GEO DataSets

(Submitter supplied) Background: The Anopheles gambiae salivary glands play a major role in malaria transmission and express a variety of bioactive components that facilitate blood-feeding by preventing platelet aggregation, blood clotting, vasodilatation, and inflammatory and other reactions at the probing site on the vertebrate host. Results: We have performed a global transcriptome analysis of the A. gambiae salivary gland response to blood-feeding, to identify candidate genes that are involved in hematophagy. more...

Organism:

Anopheles gambiae

Type:

Expression profiling by array

Platform:

GPL10753

3 Samples

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(Submitter supplied) In spite of the many recent developments in the field of vector sialomics, the salivary glands of larvalmosquitoes have been largely unexplored. We used whole-transcriptome microarray analysis to create a gene-expression profile of the salivary gland tissue of fourth-instar Anopheles gambiae larvae, and compare it to the gene-expression profile of a matching group of whole larvae. We identified a total of 221 probes with expression values that were (a) significantly enriched in the salivary glands, and (b)sufficiently annotated as to allow the prediction of the presence/absence of signal peptides in their corresponding gene products. more...

Organism:

Plasmodium falciparum; Anopheles gambiae

Type:

Expression profiling by array

Platform:

GPL1321

6 Samples

Download data: CEL

(Submitter supplied) Anopheles gambiae, the primary African malarial mosquito, exhibits numerous behaviors that are under diel and circadian control, including locomotor activity, swarming, mating, host seeking, eclosion, egg laying and sugar feeding. However, little has been performed to elucidate the molecular basis for these daily rhythms. To study how gene expression is globally regulated by diel and circadian mechanisms, we have undertaken a DNA microarray analysis of A. more...

Organism:

Plasmodium falciparum; Anopheles gambiae

Type:

Expression profiling by array

Dataset:

GDS4261

Platform:

GPL1321

104 Samples

Download data: CEL

Analysis of heads and bodies of mated, non-blood-fed, adult females maintained under a 12hr:12hr light:dark (LD) cycle or constant dark (DD) conditions; samples were collected every 4hr for 48 hr. Results provide insight into molecular mechanisms under circadian and LD cycle control.

Organism:

Plasmodium falciparum; Anopheles gambiae

Type:

Expression profiling by array, transformed count, 2 growth protocol, 26 time, 2 tissue sets

Platform:

GPL1321

Series:

GSE22585

104 Samples

Download data: CEL

(Submitter supplied) Anopheles gambiae mosquitoes play an important role in malaria transmission. In sub-Saharan Africa, the dry season can last several months. The mechanisms for mosquito population to survive through the dry season are poorly understood. One possible mechanism is that adults increase their desiccation tolerance over the dry season. Genetic analyses have shown that inversions 2La, 2Rb, 2Rc, 2Rd and 2Ru are associated with aridity resistance, however little is known about the transcriptional response of genes in response to desiccation. more...

Organism:

Plasmodium falciparum; Anopheles gambiae

Type:

Expression profiling by array

Dataset:

GDS4552

Platform:

GPL1321

19 Samples

Download data: CEL

Analysis of adult females exposed to 30% (desiccated) relative humidity for up to 36 hrs. The An. gambiae malaria vector populations are observed year round but their densities are low during the dry season. Results provide insight into molecular basis of the malaria vector's desiccation response.

Organism:

Plasmodium falciparum; Anopheles gambiae

Type:

Expression profiling by array, count, 3 stress, 3 time sets

Platform:

GPL1321

Series:

GSE25433

19 Samples

Download data: CEL

(Submitter supplied) The female midgut compartment specifc transcriptomes have been determined with microarray analyses. Keywords: glass slide microarray analyses

Organism:

Anopheles gambiae

Type:

Expression profiling by array

Platform:

GPL4579

18 Samples

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(Submitter supplied) Background: The mosquito Anopheles gambiae is a major vector of human malaria. Increasing evidence indicates that blood cells (hemocytes) comprise an essential arm of the mosquito innate immune response against both bacteria and malaria parasites. To further characterize the role of hemocytes in mosquito immunity, we undertook the first genome-wide transcriptomic analyses of adult female An. gambiae hemocytes following infection by two species of bacteria and a malaria parasite. more...

Organism:

Anopheles gambiae

Type:

Expression profiling by array

Platforms:

GPL8551 GPL8550 GPL8552

11 Samples

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(Submitter supplied) We report on the transcriptome differences in the salivary glands of cabbage looper larvae fed on different diets

Organism:

Trichoplusia ni

Type:

Expression profiling by high throughput sequencing

Platform:

GPL23793

9 Samples

Download data: TXT

(Submitter supplied) Numerous studies have examined changes in transcript levels after Anopheles gambiae takes a blood meal. Marinotti et al. (2006) used microarrays and reported massive changes in transcript levels 3 h after feeding (BF3h) compared to non-blood fed (NBF). We were intrigued by the number of transcripts for structural cuticular proteins (CPs) that showed such major differences in levels and employed paired-end (50 bp) RNA-seq technology to compare whole body transcriptomes from 5-day-old females NBF and BF3h. more...

Organism:

Anopheles gambiae

Type:

Expression profiling by high throughput sequencing

Platform:

GPL17644

8 Samples

Download data: GTF

(Submitter supplied) During blood feeding haematophagous arthropods inject into their hosts a cocktail of salivary proteins whose main role is to counteract host haemostasis, inflammation and immunity. However, animal body fluids are known to also carry miRNAs. To get insights into saliva and salivary gland miRNA repertoires of the African malaria vector Anopheles coluzzii we used small RNA-Seq and identified 214 miRNAs, including tissue-enriched, sex-biased and putative novel anopheline miRNAs. more...

Organism:

Anopheles coluzzii

Type:

Non-coding RNA profiling by high throughput sequencing

Platforms:

GPL18984 GPL25627

14 Samples

Download data: TXT