Similar studies for GEO DataSets (Select 200113897) - GEO DataSets

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Items: 20

Select item 2001138971.

Application of Next Generation Sequencing (RNA-seq and miRNA-seq) to study the molecular signature of Aluminium hydroxide adjuvant in ovine peripheral blood mononuclear cells (PBMCs) [miRNA-Seq]

(Submitter supplied) We report the application of miRNA sequencing technology for high-throughput profiling of the aluminium hydroxide adjuvant mechanism of action in an in vivo experiment on sheep. We mapped about 13 million sequence reads per sample to the sheep genome (build Oar3.1) and identified 95 miRNAs in the PBMCs of sheep treated with commercial vaccines or with the adjuvant alone. A total of 3, 6 and 1 differentialy expressed miRNAs were identified in the vaccine tf VS vaccine t0, adjuvant tf VS adjuvant t0 and adjuvant tf VS vaccine tf comparisons, respectively. more...

Organism:: Ovis aries

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL19778
12 Samples

Download data: TXT

Series

Accession:: GSE113897

ID:: 200113897

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001285972.

Application of Next Generation Sequencing (RNA-seq and miRNA-seq) to study the molecular signature of Aluminium hydroxide adjuvant in ovine encephalon.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Ovis aries

Type:: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing

Platforms:: GPL15670 GPL19778
25 Samples

Download data

Series

Accession:: GSE128597

ID:: 200128597

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Select item 2001285963.

Application of Next Generation Sequencing (RNA-seq and miRNA-seq) to study the molecular signature of Aluminium hydroxide adjuvant in ovine encephalon. [miRNA-Seq]

(Submitter supplied) We report the application of miRNA sequencing technology for high-throughput profiling of the aluminium hydroxide adjuvant mechanism of action in an in vivo experiment on sheep. We mapped about 13.1 million sequence reads per sample to the sheep genome (build Oar3.1) and identified 299 miRNAs in the encephalon of sheep treated with commercial vaccines, with the adjuvant alone or with PBS (control group). more...

Organism:: Ovis aries

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL19778
13 Samples

Download data: TXT

Series

Accession:: GSE128596

ID:: 200128596

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Select item 2001285954.

Application of Next Generation Sequencing (RNA-seq and miRNA-seq) to study the molecular signature of Aluminium hydroxide adjuvant in ovine encephalon. [RNA-Seq]

(Submitter supplied) We report the application of RNA sequencing technology for high-throughput profiling of the aluminium hydroxide adjuvant mechanism of action in an in vivo experiment on sheep treated with commercial vaccines, with the adjuvant alone or with PBS (control group). We mapped about 74.1 million sequence reads per sample to the sheep genome (build Oar3.1) and after filtering 16,369 genes were expressed, of which 14,387 were annotated genes in Ensembl and 1,982 were candidate lncRNAs. more...

Organism:: Ovis aries

Type:: Expression profiling by high throughput sequencing

Platform:: GPL15670
12 Samples

Download data: GTF, TXT

Series

Accession:: GSE128595

ID:: 200128595

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Select item 2001138995.

Molecular signature of Aluminum hydroxide adjuvant in ovine PBMCs by integrated mRNA and microRNA transcriptome sequencing

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Ovis aries

Type:: Non-coding RNA profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platforms:: GPL15670 GPL19778
25 Samples

Download data

Series

Accession:: GSE113899

ID:: 200113899

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Select item 2001138986.

Application of Next Generation Sequencing (RNA-seq and miRNA-seq) to study the molecular signature of Aluminium hydroxide adjuvant in ovine peripheral blood mononuclear cells (PBMCs) [RNA-Seq]

(Submitter supplied) We report the application of RNA sequencing technology for high-throughput profiling of the aluminium hydroxide adjuvant mechanism of action in an in vivo experiment on sheep. We mapped about 52 million sequence reads per sample to the sheep genome (build Oar3.1) and identified 21,274 genes in the PBMCs of sheep treated with commercial vaccines or with the adjuvant alone. A total of 2473, 2980 and 429 differentialy expressed genes were identified in the vaccine tf VS vaccine t0, adjuvant tf VS adjuvant t0 and adjuvant tf VS vaccine tf comparisons, respectively. more...

Organism:: Ovis aries

Type:: Expression profiling by high throughput sequencing

Platform:: GPL15670
13 Samples

Download data: TXT

Series

Accession:: GSE113898

ID:: 200113898

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Select item 2001187507.

Profiling and bioinformatics analyses reveal differential expression of circular RNA in tongue cancer revealed by high-throughput sequencing

(Submitter supplied) Circular RNAs (circRNA) are special non-coding RNAs. They are widely present, but with unknown functions. Recent studies have shown that many endogenous circRNAs have sponge function to absorb microRNAs. They can regulate target gene mRNA expression and play important roles in many biological processes. However, expression profile and function of circRNAs in human TSCC haven’t been reported. High-throughput sequencing was performed to identify and annotate from three TSCC tissues and adjacent tissues. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL20301
6 Samples

Download data: XLS

Series

Accession:: GSE118750

ID:: 200118750

Select item 2001206638.

Transcriptome Analysis of PBMCs in peripheral blood of patients with hepatocellular carcinoma

(Submitter supplied) The aim of this study was to analyze the expression profile of circRNAs in PBMCs in peripheral blood of patients with hepatocellular carcinoma (HCC) by next-generation sequencing, and to identify potential markers for early diagnosis and prognosis of HCC, and to lay a foundation for further study on the mechanism of this molecule in PBMCs.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL20795
7 Samples

Download data: TXT

Series

Accession:: GSE120663

ID:: 200120663

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Select item 2001805969.

Identification and characterization of miRNAs in spleens of sheep subjected to repetitive vaccination

(Submitter supplied) Spleen miRNA profiles of twelve age-matched Rasa sheep after inoculation of nine different commercial vaccines based of aluminium hydroxide (the vaccine group composed of 4 animals), with the aluminium adjuvant alone in an equivalent dose (the adjuvant group composed of 4 animals) or PBS (the control group composed of 5 animals) were generated by deep sequencing on an Illumina HiSeq2500 sequencer.

Organism:: Ovis aries

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL19778
12 Samples

Download data: TXT, XLSX

Series

Accession:: GSE180596

ID:: 200180596

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Select item 20011661710.

Expression data of circRNA from new diagnostic AML patients (with or without EMI) and healthy volunteers

(Submitter supplied) CircRNA microarray was conducted to further explore the underlying circRNA expression alterations in extramedullary infiltration (EMI) of AML. 4 matched samples from EMI, non-EMI AML patients and healthy volunteers were selected. Mononuclear cells from 12 bone marrow samples were separated according to protocols. RNA was then extracted and hybridization for further microarray analysis.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL21825
12 Samples

Download data: TXT

Series

Accession:: GSE116617

ID:: 200116617

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Select item 20011661611.

Expression data of whole genome from new diagnostic AML patients (with or without EMI) and healthy volunteers

(Submitter supplied) Whole Genome microarray was conducted to further explore the underlying gene expression alterations in extramedullary infiltration (EMI) of AML. 4 matched samples from EMI, non-EMI AML patients and healthy volunteers were selected. Mononuclear cells from 12 bone marrow samples were separated according to protocols. RNA was then extracted and hybridization for further microarray analysis.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL13497
12 Samples

Download data: TXT

Series

Accession:: GSE116616

ID:: 200116616

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Select item 20015189412.

Transcriptome analysis induced by CTN, CV-A16, CVS and EV-A71 infection

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL20795
12 Samples

Download data

Series

Accession:: GSE151894

ID:: 200151894

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Select item 20015189313.

Transcriptome analysis induced by EV-A71 infection

(Submitter supplied) In this study, we aimed to adopt the transcriptome sequencing technology to obtain the different changes of transcriptome profiles after infecting with EV-A71 in human neuroblastoma cell line SH-SY5Y. And then, through systematic bioinformatics analysis, we hope to find useful clues for the pathogenesis of HFMD.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL20795
3 Samples

Download data: TXT

Series

Accession:: GSE151893

ID:: 200151893

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Select item 20015189214.

Transcriptome analysis induced by CVS infection

(Submitter supplied) In this study, we aimed to adopt the transcriptome sequencing technology to obtain the different changes of transcriptome profiles after infecting with CVS in human neuroblastoma cell line SH-SY5Y. And then, through systematic bioinformatics analysis, we hope to find useful clues for the pathogenesis of Rabies.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL20795
3 Samples

Download data: TXT

Series

Accession:: GSE151892

ID:: 200151892

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Select item 20015189115.

Transcriptome analysis induced by CV-A16 infection

(Submitter supplied) In this study, we aimed to adopt the transcriptome sequencing technology to obtain the different changes of transcriptome profiles after infecting with CV-A16 in human neuroblastoma cell line SH-SY5Y. And then, through systematic bioinformatics analysis, we hope to find useful clues for the pathogenesis of HFMD.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL20795
3 Samples

Download data: TXT

Series

Accession:: GSE151891

ID:: 200151891

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 20015189016.

Transcriptome analysis induced by CTN infection

(Submitter supplied) In this study, we aimed to adopt the transcriptome sequencing technology to obtain the different changes of transcriptome profiles after infecting with CTN in human neuroblastoma cell line SH-SY5Y. And then, through systematic bioinformatics analysis, we hope to find useful clues for the pathogenesis of Rabies.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL20795
3 Samples

Download data: TXT

Series

Accession:: GSE151890

ID:: 200151890

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Select item 20014931517.

circRNA expression pattern in the pathogenesis of aseptic lossening

(Submitter supplied) Increasing evidence has demonstrated that circular RNA exerts important function in the pathogenesis of some diseases. While, the contributions of circRNAs to aseptic lossening after total hip arthroplasty remain largely unknown. Our research is to explore the differently expressed circRNAs and elucidate complex regulated mechanism of circRNAs in aseptic lossening. The differently expressed circRNAs were identified by RNA sequencing analysis. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by high throughput sequencing

Platform:: GPL20301
6 Samples

Download data: XLSX

Series

Accession:: GSE149315

ID:: 200149315

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Select item 20020478018.

Circular RNA Profiling in Peripheral Blood Mononuclear Cells from Retinopathy of Prematurity

(Submitter supplied) To reveal the altered expression profiles of circular RNAs (circRNAs) in the peripheral blood mononuclear cells (PBMCs) of patients with retinopathy of prematurity (ROP), microarray analysis was conducted in the samples from ROP patients and controls.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL21825
10 Samples

Download data: TXT

Series

Accession:: GSE204780

ID:: 200204780

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Select item 20016262719.

Merkel Cell Polyomavirus Encodes Circular RNAs (circRNAs) Enabling a Dynamic circRNA/microRNA/mRNA Regulatory Network

(Submitter supplied) Viral noncoding RNAs have acquired increasing prominence as important regulators of infection and mediators of pathogenesis. Circular RNAs (circRNAs) generated by backsplicing events have been identified in several oncogenic human DNA viruses. Here, we show that Merkel cell polyomavirus (MCV), the etiologic cause of ~80% of Merkel cell carcinomas (MCCs), also expresses circular RNAs. By RNase R-resistant RNA sequencing, four putative circRNA backsplice junctions (BSJs) were identified from the MCV early region (ER). more...