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Links from GEO DataSets

Items: 2

1.

Luteinizing hormone induces ovulation via tumor necrosis factor α-dependent increases in prostaglandin F2α in a nonmammalian vertebrate

(Submitter supplied) Ovulation is induced by the preovulatory surge of luteinizing hormone (LH) that acts on the ovary and triggers the rupture of the preovulatory ovarian follicle by stimulating proteolysis and apoptosis in the follicle wall, causing the release of the mature oocyte. In mammals, the pro-inflammatory cytokine tumor necrosis factor α (TNFα) and prostaglandin F2α (PGF2α) are known to be involved in the control of ovulation but their role mediating the pro-ovulatory actions of LH has not been established. more...
Organism:
Salmo trutta; Oncorhynchus mykiss
Type:
Expression profiling by array
Platform:
GPL16819
8 Samples
Download data: TXT
Series
Accession:
GSE67592
ID:
200067592
2.

Cellular and molecular evidence for a role of tumor necrosis factor alpha in the ovulatory mechanism of trout

(Submitter supplied) The relevance of immune-endocrine interactions to the regulation of ovarian function in teleosts is virtually unexplored. As part of the innate immune response during infection, a number of cytokines such as tumor necrosis factor α (TNFα) and other immune factors, are produced and act on the reproductive system. However, TNFα is also an important physiological player in the ovulatory process in mammals. more...
Organism:
Oncorhynchus mykiss
Type:
Expression profiling by array
Platform:
GPL10092
1 Sample
Download data: TXT
Series
Accession:
GSE20296
ID:
200020296

Supplemental Content

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