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Links from GEO DataSets

Items: 6

1.

Gene expression analysis of inguinal white adipose tissue upon cold exposure in ferrets: mainly metabolism is effected

(Submitter supplied) Male ferrets, aged 3 months, were divided into two group: one group remained at 22 degrees Celsius, while the other group was acclimatized to 4 degrees Celsius for one week. After sacrification, inguinal white adipose tissues were dissected, and used for RNA isolation and subsequent global gene expression profiling using custom Agilent ferret-specific 2x400K microarrays. Data analysis indicated that mainly metabolism is significantly upregulated. more...
Organism:
Mustela putorius furo
Type:
Expression profiling by array
Platform:
GPL19292
13 Samples
Download data: TXT
Series
Accession:
GSE62351
ID:
200062351
2.

The cold exposure produce a different gene expression pattern in inguinal and periaortic white adipose

(Submitter supplied) Male ferrets, aged 3 months, were divided into two group: one group remained at 22 degrees Celsius, while the other group was acclimatized to 4 degrees Celsius for one week. After sacrification, inguinal and periaortic white adipose tissues were dissected, and used for RNA isolation and subsequent global gene expression profiling using custom Agilent ferret-specific 2x400K microarrays. Data analysis indicated that while the cold exposure induces an increase on metabolism in inguinal white adopose tissue, in periaortic white adipose tissue this stimulus induces a reduction on expression of genes involved in cell cycle and in immune response.
Organism:
Mustela putorius furo
Type:
Expression profiling by array
Platform:
GPL19292
13 Samples
Download data: TXT
Series
Accession:
GSE62353
ID:
200062353
3.

The Peroxisome Proliferator-Activated Receptor α is dispensable for cold-induced adipose tissue browning in mice

(Submitter supplied) Chronic cold exposure causes white adipose tissue (WAT) to adopt features of brown adipose tissue, a process known as browning. Previous studies have hinted at a possible role for the transcription factor Peroxisome Proliferator-Activated Receptor alpha (PPARα) in cold-induced browning. Here we aimed to investigate the importance of PPARα in driving transcriptional changes during cold-induced browning in mice. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL17400
22 Samples
Download data: CEL
Series
Accession:
GSE110420
ID:
200110420
4.

White adipose tissue browning in the R6/2 mouse model of Huntington's disease

(Submitter supplied) We investigated gene expression signatures in subcutaneous inguinal adipose tissue obtained from wild type and R6/2 mice with the aim to identify gene expression changes and signalling pathway alterations in adipose tissue relevant to HD. Gene expression was assessed using Affymetrix GeneChip® Mouse Gene 2.0 ST Array. Target genes were technically validated using real-time quantitative PCR.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL16570
12 Samples
Download data: CEL, CHP
Series
Accession:
GSE79711
ID:
200079711
5.

Microbiota Depletion Impairs Adaptive Thermogenesis of Both Brown and Beige Adipose Tissue

(Submitter supplied) Comparsion of gene expression in scWAT/pgVAT of Ctrl, ABX and SZ-ABX mice.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21273
26 Samples
Download data: CSV
Series
Accession:
GSE117843
ID:
200117843
6.

Peripheral blood mononuclear cells as a source of cold exposure biomarkers

(Submitter supplied) Male ferrets, aged 3 months, were divided into two group: one group remained at 22 degrees Celsius, while the other group was acclimatized to 4 degrees Celsius for one week. After sacrification, inguinal and periaortic white adipose tissues were dissected, and peripheral blood mononuclear cells (PBMC) were isolated. The three tissues are used for RNA isolation and subsequent global gene expression profiling using custom Agilent ferret-specific 2x400K microarrays. more...
Organism:
Mustela putorius furo
Type:
Expression profiling by array
Platform:
GPL19292
10 Samples
Download data: TXT
Series
Accession:
GSE62352
ID:
200062352
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