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Links from GEO DataSets

Items: 6

1.

Reconstituted human epidermis cultures treated with IL-1 family cytokines for 24 hours.

(Submitter supplied) Analysis of stratified epidermal cultures treated with IL-1a, IL-1F5, IL-1F6, IL-1F8 and IL-1F9 to determine the effects of these cytokines at 24h. Results provide insight into the role of IL-1 family cytokines in the pathogenesis of psoriasis.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6244
16 Samples
Download data: CEL
Series
Accession:
GSE25400
ID:
200025400
2.

Cytokine treated normal human epidermal keratinocytes

(Submitter supplied) Normal human epidermal keratinocytes (NHEK) from neonatal foreskin were cultured in serum-free EpiLife medium with human KC growth supplement (0.2% bovine pituitary extract (v/v), 5ug bovine insulin, 5ug/ml bovine transferrin, 0.5ng/ml human EGF, and 0.18 ug/ml hydrocortisone) from Cascade Biologics. Cultures were treated with recombinant cytokines from R&D Systems. J Immunol. 2007 Feb 15;178(4):2229-40. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS2611
Platform:
GPL570
25 Samples
Download data: CEL, EXP
Series
Accession:
GSE7216
ID:
200007216
3.
Full record GDS2611

Interleukin-20 subfamily cytokines effect on epidermal keratinocytes

Analysis of cultured epidermal keratinocytes treated with various cytokines of the interleukin-20 (IL-20) subfamily. IL-20 cytokines are up-regulated in psoriatic skin. Results provide insight into the role of IL-20 cytokines in the pathogenesis of psoriasis.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 9 agent, 2 other sets
Platform:
GPL570
Series:
GSE7216
25 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS2611
ID:
2611
4.

Human cathelicidin antimicrobial peptide LL37 effect on human neonatal epidermal keratinocytes (NHEKs).

(Submitter supplied) Analysis of undifferentiated keratinocytes or differentiated keratinocytes stimulated with or without human cathelicidin antimicrobial peptide (CAMP) LL37. Results provide insight into the biological effects of CAMP on human keratinocytes.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6480
12 Samples
Download data: TXT
Series
Accession:
GSE49472
ID:
200049472
5.

IL-36 and IL-17A Cooperatively Induce a Psoriasis-like Gene Expression Response in Human Keratinocytes

(Submitter supplied) In this study we tested interactions between IL-36 and IL-17A in human keratinocytes. 24 hours of IL-36 stimulation in keratinocytes promoted IL-36, IL-17C, and characteristic psoriasis-related molecule expressions in normal human epidermal keratinocytes in dose-dependent manners as measured by mRNA and protein quantification.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
12 Samples
Download data: CEL
Series
Accession:
GSE160904
ID:
200160904
6.

Neutrophils drive skin autoinflammation by releasing IL-26

(Submitter supplied) we profiled the inflammatory transcriptome of skin lesions from pustular psoriasis patients
Organism:
Homo sapiens
Type:
Other
Platform:
GPL31171
95 Samples
Download data: RCC
Series
Accession:
GSE255248
ID:
200255248
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