Similar studies for GEO DataSets (Select 200057715) - GEO DataSets

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Items: 4

Select item 2000577151.

Primary melanoma tumors from CDKN2A mutation carriers do not belong to a distinct molecular subclass.

(Submitter supplied) Analysis of gene expression profiles from sporadic and hereditary primary melanomas. The hypothesis was to test whether any gene expression differences exist between melanomas from CDKN2A mutation carriers and sporadic melanomas.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL16807
297 Samples

Download data: TXT

Series

Accession:: GSE57715

ID:: 200057715

Select item 2000227872.

Affymetrix HG-U133A 2.0 Expression data

(Submitter supplied) Expression .CEL files from Affymetrix HG-U133A 2.0 arrays using DNA from 14 human cell lines derived from metastasized melanoma

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL571
14 Samples

Download data: CEL

Series

Accession:: GSE22787

ID:: 200022787

Select item 2001228353.

Expression data from second oncogene expressing Melanoma Cells.

(Submitter supplied) Among the myriad tumors analyzed to date, cutaneous malignant melanomas bear some of the highest mutational burdens. Thus, it is somewhat surprising that oncogene exclusion between is so pronounced in melanomas where there is only a single melanoma out of 366 sequenced specimens which harbors concurrent BRAF(V600E/M) and NRAS(G13R) mutations (TCGA-ES-A2NC Sample; WWW.bioportal.org), In this senario some NRAS and BRAF mutations co-expressing cells show slow growth phenotypes by under study mechanism. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL16043
12 Samples

Download data: CEL, CHP

Series

Accession:: GSE122835

ID:: 200122835

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001424424.

Integrating Next Generation Sequencing with Morphology Improves Prognostic and Biologic Classification of Spitz Neoplasms [DNA-Seq]

(Submitter supplied) The newest WHO classification suggests eliminating cases with BRAF and NRAS mutations from the categories of Spitz tumors (ST) and Spitz melanoma (SM). We aimed to better characterize the genomics of Spitz neoplasms and assess whether integrating genomic data with morphologic diagnosis improves classification and prognostication. We performed DNA and RNA sequencing on 80 STs, 26 SMs, and 22 melanomas with Spitzoid features (MSF). more...