GEO DataSets

(Submitter supplied) Background: The uncontrolled and widespread use of (nano)silver compounds has led to the increased release of these compounds into the environment, raising concerns about their negative impact on ecosystems. Concomitantly, silver resistance determinants are widely spread among environmental and clinically relevant bacteria although the underlying mechanisms are not yet fully understood. Results: In this study, we show that Cupriavidus metallidurans is able to adapt to toxic silver concentrations and explicate the genetic circuit responsible for this adaptation. more...

Organism:

Cupriavidus metallidurans; Cupriavidus metallidurans CH34

Type:

Expression profiling by array

Platform:

GPL4980

18 Samples

Download data: GPR

(Submitter supplied) Response of Cupriavidus metallidurans AE104 and 2 deletion mutants to Zn and EDTA

Organism:

Cupriavidus metallidurans; Cupriavidus metallidurans CH34

Type:

Expression profiling by array

Platform:

GPL16115

27 Samples

Download data: TXT

(Submitter supplied) Response of Cupriavidus metallidurans CH34 to NaAuCl4, Au(I)-thiomalate, Au(I)-thiosulfate, KAuCN, (KCN as control)

Organism:

Cupriavidus metallidurans CH34

Type:

Expression profiling by array

Platform:

GPL16115

24 Samples

Download data: TXT

(Submitter supplied) Different Cupriavidus metallidurans strains isolated from metal-contaminated and other anthropogenic environments were genotypically and phenotypically compared with C. metallidurans type strain CH34. The latter is well-studied for its resistance to a wide range of metals, which is carried for a substantial part by its two megaplasmids pMOL28 and pMOL30. Comparative genomic hybridization (CGH) indicated that the extensive arsenal of determinants involved in metal resistance was well conserved among the different C. more...

Organism:

Cupriavidus metallidurans; Cupriavidus metallidurans CH34

Type:

Genome variation profiling by genome tiling array

Platform:

GPL4980

15 Samples

Download data: GPR

(Submitter supplied) Whole-genome expression microarray experiments were conducted to assess the response of C. metallidurans CH34 to aqueous Au(III)-chloride and identify possible biochemical pathways for Au detoxification. Four microarray experiments were conducted to assess gold response at low, medium and high Au(III)-chloride concentrations (i.e., 10, 50 and 100 µM Au(III)-chloride) and different induction times (10 and 30 minutes with 50 µM Au(III)-chloride). more...

Organism:

Cupriavidus metallidurans CH34

Type:

Expression profiling by array

Platform:

GPL4980

4 Samples

Download data: GPR

(Submitter supplied) Cupriavidus metallidurans CH34 is a metal resistant beta-proteobacterium. The genome of this bacterium contain many genes involved in heavy metal resistance. Gene expression of C. metallidurans was studied after the addition of of Zn(II), Cd(II), Cu(II), Ni(II), Pb(II), Hg(II) or Co(II). Keywords: Heavy metal stress response

Organism:

Cupriavidus metallidurans CH34

Type:

Expression profiling by array

Platform:

GPL4980

7 Samples

Download data: GPR

(Submitter supplied) Background: The high number of heavy metal resistance genes in the soil bacterium Cupriavidus metallidurans CH34 makes it an interesting model organism to study microbial responses to heavy metals. Results: In this study the transcriptional response of this bacterium was measured after challenging it to a wide range of sub-lethal concentrations of various essential or toxic metals. Considering the global transcriptional responses for each challenge as well as by identifying the overlap in upregulated genes between different metal responses, the sixteen metals could be clustered in three different groups. more...

Organism:

Cupriavidus metallidurans CH34

Type:

Expression profiling by array

Platform:

GPL4980

42 Samples

Download data: GPR

(Submitter supplied) The weathering of volcanic minerals makes a significant contribution to the global silicate weathering budget, influencing carbon dioxide drawdown and climate control. Basalt rocks may account for over 30% of the global carbon dioxide drawdown in silicate weathering. Yet the genetics of biological rock weathering are unknown. For the first time, we apply a DNA microarray to investigate the genes involved in weathering by the heavy metal resistant organism, Cupriavidus metallidurans CH34; in particular we investigate the sequestering of iron. more...

Organism:

Cupriavidus metallidurans CH34

Type:

Expression profiling by array

Platform:

GPL4980

3 Samples

Download data: GPR

(Submitter supplied) Response of Cupriavidus metallidurans CH34, AE104 and delta zupT mutant to Zn/EDTA stress

Organism:

Cupriavidus metallidurans CH34

Type:

Expression profiling by array

Platform:

GPL16115

16 Samples

Download data: TXT

(Submitter supplied) Response of Cupriavidus metallidurans CH34 and ECF deletion mutants to mixed metals

Organism:

Cupriavidus metallidurans CH34; Cupriavidus metallidurans

Type:

Expression profiling by array

Platform:

GPL16115

16 Samples

Download data: TXT

(Submitter supplied) Response of Cupriavidus metallidurans AE104 and delta zur mutant to Zn stress

Organism:

Cupriavidus metallidurans CH34

Type:

Expression profiling by array

Platform:

GPL16115

9 Samples

Download data: TXT

(Submitter supplied) Response of Cupriavidus metallidurans AE104(delta zupT) mutant to Zn/EDTA stress

Organism:

Cupriavidus metallidurans CH34

Type:

Expression profiling by array

Platform:

GPL16115

6 Samples

Download data: TXT

(Submitter supplied) Bacteria can respond to adverse environments by increasing their genomic variability and subsequently facilitating adaptive evolution. To demonstrate this, the contribution of Insertion Sequence (IS) elements to the genetic adaptation of Cupriavidus metallidurans AE126 to toxic zinc concentrations was determined. This derivative of type strain CH34, devoid of its main zinc resistance determinant, is still able to increase its zinc resistance level. more...

Organism:

Cupriavidus metallidurans CH34; Cupriavidus metallidurans

Type:

Expression profiling by genome tiling array

Platform:

GPL4980

9 Samples

Download data: GPR