Similar studies for GEO DataSets (Select 200022293) - GEO DataSets

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Items: 2

Select item 2000222931.

Engineering endochondral ossification using Sonic Hedgehog for bone regeneration

(Submitter supplied) Endochondral ossification (EO) is the natural route for the regeneration of large and mechanically challenged bone defects. Regeneration occurs via a fibrocartilagenous phase which turns into bone upon vascularization and the formation of a transient collagen type X extra cellular matrix. These two critical initiator of EO are mediated by Hedgehog proteins. We investigated a tissue engineering approach using Sonic Hedgehog (Shh) as a pleiotropic factor regulating the in vitro formation of a vascularized bone tissue precursor for in vivo endochondral bone formation. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4482
Platform:: GPL10526
6 Samples

Download data: CEL

Series

Accession:: GSE22293

ID:: 200022293

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 44822.

Sonic Hedgehog inhibitor cyclopamine effect on co-culture of mesenchymal stem cells and umbilical vein endothelial cells

Analysis of a co-culture of 92% human mesenchymal stem cells (hMSC) and 8% human umbilical vein endothelial cells (huvEC) treated with the Sonic Hedgehog morphogen inhibitor cyclopamine. The co-culture of hMSC and huvEC supports the formation of a primitive three dimensional vascular network.