Similar studies for GEO DataSets (Select 200184232) - GEO DataSets

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Items: 20

Select item 2001842321.

Investigate the effect of gain of HAND2 on chromatin accessibility.

(Submitter supplied) The overexpression of HAND2 in IMR32 cells results in a increase of chromation accessibility at the HAND2 and MYCN common binding sites.

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL18573
4 Samples

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Series

Accession:: GSE184232

ID:: 200184232

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Select item 2002084242.

The cooperation between MYCN and its cofactors WDR5 and G9a

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL20301 GPL18573 GPL24676
56 Samples

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Series

Accession:: GSE208424

ID:: 200208424

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Select item 2002084233.

RNA-sequencing analysis to identify genes regulated by MYCN in rhabdomyosarcoma cell line RH4

(Submitter supplied) In this study we identified genes regulated by MYCN in RH4 cells

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24676
6 Samples

Download data: TXT

Series

Accession:: GSE208423

ID:: 200208423

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Select item 2002084224.

RNA-sequencing analysis to identify genes regulated by MYCN in neuroblastoma cell line SHEP by MYCN overexpression

(Submitter supplied) In this study we identified genes regulated by MYCN in SHEP cells

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL20301
6 Samples

Download data: TXT

Series

Accession:: GSE208422

ID:: 200208422

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Select item 2002084215.

RNA-sequencing analysis to identify genes regulated by MYCN in neuroblastoma cell line KCNR.

(Submitter supplied) In this study we identified genes regulated by MYCN in KCNR cells

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24676
6 Samples

Download data: TXT

Series

Accession:: GSE208421

ID:: 200208421

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Select item 2002084206.

RNA-sequencing analysis to identify genes regulated by MYCN, WDR5 and G9a in neuroblastoma cell line IMR32

(Submitter supplied) In this study we identified genes regulated by MYCN, WDR5 and G9a in IMR32 cells

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24676
12 Samples

Download data: TXT

Series

Accession:: GSE208420

ID:: 200208420

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Select item 2002084197.

The cooperation between MYCN and its cofactors WDR5 and G9a on gene transcription regulation [siWDR5]

(Submitter supplied) MYCN cooperates with WDR5 to activate canonical MYC targets and cooperates with G9a to repress neuronal differentiation genes.

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL18573
6 Samples

Download data: BW

Series

Accession:: GSE208419

ID:: 200208419

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Select item 2002084178.

The cooperation between MYCN and its cofactors WDR5 and G9a on gene transcription regulation [siG9a]

(Submitter supplied) MYCN cooperates with WDR5 to activate canonical MYC targets and cooperates with G9a to repress neuronal differentiation genes.

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL18573
4 Samples

Download data: BW

Series

Accession:: GSE208417

ID:: 200208417

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Select item 2002084149.

The cooperation between MYCN and its cofactors WDR5 and G9a on gene transcription regulation [siMYCN]

(Submitter supplied) MYCN cooperates with WDR5 to activate canonical MYC targets and cooperates with G9a to repress neuronal differentiation genes.

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL18573
16 Samples

Download data: BW

Series

Accession:: GSE208414

ID:: 200208414

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Select item 20018422910.

Investigate the effect of loss of HAND2, MYCN, PHOX2B and GATA3 on chromatin accessibility.

(Submitter supplied) The knockdown of HAND2 in IMR32 cells results in a decrease of chromation accessibility at the HAND2 and MYCN common binding sites.

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL18573
14 Samples

Download data: BW

Series

Accession:: GSE184229

ID:: 200184229

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Select item 20018405911.

The cooperation between HAND2 and MYCN on DNA binding [HAND2-overexpression_ChIPseq]

(Submitter supplied) HAND2 assists MYCN bind to DNA.

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL18573
12 Samples

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Series

Accession:: GSE184059

ID:: 200184059

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Select item 20018405812.

HAND2 regulates regional chromation modification [HAND2-knockdown_histone_ChIPseq]

(Submitter supplied) The knockdown of HAND2 affects the regional chromation modification.

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL18573
14 Samples

Download data: BW

Series

Accession:: GSE184058

ID:: 200184058

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Select item 20018405713.

The cooperation among the core regulatory circuitry transcription factors and MYCN on DNA binding [HAND2-MYCN-CRC-knockdown_ChIPseq]

(Submitter supplied) MYCN and the core regulatory circuitry transcription factors HAND2, PHOX2B and GATA3 cooperate to bind to DNA.

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL18573
36 Samples

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Series

Accession:: GSE184057

ID:: 200184057

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20018364114.

Analysis of HAND2 and MYCN

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL20301 GPL18573
101 Samples

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Series

Accession:: GSE183641

ID:: 200183641

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Select item 20018363615.

RNA-sequencing analysis to investigate genes regulated by HAND2 and MYCN in LAN5 cells

(Submitter supplied) In this study we identified genes regulated by HAND2 or MYCN or both MYCN and HAND2 in LAN5 cells.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL20301
9 Samples

Download data: TXT

Series

Accession:: GSE183636

ID:: 200183636

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Select item 20018360916.

RNA-sequencing analysis to investigate genes regulated by HAND2 and MYCN in IMR32 cells

(Submitter supplied) In this study we identified genes regulated by HAND2 or MYCN or both MYCN and HAND2 in IMR32 cells.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL20301
12 Samples

Download data: TXT

Series

Accession:: GSE183609

ID:: 200183609

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Select item 20010891417.

Super-enhancer Driven Core Regulatory Circuitry in MYCN-amplified Neuroblastoma [array]

(Submitter supplied) Transcriptional dysregulation plays a major role in the development and progression of human tumors such as pediatric neuroblastoma. Therefore, we sought to elucidate the relationship between genes required for neuroblastoma cell growth and survival and the transcriptional core regulatory circuitry (CRC) that controls the gene expression program. A genome-scale CRISPR-Cas9 screen for oncogenic dependencies revealed that 143 genes are essential for cell survival and growth in neuroblastoma relative to other cancers, including many super-enhancer (SE) regulated transcription factors. more...