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Links from GEO DataSets

Items: 5

1.

The evolution, evolvability, and engineering of gene regulatory DNA [RNA-seq]

(Submitter supplied) Here, we used RNA-seq to quantify expression conservation across many Ascomycete yeasts.
Organism:
Lachancea waltii; Saccharomyces cerevisiae; Candida albicans; Schizosaccharomyces japonicus; Schizosaccharomyces octosporus; Saccharomyces bayanus; Yarrowia lipolytica; Naumovozyma castellii; Schizosaccharomyces pombe; Nakaseomyces glabratus; Kluyveromyces lactis
Type:
Expression profiling by high throughput sequencing
11 related Platforms
11 Samples
Download data: TXT
Series
Accession:
GSE163866
ID:
200163866
2.

The evolution, evolvability, and engineering of gene regulatory DNA [GPRA]

(Submitter supplied) In order to generate data produce a generalizable sequence-to-expression model, we randomly sampled ~21 million 80 bp sequences and tested their activity as promoters (in yeast) by measuring expression level by FACS (sorting into 18 bins).
Organism:
Saccharomyces cerevisiae
Type:
Other
Platform:
GPL19756
36 Samples
Download data: TXT
Series
Accession:
GSE163045
ID:
200163045
3.

Mutation accumulation and the yeast transcriptome

(Submitter supplied) Spontaneous mutations were accumulated in haploid strains of yeast. Expression profiling was performed on four MA lines and the ancestor in a complete loop design. Keywords: Gene expression profiling
Organism:
Saccharomyces cerevisiae
Type:
Expression profiling by array
Platform:
GPL5092
10 Samples
Download data
Series
Accession:
GSE7537
ID:
200007537
4.

BP001-002: The genomic landscape of compensatory evolution

(Submitter supplied) Adaptive evolution is generally assumed to progress through the accumulation of beneficial mutations. However, deleterious mutations may also have an important role by promoting adaptive genetic changes that are otherwise inaccessible. Here we study the capacity of the baker’s yeast genome to compensate the complete loss of genes during evolution, and explore the long-term consequences of this process. more...
Organism:
Saccharomyces cerevisiae BY4741; Saccharomyces cerevisiae
Type:
Expression profiling by array
Platform:
GPL11232
34 Samples
Download data: TXT
Series
Accession:
GSE55373
ID:
200055373
5.

Mechanisms of Adaptive Evolution of Aneuploid Cells

(Submitter supplied) Alteration of normal ploidy (aneuploidy) is an important mechanism of evolution of species. It has been linked to a rapid response to stress and is regarded as a hallmark of cancer. While increased genomic instability of aneuploid cells can accelerate genetic diversification and facilitate adaptation, these cells also face the adverse effects of gene imbalance, resulting in fitness cost. Here, to understand the mechanisms through which cells respond to aneuploidy and develop tolerance leading to fitness restoration, we subjected disomic (i.e. more...
Organism:
Saccharomyces cerevisiae W303
Type:
Expression profiling by high throughput sequencing
Platform:
GPL25517
45 Samples
Download data: TSV
Series
Accession:
GSE119272
ID:
200119272
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Supplemental Content

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