GEO DataSets

(Submitter supplied) Japanese quail (Coturnix coturnix japonica) reach sexual maturity early, breed rapidly and successfully, and cost less and require less space than other birds raised for their meat and eggs. Given the value of this species for commercial production and experimental use as well as recent increasing demand, more studies are necessary to determine chromosomal regions and genes associated with gender and breed-differentiation in the species. more...

Organism:

Coturnix japonica

Type:

Expression profiling by high throughput sequencing

Platform:

GPL19652

12 Samples

Download data: CSV

(Submitter supplied) The number of legacy chemicals without toxicity reference values combined with the rate of new chemical development are overwhelming the capacity of the traditional risk assessment paradigm. More efficient approaches are needed to quantitatively estimate chemical risks. In this study, rats were dosed orally with multiple doses of six chemicals for 5 days, 2, 4, and 13 weeks. Target organs were analyzed for traditional histological and organ weight changes and transcriptional changes using microarrays. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL16985

720 Samples

Download data: CEL

(Submitter supplied) Gender differences in brain development and in the prevalence of neuropsychiatric disorders such as depression have been reported. Gender differences in human brain might be related to patterns of gene expression. Microarray technology is one useful method for investigation of gene expression in brain. We investigated gene expression, cell types, and regional expression patterns of differentially expressed sex chromosome genes in brain. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platforms:

GPL91 GPL8300

87 Samples

Download data: CEL

(Submitter supplied) The goal of the sequencing project was to identify differentially expressed genes between four treatments (12 hypothalamus samples from quail per treatment, 6 from each sex).

Organism:

Coturnix japonica

Type:

Expression profiling by high throughput sequencing

Platform:

GPL29437

48 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Coturnix japonica

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL29437 GPL29461

31 Samples

Download data

(Submitter supplied) Chemical risk assessment for avian species typically depends on information from toxicity tests performed in adult birds. Early-life stage (ELS) toxicity tests have been proposed as an attractive alternative, but incorporation of these data into existing frameworks will require knowledge about the similarities/differences between ELS and adult responses. The present study uses transcriptomics to assess hepatic gene expression in ELS and adult Japanese quail following exposure to ethinylestradiol (EE2). more...

Organism:

Coturnix japonica

Type:

Expression profiling by high throughput sequencing

Platform:

GPL29437

15 Samples

Download data: TXT

(Submitter supplied) Chemical risk assessment for avian species typically depends on information from toxicity tests performed in adult birds. Early-life stage (ELS) toxicity tests have been proposed as an attractive alternative, but incorporation of these data into existing frameworks will require knowledge about the similarities/differences between ELS and adult responses. The present study uses transcriptomics to assess hepatic gene expression in ELS and adult Japanese quail following exposure to ethinylestradiol (EE2). more...

Organism:

Coturnix japonica

Type:

Expression profiling by high throughput sequencing

Platform:

GPL29461

16 Samples

Download data: TXT

(Submitter supplied) Artificial selection has resulted in animal breeds with extreme phenotypes. As an organism is made up of many different tissues and organs, each with its own genetic programme, it is pertinent to ask what are the relative contributions of breed or sex when assessed across tissues. Are all tissues equally affected by breed or sex? How relevant is tissue in terms of total transcriptome variability? Keywords: breeds, sex and tissues comparison

Organism:

Sus scrofa

Type:

Expression profiling by array

Platform:

GPL3533

64 Samples

Download data: CEL

(Submitter supplied) Modern 21st century toxicity testing makes use of omics technologies to address critical questions in toxicology and chemical management. Of interest are questions relating to chemical mechanisms of toxicity, differences in species sensitivity, and translation of molecular effects to observable apical endpoints. Our study addressed these questions by comparing apical outcomes and multiple omics responses in early-life stage exposure studies with Japanese quail (JQ; Coturnix japonica) and double crested cormorant (DCCO; Phalacrocorax auritus), representing a model and ecological species, respectively. more...

Organism:

Coturnix japonica; Phalacrocorax auritus

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL30378 GPL29437

29 Samples

Download data: TXT

(Submitter supplied) In the present study, four important somatotropic and reproductive tissues including brain, pituitary, liver, and gonad from 15 females and 15 males were used for transcriptome analysis by RNA-seq. A mean of 37,533,991 high quality clean reads were obtained from each library and 806, 1,482, 818, and 14,695 differentially expressed genes in female and male were identified from brain, pituitary, liver, and gonad, respectively (fold change ≥ 2 and q < 0.05). more...

Organism:

Cynoglossus semilaevis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL24093

24 Samples

Download data: FA, TXT

(Submitter supplied) Background: Transcriptome variability is due to genetic and environmental causes, much like any other complex phenotype. Ascertaining the transcriptome differences between individuals is an important step to understand how selection and genetic drift may affect gene expression. To that end, extant divergent livestock breeds offer an ideal genetic material. Results: We have analyzed with microarrays five tissues from the endocrine axis (hypothalamus, adenohypophysis, thyroid gland, gonads and fat tissue) of 16 pigs from both sexes pertaining to four extreme breeds (Duroc, Large White, Iberian and a cross with SinoEuropean hybrid line). more...

Organism:

Sus scrofa

Type:

Expression profiling by array

Platform:

GPL3533

80 Samples

Download data: CEL

(Submitter supplied) Sexual dimorphism is one of the important topic in mammal species because appearance of males and females is obvious different in all mammal species. In addition to this, molecular mechanisms also very different each other. Furthermore, it is important to employ a variety of tissues in RNA-seq experiment because recent studies imply gene expression pattern are highly tissue specific. Although previous related studies discovered numerous sexually dimorphic mechanism in mammal species, but still, many mechanisms are undiscovered in case of non-model organisms. more...

Organism:

Bos taurus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL15749

40 Samples

Download data: TXT

(Submitter supplied) For many species, parental care critically affects offspring survival. But what drives animals to display parental behaviours towards young? In mammals, pregnancy‐induced physiological transformations seem key in preparing the neural circuits that lead towards attraction (and reduced‐aggression) to young. Beyond mammalian maternal behaviour, knowledge of the neural mechanisms that underlie young‐directed parental care is severely lacking. more...

Organism:

Coturnix japonica

Type:

Expression profiling by high throughput sequencing

Platform:

GPL29461

144 Samples

Download data: TXT

(Submitter supplied) We produced transcriptome data from twenty two blastocysts

Organism:

Bos taurus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL19172

22 Samples

Download data: TXT

(Submitter supplied) Background: The transcriptome of peripheral white blood cells (PWBCs) contains valuable physiological information, thus making them a prime biological sample for investigating mRNA-based biomarkers. However, prolonged storage of whole blood samples can alter gene transcript abundance in PWBCs, compromising the results of biomarker discovery. Here, we designed an experiment to interrogate the impacts of delayed processing of whole blood samples on gene transcript abundance in PWBCs. more...

Organism:

Bos taurus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL26012

30 Samples

Download data: TXT

(Submitter supplied) We used single cell RNAseq to identify the populations and identity of cells present in the japanese quail forebrain during its embryonic stages.

Organism:

Coturnix japonica

Type:

Expression profiling by high throughput sequencing

Platform:

GPL33247

1 Sample

Download data: CSV, MTX, TSV

(Submitter supplied) We have studied different subspecies of the house mouse (M. m. musculus, M. m. domesticus and M. m. castaneus) and their reciprocal F1 hybrids to estimate the within-locus mode of inheritance for subspecies differences in gene expression in three tissues (brain, liver, testis) of male mice. This study investigates mode of inheritance in crosses at a larger taxonomic distance than have been previously systematically investigated. more...

Organism:

Mus musculus domesticus; Mus musculus musculus; Mus musculus castaneus; Mus musculus; Mus musculus musculus x M. m. domesticus; Mus musculus musculus x Mus musculus castaneus

Type:

Expression profiling by array

Platform:

GPL1261

42 Samples

Download data: CEL

(Submitter supplied) The aim of this experiment was to test how female Japanese quail respond to being housed with sick (LPS treated) relative to control males. LPS injected females were also tested.

Organism:

Coturnix japonica

Type:

Expression profiling by high throughput sequencing

Platform:

GPL29461

29 Samples

Download data: TXT