GEO DataSets

(Submitter supplied) Transcriptional profiling of S. thermophilus LMD-9 wild-type in the presence of mitomycin C. Cells were grown in CDM medium supplemented with lactose 1% (CDML), without or with mitomycin C 0.08 microg/ml, and sampled at OD600 = 0.4 for mRNA extraction.

Organism:

Streptococcus thermophilus; Streptococcus thermophilus LMD-9

Type:

Expression profiling by array

Platform:

GPL13365

3 Samples

Download data: TXT

(Submitter supplied) Transcriptional profiling of S. thermophilus LMD-9 wild-type compared to the isogenic mutant strain CB0082 (deletion of hdiR, STER_0918) for the identification of the HdiR regulon. Cells were grown in CDM medium supplemented with lactose 1% (CDML) and sampled at OD600 = 0.4 for mRNA extraction

Organism:

Streptococcus thermophilus LMD-9; Streptococcus thermophilus

Type:

Expression profiling by array

Platform:

GPL13365

3 Samples

Download data: TXT

(Submitter supplied) Transcriptional profiling of S. thermophilus LMD-9 wild-type compared to the isogenic mutant strain CB003 (deletion of comX, STER_0189) for the identification of the ComX regulon. Cells were grown in CDM medium supplemented with lactose 1% (CDML) and sampled at OD600 = 0.4 for mRNA extraction

Organism:

Streptococcus thermophilus LMD-9; Streptococcus thermophilus

Type:

Expression profiling by array

Platform:

GPL13365

3 Samples

Download data: TXT

(Submitter supplied) Transcriptional profiling of S. thermophilus LMD-9 wild-type compared to the isogenic mutant strain CB052 (deletion of mecA, STER_0216) for the identification of the MecA regulon. Cells were grown in THB medium supplemented with glucose 1% (THBG) and sampled at OD600 = 0.4 for mRNA extraction

Organism:

Streptococcus thermophilus; Streptococcus thermophilus LMD-9

Type:

Expression profiling by array

Platform:

GPL13365

3 Samples

Download data: TXT

(Submitter supplied) Streptococcus pneumoniae is an opportunistic human pathogen that typically colonizes the nasopharyngeal passage and causes lethal disease in other host niches such as the lung or the meninges. How pneumococcal genes are expressed and regulated at the different stages of its life cycle, as commensal or as pathogen, has not been entirely described. To chart the transcriptional responses of S. pneumoniae, we quantified the transcriptome under 22 different infection-relevant conditions. more...

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by high throughput sequencing

Platform:

GPL24384

34 Samples

Download data: TXT

(Submitter supplied) The SOS response is a conserved pathway that is activated under certain stress conditions and is regulated by the repressor LexA and the activator RecA. The food-borne pathogen Listeria monocytogenes contains RecA and LexA homologs, but their roles in Listeria have not been established. In this study, we identified the SOS regulon in L. monocytogenes by comparing the transcription profiles of the wild-type strain and the ΔrecA mutant strain after exposure to the DNA damaging agent mitomycinC (MMC). more...

Organism:

Listeria monocytogenes EGD-e

Type:

Expression profiling by array

Platform:

GPL7235

16 Samples

Download data: TXT

(Submitter supplied) RNA-sequencing of two Salmonella enterica strains (WT, ∆yebEFG) in standard laboratory conditions (LB to ESP), and in SOS-response inducing conditions (LB+nalidixic acid)

Organism:

Salmonella enterica

Type:

Expression profiling by high throughput sequencing

Platform:

GPL27048

12 Samples

Download data: TXT

(Submitter supplied) Streptococcus suis is a major pig pathogen as well as an emerging zoonotic pathogen. In a previous study (Zaccaria et al. Plos One DOI: 10.1371/journal.pone.0099394) we identified the natural pheromone-induced competence system of S. suis. To identify the mechanisms enabling competence, gene expression analysis of bacteria induced or not for competence, and in presence or absence of exogenous DNA, was assessed at 5, 15 and 45 minutes after pheromone addition. more...

Organism:

Streptococcus suis

Type:

Expression profiling by array

Platform:

GPL16024

16 Samples

Download data: TXT, XLSX

(Submitter supplied) In bacteria, phenotypic heterogeneity rescues the need for diversity in isogenic populations and allow concomitant multiple survival strategies when choosing only one is too risky. This powerful tactic is exploited for competence in streptococci and results in a bimodal activation, where only a subset of the community triggers the system. Deciphering the mechanisms underlying this puzzling behavior has remained challenging, especially since its study has been mainly achieved in S. more...

Organism:

Streptococcus salivarius

Type:

Expression profiling by high throughput sequencing

Platform:

GPL23620

3 Samples

Download data: XLSX

(Submitter supplied) Staphylococcus aureus is a leading cause of human disease and can be difficult to treat due to both multi-drug resistance and the organism’s remarkable ability to persist in the host, which is thought to result from several complex regulatory networks that modify transcription in response to environmental stress. In this study, we characterize the global transcriptional response of S. aureus strain 8325 to the antibiotic ciprofloxacin. more...

Organism:

Staphylococcus aureus

Type:

Expression profiling by array

Platform:

GPL4324

13 Samples

Download data: MEV

(Submitter supplied) Whole genome expression profile comparing MGAS315 treated with XIP pheromone versus vehicle-treated cells Interpretations are described further in the manuscript to be submitted: authors Mashburn-Warren, Morrison, and Federle. Title: The Cryptic Competence Pathway in Streptococcus pyogenes is Controlled by a Peptide Pheromone.

Organism:

Streptococcus pyogenes MGAS315; Streptococcus pyogenes NZ131

Type:

Expression profiling by genome tiling array

Platform:

GPL15576

2 Samples

Download data: CALLS, PAIR, TXT

(Submitter supplied) We show that treatment with HPUra (for S. pneumoniae) and trimethoprim (for E. coli) leads to a skewed gene dosage profile (increase around the origin of replication), which is also propagated to the transcriptome level. Kanamycin, however, does not have this effect. In case of S. pneumoniae this shift in gene dosage distribution leads to the population-wide activation of competence.

Organism:

Streptococcus pneumoniae; Escherichia coli

Type:

Genome variation profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platforms:

GPL14548 GPL18183

18 Samples

Download data: TXT

(Submitter supplied) The aim of this study is to identify the response of S. pneumoniae to HPUra-induced replication stress on transcriptional level in a wild type strain.

Organism:

Streptococcus pneumoniae D39

Type:

Expression profiling by array

Platform:

GPL11484

12 Samples

Download data: TXT

(Submitter supplied) We have looked at the transcriptional response of well characterised Synechococcus open ocean (WH8102) and coastal (CC9311) isolates to two DNA damaging agents, mitomycin C and ethidium bromide, using whole genome expression microarrays. The coastal strain, which was able to grow on higher concentrations of both chemicals, showed differential regulation of a larger proportion of its genome following ‘toxic shock’ treatment with each agent. more...

Organism:

Parasynechococcus marenigrum WH 8102; Synechococcus sp. CC9311

Type:

Expression profiling by array

Platforms:

GPL15878 GPL15879

24 Samples

Download data: MEV, TAV