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Links from GEO DataSets

Items: 9

1.

WT vs KO mecA comparison

(Submitter supplied) Transcriptional profiling of S. thermophilus LMD-9 wild-type compared to the isogenic mutant strain CB052 (deletion of mecA, STER_0216) for the identification of the MecA regulon. Cells were grown in THB medium supplemented with glucose 1% (THBG) and sampled at OD600 = 0.4 for mRNA extraction
Organism:
Streptococcus thermophilus; Streptococcus thermophilus LMD-9
Type:
Expression profiling by array
Platform:
GPL13365
3 Samples
Download data: TXT
Series
Accession:
GSE28371
ID:
200028371
2.

WT vs KO comX comparison

(Submitter supplied) Transcriptional profiling of S. thermophilus LMD-9 wild-type compared to the isogenic mutant strain CB003 (deletion of comX, STER_0189) for the identification of the ComX regulon. Cells were grown in CDM medium supplemented with lactose 1% (CDML) and sampled at OD600 = 0.4 for mRNA extraction
Organism:
Streptococcus thermophilus LMD-9; Streptococcus thermophilus
Type:
Expression profiling by array
Platform:
GPL13365
3 Samples
Download data: TXT
Series
Accession:
GSE28372
ID:
200028372
3.

Inhibition of an Rgg-like Regulator in Streptococcus mutans by the Novel Peptide XrpA

(Submitter supplied) BACKGROUND: Streptococcus mutans, the etiological agent of human dental caries, displays complex regulation of natural genetic competence. Competence development in S. mutans is controlled by a peptide derived from ComS (comX inducing peptide, XIP); which along with the cytosolic regulator ComR controls the expression of the alternative sigma factor comX, the master regulator of competence development. more...
Organism:
Streptococcus mutans
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21130
9 Samples
Download data: TXT
Series
Accession:
GSE110167
ID:
200110167
4.

WT vs WTmitomycinC comparison

(Submitter supplied) Transcriptional profiling of S. thermophilus LMD-9 wild-type in the presence of mitomycin C. Cells were grown in CDM medium supplemented with lactose 1% (CDML), without or with mitomycin C 0.08 microg/ml, and sampled at OD600 = 0.4 for mRNA extraction.
Organism:
Streptococcus thermophilus; Streptococcus thermophilus LMD-9
Type:
Expression profiling by array
Platform:
GPL13365
3 Samples
Download data: TXT
Series
Accession:
GSE35518
ID:
200035518
5.

WT vs KO hdiR comparison

(Submitter supplied) Transcriptional profiling of S. thermophilus LMD-9 wild-type compared to the isogenic mutant strain CB0082 (deletion of hdiR, STER_0918) for the identification of the HdiR regulon. Cells were grown in CDM medium supplemented with lactose 1% (CDML) and sampled at OD600 = 0.4 for mRNA extraction
Organism:
Streptococcus thermophilus LMD-9; Streptococcus thermophilus
Type:
Expression profiling by array
Platform:
GPL13365
3 Samples
Download data: TXT
Series
Accession:
GSE35517
ID:
200035517
6.

Transcriptomic analysis of Lactococcus lactis ssp. cremoris KW2 after ComX constitutive production

(Submitter supplied) Lactococcus lactis is one of the most important lactic acid bacterium used in the dairy industry. Activation of natural DNA transformation in this species would greatly improve the selection of novel strains with desired industrial traits. Here, we investigate the activation of natural transformation in L. lactis ssp. cremoris KW2, a strain of plant origin whose genome encodes the master competence regulator ComX and the complete set of essential late gene products required for natural transformation under its potential control. more...
Organism:
Lactococcus cremoris
Type:
Expression profiling by high throughput sequencing
Platform:
GPL22400
2 Samples
Download data: XLSX
Series
Accession:
GSE86476
ID:
200086476
7.

The dynamic transcriptome of natural competence in Streptococcus suis

(Submitter supplied) Streptococcus suis is a major pig pathogen as well as an emerging zoonotic pathogen. In a previous study (Zaccaria et al. Plos One DOI: 10.1371/journal.pone.0099394) we identified the natural pheromone-induced competence system of S. suis. To identify the mechanisms enabling competence, gene expression analysis of bacteria induced or not for competence, and in presence or absence of exogenous DNA, was assessed at 5, 15 and 45 minutes after pheromone addition. more...
Organism:
Streptococcus suis
Type:
Expression profiling by array
Platform:
GPL16024
16 Samples
Download data: TXT, XLSX
Series
Accession:
GSE74507
ID:
200074507
8.

Subpopulation-specific transcriptome analysis of cytometrically sorted Streptococcus mutans cells: Analysis of CSP-mediated intrapopulation diversity

(Submitter supplied) Transcriptional profiling of the competence-stimulating peptide (CSP) response in Streptococcus mutans of FACS-separated subpopulations and mixed cells of a clonal culture. CSP-mediated competence development in S. mutans is a transient and biphasic process since only a subpopulation induces expression of ComX in the presence of CSP and activation of the DNA uptake machinery in this fraction shuts down ~3-4 hours post induction. more...
Organism:
Streptococcus mutans UA159; Streptococcus mutans
Type:
Expression profiling by array
Platform:
GPL10540
6 Samples
Download data: TXT
Series
Accession:
GSE25284
ID:
200025284
9.

The CovR environmental sensor orchestrates competence bimodality in salivarius streptococci 

(Submitter supplied) In bacteria, phenotypic heterogeneity rescues the need for diversity in isogenic populations and allow concomitant multiple survival strategies when choosing only one is too risky. This powerful tactic is exploited for competence in streptococci and results in a bimodal activation, where only a subset of the community triggers the system. Deciphering the mechanisms underlying this puzzling behavior has remained challenging, especially since its study has been mainly achieved in S. more...
Organism:
Streptococcus salivarius
Type:
Expression profiling by high throughput sequencing
Platform:
GPL23620
3 Samples
Download data: XLSX
Series
Accession:
GSE158512
ID:
200158512
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Supplemental Content

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