GEO DataSets

(Submitter supplied) Is there a correlation between miRNA diversity and levels of organismic complexity? Exhibiting extraordinary levels of morphological and developmental complexity, insects are the most diverse animal class on earth. Their evolutionary success was in particular shaped by the innovation of holometabolan metamorphosis in endopterygotes. Previously, miRNA evolution had been linked to morphological complexity, but astonishing variation in the currently available miRNA complements of insects made this link unclear. more...

Organism:

Blattella germanica

Type:

Non-coding RNA profiling by high throughput sequencing

Platform:

GPL22010

4 Samples

Download data: CSV

(Submitter supplied) Do miRNAs contribute to specify the germ-band type and the body structure in the insect embryo? Our goal was to address that issue by studying the changes in miRNA expression along the ontogeny of the German cockroach Blattella germanica, which is a short germ-band and hemimetabolan species. We sequenced small RNA libraries representing 11 developmental stages of B. germanica ontogeny (with especial emphasis on embryogenesis) and the changes in miRNA expression were examined. more...

Organism:

Blattella germanica

Type:

Non-coding RNA profiling by high throughput sequencing

Platform:

GPL22038

22 Samples

Download data: CSV

(Submitter supplied) microRNAs (miRNAs) have been reported as key regulators in the post-transcriptional process in eukaryotic cells. In insects most of the studies have been reported in holometabolans while only recently two hemimetabolans  (Locusta migratoria and Acyrthosiphonpisum) have had their miRNAs identified. Therefore, the study on miRNAs of the evolutionarily basal hemimetabolan  Blattella germanica, may provide valuable insights on the structural and functional evolution of miRNAs. more...

Organism:

Blattella germanica

Type:

Non-coding RNA profiling by high throughput sequencing

Platform:

GPL10675

2 Samples

Download data: TXT

(Submitter supplied) Characterization of miRNAs in red flour beetle Tribolium castaneum by deep sequencing of two different RNA libraries.

Organism:

Tribolium castaneum

Type:

Non-coding RNA profiling by high throughput sequencing

Platform:

GPL11311

2 Samples

Download data

(Submitter supplied) MicroRNAs (miRNAs) are endogenous RNA molecules that contribute to the regulation of gene expression post-transcriptionally. Recently, patterns of sequence evolution and evolutionary emergence of miRNAs have been analyzed in detail. However, the extent to which miRNA expression levels vary within and between species, the role of stabilizing selection versus other evolutionary mechanisms in shaping the temporal dynamics of these changes, and how this variation might unveil the interplay between miRNAs and mRNAs remain poorly understood. more...

Organism:

Drosophila melanogaster; Drosophila simulans; Drosophila yakuba

Type:

Non-coding RNA profiling by high throughput sequencing

Platforms:

GPL9394 GPL11000 GPL9058

12 Samples

Download data: TXT, XLS

(Submitter supplied) We found two lines of evidence suggesting that miRNA abundance has been shaped by different evolutionary regimes at the two developmental stages. Attributed to functional constraints, which points to mechanisms more subtle and diverse than previously thought.

Organism:

Drosophila simulans; Drosophila yakuba; Drosophila melanogaster

Type:

Non-coding RNA profiling by array

Platform:

GPL18365

72 Samples

Download data: TXT

(Submitter supplied) We found two lines of evidence suggesting that miRNA abundance has been shaped by different evolutionary regimes at the two developmental stages attributed to functional constraints, which points to mechanisms more subtle and diverse than previously thought.

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL14007

24 Samples

Download data: PAIR