GEO DataSets

(Submitter supplied) Iron is the fourth most abundant element in the Earth’s crust. However, the poor solubility of iron due to oxidation of ferrous iron to the almost insoluble ferric iron under aerobic conditions constitutes a considerable challenge for living organisms to obtain sufficient amounts of the iron available. In the present study, we set out to characterize the global gene expression of C. glutamicum under iron limitation in comparison to iron-replete conditions.

Organism:

Pseudomonas putida; Gluconobacter oxydans; Escherichia coli; Corynebacterium glutamicum; Corynebacterium glutamicum ATCC 13032; Bacillus subtilis subsp. subtilis str. 168

Type:

Expression profiling by array

Platform:

GPL22794

3 Samples

Download data: GPR

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Gluconobacter oxydans; Corynebacterium glutamicum ATCC 13032; Escherichia coli; Corynebacterium glutamicum; Pseudomonas putida; Bacillus subtilis subsp. subtilis str. 168

Type:

Expression profiling by array

Platforms:

GPL22794 GPL22792

6 Samples

Download data: GPR

(Submitter supplied) Iron is the fourth most abundant element in the Earth’s crust. However, the poor solubility of iron due to oxidation of ferrous iron to the almost insoluble ferric iron under aerobic conditions constitutes a considerable challenge for living organisms to obtain sufficient amounts of the iron available. In the present study, we set out to characterize the global gene expression of C. glutamicum under iron limitation in comparison to iron-replete conditions.

Organism:

Escherichia coli; Corynebacterium glutamicum; Corynebacterium glutamicum ATCC 13032; Gluconobacter oxydans; Bacillus subtilis subsp. subtilis str. 168

Type:

Expression profiling by array

Platform:

GPL22792

3 Samples

Download data: GPR

(Submitter supplied) The pyruvate dehydrogenase complex (PDHC) catalyzes the oxidative decarboxylation of pyruvate yielding acetyl-CoA and CO2. The PDHC-deficient Corynebacterium glutamicum strain ΔaceE is therefore lacking an important decarboxylation step in central metabolism. Additional inactivation of pyc, encoding pyruvate carboxylase, resulted in a >15 hour lag phase in the presence of glucose, while no growth defect was observed on gluconeogenetic substrates like acetate. more...

Organism:

Gluconobacter oxydans; Bacillus subtilis subsp. subtilis str. 168; Pseudomonas putida KT2440; Escherichia coli; Corynebacterium glutamicum; Corynebacterium glutamicum ATCC 13032

Type:

Expression profiling by array

Platform:

GPL26911

3 Samples

Download data: GPR

(Submitter supplied) The response regulator HrrA belonging to the HrrSA two-component system (previously named CgtSR11) is known to be repressed by the global iron-dependent regulator DtxR in Corynebacterium glutamicum. Sequence analysis indicated an involvement of the HrrSA system in heme-dependent gene expression. Growth experiments revealed that the non-pathogenic soil bacterium C. glutamicum is able to use hemin or hemoglobin as sole iron source. more...

Organism:

Corynebacterium glutamicum ATCC 13032

Type:

Expression profiling by array

Platform:

GPL9860

9 Samples

Download data: GPR

(Submitter supplied) Comparative transcriptome analyses revealed 69 genes exhibiting ≥2-fold mRNA level changes in C. glutamicum DfkpA.Overall, 34 genes exhibited ≥2-fold increased and 35 genes at least 0.5-fold decreased mRNA levels in JVO1 DfkpA. About half of these genes (32) encode for hypothetical/putative proteins. LdhA encoding L-lactate dehydrogenase exhibited by far the strongest increased mRNA level (8.5-fold) in the absence of FkpA. more...

Organism:

Corynebacterium glutamicum; Corynebacterium glutamicum ATCC 13032

Type:

Expression profiling by array

Platform:

GPL15451

2 Samples

Download data: GPR

(Submitter supplied) Corynebacterium glutamicum, a gram-positive soil bacterium used for the industrial production of amino acids such as L-glutamate and L-lysine, is able to use a number of different nitrogen sources, such as ammonium, urea, or creatinine. In this communication, we show that L-glutamine serves as an excellent nitrogen source for C. glutamicum and allows similar growth rates in glucose minimal medium as ammonium. more...

Organism:

Corynebacterium glutamicum ATCC 13032

Type:

Expression profiling by array

Platform:

GPL9860

3 Samples

Download data: GPR

(Submitter supplied) RNA-seq differential gene expression profiling of Corynebacterium pseudotuberculosis under iron limitation. We use two C. pseudotuberculosis strains, a ciuA Cp13 mutant and its parental wild type T1 strain to quantify the relative gene expression of these strains in cultures with low iron availability. The ciuA Cp13 mutant is deficient for an operon which encodes a iron siderophore uptake system. The Cp13 mutant also showed reduced virulence in CLA infection models. more...

Organism:

Corynebacterium pseudotuberculosis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL24971

14 Samples

Download data: TXT

(Submitter supplied) We investigated the gene expression responses of Candidatus Pelagibacter ubique cultures to iron limitation. Differential expression was observed for genes in iron acquisition and incorporation operons. SfuC in particular was 16 times higher in iron-limited cultures and encodes a periplasmic iron-binding protein.

Organism:

Candidatus Pelagibacter ubique HTCC1002; Candidatus Pelagibacter ubique HTCC1062; Candidatus Pelagibacter sp. HTCC7211

Type:

Expression profiling by array

Platform:

GPL7330

18 Samples

Download data: CEL

(Submitter supplied) Differential gene expression analysis of C. glutamicum C1 in presence of 3 mM indole-alanine dipeptide compared to control conditions without indole-alanine dipeptide. C. glutamicum C1 cells were cultivated in CGXII minimal medium with 40 g per litre glucose in presence or absence of 3 mM indole-alanine dipeptide and harvested during exponential phase (o.d.600 6).

Organism:

Corynebacterium glutamicum

Type:

Expression profiling by high throughput sequencing

Platform:

GPL29269

6 Samples

Download data: TXT

(Submitter supplied) Differential gene expression analysis of C. glutamicum ATCC 13032 in presence of 2.5 mM indole compared to control conditions without indole. C. glutamicum ATCC 13032 cells were cultivated in CGXII minimal medium with 40 g per litre glucose in presence of 2.5 mM indole and harvested during exponential phase (o.d.600 4).

Organism:

Corynebacterium glutamicum

Type:

Expression profiling by high throughput sequencing

Platform:

GPL29269

2 Samples

Download data: TXT

(Submitter supplied) In an evolutionary experiment on high hemin concentrations, a frameshift mutation in the ChrS gene was figured out to be striking in survival at high hemin concentrations (Ala245fs). Apart from high upregulation of heme exporter hrtB, microarrays should reveal further different controlled genes compared to the WT.

Organism:

Corynebacterium glutamicum; Bacillus subtilis subsp. subtilis str. 168; Gluconobacter oxydans 621H; Escherichia coli str. K-12 substr. MG1655; Pseudomonas putida KT2440

Type:

Expression profiling by array

Platform:

GPL32387

3 Samples

Download data: GPR