GEO DataSets

(Submitter supplied) Investigate the persistent effects of early postnatal overnutrition on the developmental establishment of the DNA methylation in the mouse hypothalamus.

Organism:

Mus musculus

Type:

Methylation profiling by genome tiling array

Platform:

GPL14637

2 Samples

Download data: TXT

(Submitter supplied) Gene expression microarray profiling in adult (P180) small litter vs control mice.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL6887

12 Samples

Download data: TXT

(Submitter supplied) Investigate the genome-wide DNA methylation changes in the mouse hypothalamus during the suckling period.

Organism:

Mus musculus

Type:

Methylation profiling by genome tiling array

Platform:

GPL14637

2 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus

Type:

Methylation profiling by high throughput sequencing; Expression profiling by array

Platforms:

GPL13112 GPL17331

22 Samples

Download data: TXT

(Submitter supplied) Human epidemiologic and animal model data indicate that early environmental influences can persistently alter an individual’s risk of obesity. Environmental effects on hypothalamic developmental epigenetics provide a strong candidate mechanism to explain such ‘developmental programming’ of obesity. To advance our understanding of these processes, it is essential to determine to what extent the diversity of hypothalamic cell types is regulated by epigenetic differences, and when these are established. more...

Organism:

Mus musculus

Type:

Methylation profiling by high throughput sequencing

Platform:

GPL13112

20 Samples

Download data: TXT

(Submitter supplied) The goal is to compare the DNA methylation patterns between ARH and PVH to examine to what extent DNA methylation is region specific in genome scale.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL17331

2 Samples

Download data: TXT

(Submitter supplied) Hypothalami from Fat (FL) and Lean lines (LL) of juvenile broiler chickens were obtained by divergent selection for high or low levels of abdominal fat at SRA-INRA, France. Gene expression patterns were measured during the development of adiposity at 1 to 7 weeks of age. Differentially expressed genes associated with line, age, or line-by-age were identified. Various phenotypic and metabolic alterations are present between the lines (i.e., abdominal fat, T3 levels and glycemia), however there are no alterations in ad libitum food intake between the lines. more...

Organism:

Gallus gallus

Type:

Expression profiling by array

Platform:

GPL1731

8 Samples

Download data: TXT