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Links from GEO DataSets

Items: 7

1.

Next generation sequencing of human immune cell subsets across diseases

(Submitter supplied) This study compared whole transcriptome signatures of 6 immune cell subsets and whole blood from patients with an array of immune-associated diseases. Fresh blood samples were collected from healthy subjects and subjects diagnosed type 1 diabetes, amyotrophic lateral sclerosis, and sepsis, as well as multiple sclerosis patients before and 24 hours after the first treatment with IFN-beta. At the time of blood draw, an aliquot of whole blood was collected into a Tempus tube (Invitrogen), while the remainder of the primary fresh blood sample was processed to highly pure populations of neutrophils, monocytes, B cells, CD4 T cells, CD8 T cells, and natural killer cells. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL15456
134 Samples
Download data: TXT
Series
Accession:
GSE60424
ID:
200060424

PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector

2.

Gene expression profile in MCF7 breast cancer cells after 78 functionallly important molecules were knocked down using siRNA.

(Submitter supplied) Affymetrix microarray data was generated from MCF7 breast cancer cells treated in vitro with siRNAs against 78 transcription factors and signalling molecules.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
89 Samples
Download data: CEL
Series
Accession:
GSE31912
ID:
200031912

PubMed Full text in PMC Similar studies Analyze with GEO2R

3.

Gene expression profile in A375 melanoma cells after 45 functionally important molecules were knocked down using siRNA

(Submitter supplied) Affymetrix microarray data were generated from A375 melanoma cells treated in vitro with siRNAs against 45 transcription factors and signalling molecules.
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4813
Platform:
GPL570
51 Samples
Download data: CEL
Series
Accession:
GSE31534
ID:
200031534

PubMed Full text in PMC Similar studies Analyze with GEO2R

4.
Full record GDS4813

Melanoma cell line response to the depletion of various transcription factors and signaling proteins

Analysis of cultured A375 melanoma cells depleted for various transcription factors and signaling proteins. Results provide insight into the molecular pathogenesis of melanoma.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 47 agent sets
Platform:
GPL570
Series:
GSE31534
51 Samples
Download data: CEL
DataSet
Accession:
GDS4813
ID:
4813

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

5.

Gene Expression Profiling-Based Identification of Molecular Subtypes in Stage IV Melanoma with Different Clinical Outcome

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL6102 GPL6947
79 Samples
Download data
Series
Accession:
GSE22155
ID:
200022155

PubMed Similar studies Analyze with GEO2R

6.

Gene Experssion Profiling-Based Identification of Molecular Subtypes in Stage IV Melanoma with Different Clinical Outcome (validation set)

(Submitter supplied) Purpose: The incidence of malignant melanoma is increasing worldwide in fair-skinned populations. Melanomas respond poorly to systemic therapy, and metastatic melanomas inevitably become fatal. Although spontaneous regression, likely due to immune defense activation, rarely occurs, we lack a biological rationale and predictive markers in selecting patients for immune therapy. Experimental Design: We performed unsupervised hierarchical clustering of global gene expression data from stage IV melanomas in 57 patients. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6947
22 Samples
Download data: TXT
Series
Accession:
GSE22154
ID:
200022154

PubMed Similar studies Analyze with GEO2R

7.

Gene Experssion Profiling-Based Identification of Molecular Subtypes in Stage IV Melanoma with Different Clinical Outcome (test set)

(Submitter supplied) Purpose: The incidence of malignant melanoma is increasing worldwide in fair-skinned populations. Melanomas respond poorly to systemic therapy, and metastatic melanomas inevitably become fatal. Although spontaneous regression, likely due to immune defense activation, rarely occurs, we lack a biological rationale and predictive markers in selecting patients for immune therapy. Experimental Design: We performed unsupervised hierarchical clustering of global gene expression data from stage IV melanomas in 57 patients. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6102
57 Samples
Download data: TXT
Series
Accession:
GSE22153
ID:
200022153

PubMed Similar studies Analyze with GEO2R

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