the expression profiles of human cell lines

(Submitter supplied) We studied the global transcription profiling of human cell lines upon colonization with Bifidobacterium bifidum PRL2010 by using DNA microarrays.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL17385
8 Samples
Download data: TXT
Series
Accession:
GSE48494
ID:
200048494
8.

Role of interleukin-4 in the licensing of dendritic cells for the induction of Th2 responses

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by array
Platforms:
GPL10333 GPL4134
6 Samples
Download data: GPR, TXT
Series
Accession:
GSE39863
ID:
200039863
9.

Role of interleukin-4 in the licensing of dendritic cells for the induction of Th2 responses [A]

(Submitter supplied) T helper type 2 (Th2) responses are crucial for defense against infections by helminths and are responsible for the development of allergic reactions that can lead to severe clinical disorders, such as asthma or anaphylaxis, and ultimately to death. The induction of Th2 responses requires a specific activation process, triggered by specialized dendritic cells (DCs), by which naive CD4+ Th0 cells acquire the capacity to produce Th2 cytokines. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL4134
4 Samples
Download data: GPR
Series
Accession:
GSE39862
ID:
200039862
10.

Role of interleukin-4 in the licensing of dendritic cells for the induction of Th2 responses [B]

(Submitter supplied) T helper type 2 (Th2) responses are crucial for defense against infections by helminths and are responsible for the development of allergic reactions that can lead to severe clinical disorders, such as asthma or anaphylaxis, and ultimately to death. The induction of Th2 responses requires a specific activation process, triggered by specialized dendritic cells (DCs), by which naive CD4+ Th0 cells acquire the capacity to produce Th2 cytokines. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL10333
2 Samples
Download data: TXT
Series
Accession:
GSE39858
ID:
200039858
11.

Expression data from IL-1β-stimulated immature human enterocytes treated with probiotic-conditioned media

(Submitter supplied) The conditioned media from Bifidobacterium infantis (BCM) and Lactobacillus acidophilus (LCM) were reported to promote maturation of innate immune response gene expression, which explained the protective effects of probiotics in clinical necrotizing enterocolitis. We used microarray analysis to investigate the expression of genes involved in regulation of BCM and LCM in IL-1β stimulated immature human enterocytes. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL16686
17 Samples
Download data: CEL
Series
Accession:
GSE62208
ID:
200062208
12.

Acid sensitivity and opp transport regulation in L. acidophilus

(Submitter supplied) A whole-genome microarray containing 97.4 % of the annotated genes of L. acidophilus was employed to compare genome-wide patterns of transcription at varying pHs between the wild type parent and a histidine protein kinase mutant Keywords: ordered
Organism:
Lactobacillus acidophilus
Type:
Expression profiling by array
Platform:
GPL1401
6 Samples
Download data
Series
Accession:
GSE1976
ID:
200001976
13.

Identification of reference genes for quantitative Real-Time PCR in Bifidobacterium bifidum PRL2010 based on transcriptome analysis

(Submitter supplied) In this study, we investigated the transcriptome of Bifidobacterium bifidum PRL2010 during in vitro growth by micro array technology. When B. bifidum PRL2010 was grown in liquid broth, 425 of the 1644 PRL2010 genes represented on the array were expressed in at least one of the three investigated growth phases, i.e., lag-, exponential and stationary phase. These transcriptional analyses identified a core in vitro transcriptome encompassing 150 genes, which resulted expressed in all phases. more...
Organism:
Bifidobacterium bifidum; Bifidobacterium bifidum PRL2010
Type:
Expression profiling by array
Platform:
GPL13951
4 Samples
Download data: TXT
Series
Accession:
GSE30832
ID:
200030832
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