Similar studies for GEO DataSets (Select 200048912) - GEO DataSets

Select item 2000489121.

In vitro selection for chitosan-resistant Staphylococcus aureus - phenotypic and molecular characterisation of resistance development

(Submitter supplied) A mutant of SG511 (wild type isolate), resistant to the presence of chitosan (polycationic molecule) was obtained following serial passage experiments resistance to chitosan exposition. Transcriptomic experiments showed alteration in the expression of genes involved in the cell wall regulon resulting in the modification of susceptibility phenotype against cell wall active antibiotics

Organism:: Staphylococcus aureus; Staphylococcus aureus subsp. aureus Mu50; Staphylococcus aureus subsp. aureus MRSA252; Staphylococcus aureus subsp. aureus MSSA476; Staphylococcus aureus subsp. aureus USA300; Staphylococcus aureus subsp. aureus MW2; Staphylococcus aureus subsp. aureus NCTC 8325; Staphylococcus aureus subsp. aureus COL; Staphylococcus aureus subsp. aureus N315

Type:: Expression profiling by array

Platform:: GPL7137
3 Samples

Download data: TXT

Series

Accession:: GSE48912

ID:: 200048912

Select item 2000120162.

Comparative transcriptome analysis of two S. aureus strains with different susceptibilities to mersacidin.

(Submitter supplied) The lantibiotic mersacidin is an antimicrobial peptide of 20 amino acids that is produced by Bacillus sp. strain HIL Y-85,54728. Lantibiotics are antibiotics containing nonproteinogenic amino acids like lanthionine and/or 3-methyllanthionine. Mersacidin interferes with cell wall biosynthesis by targeting the peptidoglycan precursor lipid II and inhibits the growth of MRSA and other gram-positive bacteria. more...

Organism:: Staphylococcus aureus subsp. aureus N315; Staphylococcus aureus

Type:: Expression profiling by array

Platform:: GPL5421
2 Samples

Download data: GPR

Series

Accession:: GSE12016

ID:: 200012016

Select item 2000508423.

In vitro transcriptomic comparison of daptomycin-resistant Staphylococcus aureus

(Submitter supplied) Mutants from SG511 and NCTC8325 (wild type isolates) resistant to daptomycin were obtained following serial passage experiments in vitro. Transcriptomic experiments showed alteration in the expression of genes involved in various pathways including general metabolism, cell wall regulon and lipid metabolism.

Organism:: Staphylococcus aureus; Staphylococcus aureus subsp. aureus Mu50; Staphylococcus aureus subsp. aureus N315; Staphylococcus aureus subsp. aureus MRSA252; Staphylococcus aureus subsp. aureus MSSA476; Staphylococcus aureus subsp. aureus USA300; Staphylococcus aureus subsp. aureus NCTC 8325; Staphylococcus aureus subsp. aureus COL; Staphylococcus aureus subsp. aureus MW2

Type:: Expression profiling by array

Platform:: GPL7137
4 Samples

Download data: TXT

Series

Accession:: GSE50842

ID:: 200050842

Select item 2000468874.

Switching on antibiotic resistance in Staphylococcus aureus – Contribution of WalK and VraS histidine kinases in the development of vancomycin and daptomycin resistance

(Submitter supplied) Staphylococcus aureus is a notorious bacterial pathogen that causes a broad range of human diseases, and isolates that are resistant to several antibiotic classes including last resort antibiotics like vancomycin and daptomycin complicate the situation. We characterized S. aureus VC40, a strain that shows full resistance to vancomycin (MIC of 64 µg/ml) and daptomycin (MIC of 4 µg/ml) as well as a decreased susceptibility to further cell wall active agents. more...

Organism:: Staphylococcus aureus; Staphylococcus aureus subsp. aureus VC40

Type:: Expression profiling by array

Platform:: GPL10537
6 Samples

Download data: TXT

Series

Accession:: GSE46887

ID:: 200046887

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