Similar studies for GEO DataSets (Select 200022902) - GEO DataSets

Select item 2000229021.

Identification of a Novel Bacteriocin Regulatory System in Streptococcus mutans

(Submitter supplied) Recently, we described the function of a novel two-gene regulatory system consisting of a LytTR family transcription regulator and a membrane protein, which we referred to as the hdrRM operon. We determined that the HdrRM system controls the expression of another similar regulatory system annotated as SMU.2080 and SMU.2081. Like hdrRM, the SMU.2080 – 2081 operon encodes a LytTR family transcription regulator and membrane protein, which we now refer to as BrsR and BrsM, respectively. more...

Organism:: Streptococcus mutans

Type:: Expression profiling by array

Platform:: GPL4769
2 Samples

Download data: CEL

Series

Accession:: GSE22902

ID:: 200022902

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001102752.

Characterization of the trehalose utilization operon in Streptococcus mutans reveals that the TreR transcriptional regulator is involved in stress response pathways and toxin production

(Submitter supplied) Streptococcus mutans, the organism most frequently associated with the development of dental caries, is able to utilize a diverse array of carbohydrates for energy metabolism. One such molecule is trehalose, a disaccharide common in human foods, which has recently been implicated in enhancing the virulence of epidemic strains of the pathogen, Clostridium difficile. In this study, deletion mutants of all three genes in the putative S. more...

Organism:: Streptococcus mutans

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24591
18 Samples

Download data: TXT, XLSX

Series

Accession:: GSE110275

ID:: 200110275

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001484013.

A dedicated three component regulatory system (GSP/Ghk/Grr) activates gallocin transcription in Streptococcus gallolyticus UCN34

(Submitter supplied) Bacteriocins are natural antimicrobial peptides produced by a bacterium to kill closely related competitors. Streptococcus gallolyticus subsp. gallolyticus (Sgg) UCN34 produces a two-component bacteriocin named gallocin to colonize the gut by killing resident enterococci. In the present work, we investigated how gallocin was regulated by deleting individually three genes present in the locus and encoding potentially an inducing peptide (gsp), a histidine kinase (ghk) and a LytTR-containing response regulator (grr). more...

Organism:: Streptococcus gallolyticus UCN34

Type:: Expression profiling by high throughput sequencing

Platform:: GPL28370
12 Samples

Download data: TXT

Series

Accession:: GSE148401

ID:: 200148401

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000659824.

Transcriptional response of Streptococcus mutans in chemically defined medium (CDM) towards the autoinducers CSP and XIP

(Submitter supplied) S. mutans UA159 was cultivated in chemically defined medium. Changes in the transcriptome in response to the autoinducing peptides CSP and XIP were monitored for 30 minutes.

Organism:: Streptococcus mutans UA159

Type:: Expression profiling by high throughput sequencing

Platform:: GPL19789
20 Samples

Download data: TXT

Series

Accession:: GSE65982

ID:: 200065982

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000183555.

Gene expression of Streptococcus mutans pknB mutant versus wild type strain

(Submitter supplied) Bacteria can detect, transmit and react to signals from the outside world by using two-component systems an serine-threonine kinases and phosphatases. Streptococcus mutans contains one serine-threonine kinase, encoded by pknB. A gene encoding a serine-threonine phosphatase, pppL, is located downstream of pknB. In this study, the phenotypes of single mutants in pknB and pppL and a pknBpppL double mutant were characterized. more...

Organism:: Streptococcus mutans UA159

Type:: Expression profiling by array

Platform:: GPL9332
3 Samples

Download data: TXT

Series

Accession:: GSE18355

ID:: 200018355

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Select item 2000632136.

Regulation of PTSBio by transcriptional repressor NigR

(Submitter supplied) In this study we analyzed the transcriptional regulation of the operon (OBio) encoding the PTSBio and showed that it was repressed by NigR, a LacI-like transcriptional regulator. To elucidate the role of NigR in regulation of S. mutans carbohydrate transporters we performed full genome expression microarrays using custom Affymetrix chip. Expression microarray analysis was performed with ΔnigR grown in CDM supplemented with glucose and compared to that of WT grown under identical conditions. more...

Organism:: Streptococcus mutans UA159; Streptococcus mutans

Type:: Expression profiling by array

Platform:: GPL4769
4 Samples

Download data: CEL, CHP

Series

Accession:: GSE63213

ID:: 200063213

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000220197.

Peptide alarmone signalling triggers an auto-active bacteriocin necessary for genetic competence

(Submitter supplied) The induction of genetic competence is a strategy used by bacteria to increase their genetic repertoire under stressful environmental conditions. Recently, Streptococcus pneumoniae has been shown to co-ordinate the uptake of transforming DNA with fratricide via increased expression of the peptide pheromone responsible for competence induction. Here, we document that environmental stress-induced expression of the peptide pheromone competence-stimulating peptide (CSP) in the oral pathogen Streptococcus mutans. more...